Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Christopher P. Selby"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Plants use nucleotide excision repair to maintain genome integrity in response to damage caused by stresses such as UV radiation. Here Oztas et al. use genome-wide profiling to show that excision repair in Arabidopsis is strongly coupled to transcrip
Externí odkaz:
https://doaj.org/article/20ce9808d2ae4e69b9bccd3722398343
Autor:
Hagoon Jang, Gha Young Lee, Christopher P. Selby, Gung Lee, Yong Geun Jeon, Jae Ho Lee, Kenneth King Yip Cheng, Paul Titchenell, Morris J. Birnbaum, Aimin Xu, Aziz Sancar, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic gluc
Externí odkaz:
https://doaj.org/article/8d7c5bde883440f7b735e96aacbc548c
Publikováno v:
Annual Review of Biochemistry. 92
Transcription-coupled repair (TCR), discovered as the preferential nucleotide excision repair of UV-induced cyclobutane pyrimidine dimers located in transcribed mammalian genes compared to those in nontranscribed regions of the genome, is defined as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4cd64031fafbdf079b74588ea09e8a
https://doi.org/10.1146/annurev-biochem-041522-034232
https://doi.org/10.1146/annurev-biochem-041522-034232
Autor:
Ogun Adebali, Yanyan Yang, Pradeep Neupane, Nneka I. Dike, Julia L. Boltz, Cansu Kose, Miriam Braunstein, Christopher P. Selby, Aziz Sancar, Laura A. Lindsey-Boltz
Publikováno v:
Journal of Biological Chemistry. 299:103009
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3707fcb4c256b64eaa5f1d27f34d6e
https://doi.org/10.1016/j.jbc.2023.103009
https://doi.org/10.1016/j.jbc.2023.103009
Publikováno v:
Journal of Biological Chemistry. 299:102929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c742a92dbc462a60e5c03f986b821e5
https://doi.org/10.1016/j.jbc.2023.102929
https://doi.org/10.1016/j.jbc.2023.102929
Publikováno v:
J Biol Chem
Platinum-based chemotherapies, including oxaliplatin, are a mainstay in the management of solid tumors and induce cell death by forming intrastrand dinucleotide DNA adducts. Despite their common use, they are highly toxic, and approximately half of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fcf06343139bfe0e136a16ad527e7a
https://doi.org/10.1074/jbc.ra120.013347
https://doi.org/10.1074/jbc.ra120.013347
Autor:
Nazli Deger, Xuemei Cao, Christopher P. Selby, Saygin Gulec, Hiroaki Kawara, Evan B. Dewey, Li Wang, Yanyan Yang, Sierra Archibald, Berkay Selcuk, Ogun Adebali, Jeff Sekelsky, Aziz Sancar, Zhenxing Liu
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance We have discovered that Drosophila , which does not have the canonical TCR homologs, does nevertheless carry out TCR as efficiently as organisms that do. Furthermore, using the XR-seq and in vivo excision assay we have also shown that bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138fb15e44c784b99c9b4d7b953c71cf
https://doi.org/10.1073/pnas.2123163119
https://doi.org/10.1073/pnas.2123163119
Publikováno v:
The Journal of biological chemistry. 298(5)
Nucleotide excision repair functions to protect genome integrity, and ongoing studies using excision repair sequencing (XR-seq) have contributed to our understanding of how cells prioritize repair across the genome. In this method, the products of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23411a06187d0f40c1891f74c8f0fa01
https://pubmed.ncbi.nlm.nih.gov/35339490
https://pubmed.ncbi.nlm.nih.gov/35339490
Autor:
Xuemei Cao, Aziz Sancar, Yanyan Yang, Courtney M. Vaughn, Laura A. Lindsey-Boltz, Zhenxing Liu, Christopher P. Selby, David S. Hsu
Publikováno v:
The Journal of Biological Chemistry
The circadian clock controls the expression of nearly 50% of protein coding genes in mice and most likely in humans as well. Therefore, disruption of the circadian clock is presumed to have serious pathological effects including cancer. However, epid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e49edc2ffc8d16d431ea8717b422648
http://europepmc.org/articles/PMC8403766
http://europepmc.org/articles/PMC8403766
Publikováno v:
J Biol Chem
Previous work with the classic T4 endonuclease V digestion of DNA from irradiated Drosophila cells followed by Southern hybridization led to the conclusion that Drosophila lacks transcription-coupled repair (TCR). This conclusion was reinforced by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb9c823e6f3980e74b28533b4387c20
https://doi.org/10.1074/jbc.ac119.011448
https://doi.org/10.1074/jbc.ac119.011448