Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christopher P. McCabe"'
Autor:
Christopher V McCabe, Peter D Price, Gemma F Codner, Alasdair J Allan, Adam Caulder, Skevoulla Christou, Jorik Loeffler, Matthew Mackenzie, Elke Malzer, Joffrey Mianné, Krystian J Nowicki, Edward J O'Neill, Fran J Pike, Marie Hutchison, Benoit Petit-Demoulière, Michelle E Stewart, Hilary Gates, Sara Wells, Nicholas D Sanderson, Lydia Teboul
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1011187 (2024)
BackgroundRecent developments in CRISPR/Cas9 genome-editing tools have facilitated the introduction of precise alleles, including genetic intervals spanning several kilobases, directly into the embryo. However, the introduction of donor templates, vi
Externí odkaz:
https://doaj.org/article/bb312da1ed8649b9bf1f17a2c3bba609
Autor:
Julia Ramírez-Moya, León Wert-Lamas, Adrián Acuña-Ruíz, Alice Fletcher, Carlos Wert-Carvajal, Christopher J. McCabe, Pilar Santisteban, Garcilaso Riesco-Eizaguirre
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Thyroid cancer is the most common primary endocrine malignancy in adults and its incidence is rapidly increasing. Long non-coding RNAs (lncRNAs), generally defined as RNA molecules longer than 200 nucleotides with no protein-encoding capacit
Externí odkaz:
https://doaj.org/article/c28b93dd23654d67a6e525026b10e771
Autor:
Riazul Zannat, Jonathan Lee, Jameel Muzaffar, Martin L. Read, Katie Brookes, Neil Sharma, Kristien Boelaert, Christopher J. McCabe, Hannah R. Nieto
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionRadioactive iodine (RAI) therapy is a critical component in the post-surgical management of thyroid cancer patients, as well as being a central therapeutic option in the treatment of hyperthyroidism. Previous work suggests that antithyroi
Externí odkaz:
https://doaj.org/article/b7b8f22aaf5a4010b7313cb20ff1f991
Autor:
Roseina Woods, Samuel T. Turvey, Selina Brace, Christopher V. McCabe, Love Dalén, Emily J. Rayfield, Mark J. F. Brown, Ian Barnes
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The Caribbean offers a unique opportunity to study evolutionary dynamics in insular mammals. However, the recent extinction of most Caribbean non-volant mammals has obstructed evolutionary studies, and poor DNA preservation associ
Externí odkaz:
https://doaj.org/article/e8db375df5204778bd30f8e2f11dd6cb
Autor:
Gemma F. Codner, Joffrey Mianné, Adam Caulder, Jorik Loeffler, Rachel Fell, Ruairidh King, Alasdair J. Allan, Matthew Mackenzie, Fran J. Pike, Christopher V. McCabe, Skevoulla Christou, Sam Joynson, Marie Hutchison, Michelle E. Stewart, Saumya Kumar, Michelle M. Simon, Loranne Agius, Quentin M. Anstee, Kirill E. Volynski, Dimitri M. Kullmann, Sara Wells, Lydia Teboul
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background Recent advances in clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) genome editing have led to the use of long single-stranded DNA (lssDNA) molecules for generating conditional
Externí odkaz:
https://doaj.org/article/ee1cca96cdab4bc9a1b2e27269d0610a
Autor:
Jonathan M. Fussey, Jennifer L. Bryant, Nikolaos Batis, Rachael J. Spruce, Andrew Hartley, James S. Good, Christopher J. McCabe, Kristien Boelaert, Neil Sharma, Hisham Mehanna
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
BackgroundCell-free DNA (cfDNA) can be detected in the circulation of healthy individuals, but is found in higher concentrations in cancer patients. Furthermore, mutations in tumor cells can be identified in circulating DNA fragments. This has been t
Externí odkaz:
https://doaj.org/article/27a267a97ef7472e850486a5924d5c73
Autor:
Elisavet Vasilopoulou, Laurence S Loubière, Heike Heuer, Marija Trajkovic-Arsic, Veerle M Darras, Theo J Visser, Gendie E Lash, Guy S Whitley, Christopher J McCabe, Jayne A Franklyn, Mark D Kilby, Shiao Y Chan
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65402 (2013)
Monocarboxylate transporter 8 (MCT8) is a well-established thyroid hormone (TH) transporter. In humans, MCT8 mutations result in changes in circulating TH concentrations and X-linked severe global neurodevelopmental delay. MCT8 is expressed in the hu
Externí odkaz:
https://doaj.org/article/acb0131e384246868b4b0c60476ad8d3
Autor:
Michael H. Robinson, Clark R. Alexander, Chester W. Jackson, Christopher P. McCabe, David Crass
Publikováno v:
Geoarchaeology. 25:312-326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0d9a033637941cbbc3e63750a1ae5ea
https://doi.org/10.1002/gea.20309
https://doi.org/10.1002/gea.20309