Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Christopher P. Marshall"'
Autor:
Sonal V. Gidwani, Devarshi Brahmbhatt, Aaron Zomback, Mamie Bassie, Jennifer Martinez, Jian Zhuang, John Schulze, Jason S. McLellan, Roberto Mariani, Peter Alff, Daniela Frasca, Bonnie B. Blomberg, Christopher P. Marshall, Mark A. Yondola
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral fusion proteins facilitate cellular infection by fusing viral and cellular membranes, which involves dramatic transitions from their pre- to postfusion conformations. These proteins are among the most protective viral immunogens, but t
Externí odkaz:
https://doaj.org/article/9f64bc085d664e7cb563be6d97f3ebf8
Autor:
Katherine M. Eichinger, Jessica L. Kosanovich, Timothy N. Perkins, Tim D. Oury, Nikolai Petrovsky, Christopher P. Marshall, Mark A. Yondola, Kerry M. Empey
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Respiratory syncytial virus (RSV) remains the most common cause of lower respiratory tract infections in children worldwide. Development of a vaccine has been hindered due the risk of enhanced respiratory disease (ERD) following natural RSV exposure
Externí odkaz:
https://doaj.org/article/116afe5507074f2588c9400d0bb46bac
Autor:
Katherine M. Eichinger, Jessica L. Kosanovich, Sonal V. Gidwani, Aaron Zomback, Madeline A. Lipp, Timothy N. Perkins, Tim D. Oury, Nikolai Petrovsky, Christopher P. Marshall, Mark A. Yondola, Kerry M. Empey
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Respiratory syncytial virus (RSV) remains the most common cause of lower respiratory tract infections in children worldwide. Development of a vaccine has been hindered by the risk of developing enhanced respiratory disease (ERD) upon natural exposure
Externí odkaz:
https://doaj.org/article/dc7b75cccbe24d529c8492eb0339ddec
Autor:
Teklab Gebregiworgis, Yoshihito Kano, Jonathan St-Germain, Nikolina Radulovich, Molly L. Udaskin, Ahmet Mentes, Richard Huang, Betty P. K. Poon, Wenguang He, Ivette Valencia-Sama, Claire M. Robinson, Melissa Huestis, Jinmin Miao, Jen Jen Yeh, Zhong-Yin Zhang, Meredith S. Irwin, Jeffrey E. Lee, Ming-Sound Tsao, Brian Raught, Christopher B. Marshall, Michael Ohh, Mitsuhiko Ikura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
SHP2 promotes RAS-driven MAPK signalling, but it is unclear why cancer cells with distinct KRAS mutations exhibit differential sensitivity to SHP2 inhibition. Here the authors show that KRAS Q61H is decoupled from SHP2- mediated upstream regulation,
Externí odkaz:
https://doaj.org/article/adc5eaa39af340409424aef1fcf1144b
Autor:
Nicholas D. Pyenson, Mehsin Al-Ansi, Clare M. Fieseler, Khalid Hassan Al Jaber, Katherine D. Klim, Jacques LeBlanc, Ahmad Mujthaba Dheen Mohamed, Ismail Al-Shaikh, Christopher D. Marshall
Publikováno v:
PeerJ, Vol 10, p e14075 (2022)
One of the largest and least documented populations of dugongs (Dugong dugon) resides in the coastal waters of the United Arab Emirates, and waters surrounding Saudi Arabia, Bahrain, and Qatar. The archaeological record of dugongs in the Gulf Region
Externí odkaz:
https://doaj.org/article/1fe0cbae1a4641fc991ca6deb2dc1b69
Autor:
Christopher W. Marshall, Marcia Kurs-Lasky, Christi L. McElheny, Sophia Bridwell, Hui Liu, Nader Shaikh
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Because some organisms causing urinary tract infection (UTI) may be difficult to culture, examination of bacterial gene sequences in the urine may provide a more accurate view of bacteria present during a UTI. Our objective was to estimate h
Externí odkaz:
https://doaj.org/article/b26f844461964a02bc155ab9a3a76543
Autor:
Catherine R. Armbruster, Christopher W. Marshall, Arkadiy I. Garber, Jeffrey A. Melvin, Anna C. Zemke, John Moore, Paula F. Zamora, Kelvin Li, Ian L. Fritz, Christopher D. Manko, Madison L. Weaver, Jordan R. Gaston, Alison Morris, Barbara Methé, William H. DePas, Stella E. Lee, Vaughn S. Cooper, Jennifer M. Bomberger
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109829- (2021)
Summary: Pseudomonas aeruginosa notoriously adapts to the airways of people with cystic fibrosis (CF), yet how infection-site biogeography and associated evolutionary processes vary as lifelong infections progress remains unclear. Here we test the hy
Externí odkaz:
https://doaj.org/article/49c55f56b39949d0b3f4fb82ffc0cac2
Autor:
Matthew M. Schaefers, Benjamin X. Wang, Nicole M. Boisvert, Sarah J. Martini, Sarah L. Bonney, Christopher W. Marshall, Michael T. Laub, Vaughn S. Cooper, Gregory P. Priebe
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Bacteria in the Burkholderia cepacia complex (BCC) are significant pathogens for people with cystic fibrosis (CF) and are often extensively antibiotic resistant. Here, we assess the impacts of clinically observed mutations in fixL, which enc
Externí odkaz:
https://doaj.org/article/88328d92cfad4f739694303eb8e53448
Autor:
Yoshihito Kano, Teklab Gebregiworgis, Christopher B. Marshall, Nikolina Radulovich, Betty P. K. Poon, Jonathan St-Germain, Jonathan D. Cook, Ivette Valencia-Sama, Benjamin M. M. Grant, Silvia Gabriela Herrera, Jinmin Miao, Brian Raught, Meredith S. Irwin, Jeffrey E. Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming-Sound Tsao, Mitsuhiko Ikura, Michael Ohh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Deregulation of the RAS GTPase cycle due to mutations in RAS genes is commonly associated with cancer development. Here authors use NMR and mass spectrometry to shows that KRAS phosphorylation via Src alters the conformation of switch I and II region
Externí odkaz:
https://doaj.org/article/811fdf81e7164853822f6750cc8b6260
Publikováno v:
mSystems, Vol 5, Iss 5 (2020)
ABSTRACT Acetogens are anaerobic bacteria capable of fixing CO2 or CO to produce acetyl coenzyme A (acetyl-CoA) and ultimately acetate using the Wood-Ljungdahl pathway (WLP). Acetobacterium woodii is the type strain of the Acetobacterium genus and ha
Externí odkaz:
https://doaj.org/article/3cbf8633f2474f17b610b9d65d4e550a