Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Christopher P. Dillon"'
Autor:
Pratyusha Mandal, Lynsey N. Nagrani, Liliana Hernandez, Anita Louise McCormick, Christopher P. Dillon, Heather S. Koehler, Linda Roback, Emad S. Alnemri, Douglas R. Green, Edward S. Mocarski
Publikováno v:
Viruses, Vol 13, Iss 9, p 1707 (2021)
Programmed cell death pathways eliminate infected cells and regulate infection-associated inflammation during pathogen invasion. Cytomegaloviruses encode several distinct suppressors that block intrinsic apoptosis, extrinsic apoptosis, and necroptosi
Externí odkaz:
https://doaj.org/article/f06cb379cd384a1fb21784dffe00b61d
Autor:
Ricardo Weinlich, Andrew Oberst, Christopher P. Dillon, Laura J. Janke, Sandra Milasta, John R. Lukens, Diego A. Rodriguez, Prajwal Gurung, Chandra Savage, Thirumala D. Kanneganti, Douglas R. Green
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 340-348 (2013)
Caspase-8 or cellular FLICE-like inhibitor protein (cFLIP) deficiency leads to embryonic lethality in mice due to defects in endothelial tissues. Caspase-8−/− and receptor-interacting protein kinase-3 (RIPK3)−/−, but not cFLIP−/− and RIPK
Externí odkaz:
https://doaj.org/article/ab6fdc9635da46a3b9b445a0ce2bf653
Autor:
Christopher P. Dillon, Andrew Oberst, Ricardo Weinlich, Laura J. Janke, Tae-Bong Kang, Tehila Ben-Moshe, Tak W. Mak, David Wallach, Douglas R. Green
Publikováno v:
Cell Reports, Vol 1, Iss 5, Pp 401-407 (2012)
Caspase-8, the initiator caspase of the death receptor pathway of apoptosis, its adapter molecule, FADD, required for caspase-8 activation, and cFLIPL, a caspase-8-like protein that lacks a catalytic site and blocks caspase-8-mediated apoptosis, are
Externí odkaz:
https://doaj.org/article/bd24a9255c53497a85dbca199386b536
Autor:
Shahram Salek-Ardakani, John C. Lin, Arvind Rajpal, Eugenia Kraynov, Jeffrey Chou, Jerry D. Clark, Allison Xu, Christopher P. Dillon, Natalija Budimir, Brent Kern, Bart Jessen, Cris Kamperschroer, Sherman M. Chin, Christopher R. Kimberlin, Joyce Chou, HoangKim Nguyen, Yasmina Abdiche, Sawsan Youssef, Amir A. Al-Khami
Supplementary Figure 10 shows the selectivity of sasanlimab binding to human and cynomolgus monkey PD-1 using HEK-293T transiently transfected cells and flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570baa904bc39c4217dce06d7f70f261
https://doi.org/10.1158/1535-7163.22521613.v1
https://doi.org/10.1158/1535-7163.22521613.v1
Autor:
Manfred Kraus, Joseph Tumang, Xianxian Zheng, Li-Chin Yao, Martin Wythes, Benoit J. Van den Eynde, Konstantinos Tsaparikos, Vince R. Torti, Nicole Streiner, Chad Ray, Virginie Rabolli, Romain Pirson, Nichol Miller, Reece Marillier, Karen Maegley, Wenlin Li, Marie-Claire Letellier, Jie Guo, Valeria R. Fantin, Christopher P. Dillon, Sofie Denies, Deepak Dalvie, Stefano Crosignani, Sandra Cauwenberghs, Danying Cai, Derek Bartlett, Gregory Driessens, Bruno Gomes
Table S2 shows a selectivity screen of PF-06840003 in in vitro pharmacological assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47698983ea67ec47db744f5010daf12a
https://doi.org/10.1158/1535-7163.22505134
https://doi.org/10.1158/1535-7163.22505134
Autor:
Thomas A. Paul, Martin Wythes, Fen Wang, Michelle Tran-Dube, Stephanie Scales, Eugene Rui, Ryan L. Patman, Wei Liu, Robert A. Kumpf, Susan E. Kephart, Vesta Goshtasbi, Ya-Li Deng, Alexei Brooun, John Braganza, Prakash Palde, Shannon Karlicek Bryant, Elizabeth A. McMillan, Chi-Yeh Chung, John Sherrill, Hieu Lam, Eleanore Hendrickson, Natalie Miller, Amy Nemeth, Manli Shi, Noah Spiegel, Shinji Yamazaki, Yuli Wang, Christopher P. Dillon, Tao Xie, Michele McTigue, Indrawan J. McAlpine, Karen A. Maegley, John Tatlock, Kristen Jensen-Pergakes
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46922fa072a5bd8d00c642d9ca4b1236
https://doi.org/10.1158/1535-7163.22522828.v1
https://doi.org/10.1158/1535-7163.22522828.v1
Autor:
Thomas A. Paul, Martin Wythes, Fen Wang, Michelle Tran-Dube, Stephanie Scales, Eugene Rui, Ryan L. Patman, Wei Liu, Robert A. Kumpf, Susan E. Kephart, Vesta Goshtasbi, Ya-Li Deng, Alexei Brooun, John Braganza, Prakash Palde, Shannon Karlicek Bryant, Elizabeth A. McMillan, Chi-Yeh Chung, John Sherrill, Hieu Lam, Eleanore Hendrickson, Natalie Miller, Amy Nemeth, Manli Shi, Noah Spiegel, Shinji Yamazaki, Yuli Wang, Christopher P. Dillon, Tao Xie, Michele McTigue, Indrawan J. McAlpine, Karen A. Maegley, John Tatlock, Kristen Jensen-Pergakes
ElasticNet Tables for PF-06939999 in NSCLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2702f62418df5f02af2f23bc6d583fa7
https://doi.org/10.1158/1535-7163.22522837
https://doi.org/10.1158/1535-7163.22522837
Autor:
Thomas A. Paul, Martin Wythes, Fen Wang, Michelle Tran-Dube, Stephanie Scales, Eugene Rui, Ryan L. Patman, Wei Liu, Robert A. Kumpf, Susan E. Kephart, Vesta Goshtasbi, Ya-Li Deng, Alexei Brooun, John Braganza, Prakash Palde, Shannon Karlicek Bryant, Elizabeth A. McMillan, Chi-Yeh Chung, John Sherrill, Hieu Lam, Eleanore Hendrickson, Natalie Miller, Amy Nemeth, Manli Shi, Noah Spiegel, Shinji Yamazaki, Yuli Wang, Christopher P. Dillon, Tao Xie, Michele McTigue, Indrawan J. McAlpine, Karen A. Maegley, John Tatlock, Kristen Jensen-Pergakes
Supplemental Figures S1-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37771825e5ee666377a34886744f4a83
https://doi.org/10.1158/1535-7163.22522831
https://doi.org/10.1158/1535-7163.22522831
Autor:
Shahram Salek-Ardakani, John C. Lin, Arvind Rajpal, Eugenia Kraynov, Jeffrey Chou, Jerry D. Clark, Allison Xu, Christopher P. Dillon, Natalija Budimir, Brent Kern, Bart Jessen, Cris Kamperschroer, Sherman M. Chin, Christopher R. Kimberlin, Joyce Chou, HoangKim Nguyen, Yasmina Abdiche, Sawsan Youssef, Amir A. Al-Khami
Development of antagonistic mAbs that specifically target the immune checkpoint receptor, programmed cell death protein-1 (PD-1), is of great interest for cancer immunotherapy. Here, we report the biophysical characteristics and nonclinical antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a605a4f9fbc692ff14dc6e0fb35295da
https://doi.org/10.1158/1535-7163.c.6543064
https://doi.org/10.1158/1535-7163.c.6543064
Autor:
Manfred Kraus, Joseph Tumang, Xianxian Zheng, Li-Chin Yao, Martin Wythes, Benoit J. Van den Eynde, Konstantinos Tsaparikos, Vince R. Torti, Nicole Streiner, Chad Ray, Virginie Rabolli, Romain Pirson, Nichol Miller, Reece Marillier, Karen Maegley, Wenlin Li, Marie-Claire Letellier, Jie Guo, Valeria R. Fantin, Christopher P. Dillon, Sofie Denies, Deepak Dalvie, Stefano Crosignani, Sandra Cauwenberghs, Danying Cai, Derek Bartlett, Gregory Driessens, Bruno Gomes
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f74526ae85eebdbe19c754931a606d3
https://doi.org/10.1158/1535-7163.22505140
https://doi.org/10.1158/1535-7163.22505140