Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher P. Bonin"'
Autor:
Geneva Hargis, Tingting Xu, An Xiaofei, Ke Zhang, Jianling Tao, Silvia Liu, Yuchen Pan, Mark S. Wang, Yanlin Wang, Lu Zhang, Yi Qiao, Tao Huan, Dong Zhou, Yanjiao Zhou, Rong Zhang, Yanbao Yu, Liangxiang Xiao, Xiao-Jun Tian, Liu Shijia, Haiyan Fu, Yuan Gui, Donald L. Kreutzer, Christopher P. Bonin, Ying Yu
Publikováno v:
Molecular Metabolism, Vol 54, Iss, Pp 101367-(2021)
Molecular Metabolism
Molecular Metabolism
Objective Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. Our study proposes to evaluate
Autor:
Yanbao Yu, Silvia Liu, Yanlin Wang, Yanjiao Zhou, Yi Qiao, Youhua Liu, Yuanyuan Wang, Rong Zhang, Haiyan Fu, Yuan Gui, Sheldon I. Bastacky, Dong Zhou, Donald L. Kreutzer, Partha S. Biswas, Xiao-Jun Tian, Geneva Hargis, Christopher P. Bonin
Publikováno v:
iScience
iScience, Vol 24, Iss 10, Pp 103112-(2021)
iScience, Vol 24, Iss 10, Pp 103112-(2021)
Summary The kidney local microenvironment (KLM) plays a critical role in the pathogenesis of kidney fibrosis. However, the composition and regulation of a fibrotic KLM remain unclear. Through a multidisciplinary approach, we investigated the roles of
Autor:
Ye F Tian, Anthony T. Vella, Beiyan Zhou, Antoine Ménoret, Brian R. Gastman, C. Marcela Diaz-Montero, Annabelle Rodriguez, Michael Cartwright, Samjhana Thapaliya, Chuan Li, Jung-Min Song, Cheryl M. Cameron, Banumathi Tamilselvan, Pauline Funchain, Christopher P. Bonin, Keaton Karlinsey, Mark J. Cameron, Yee Peng Phoon, Alyssa Matz, Jackelyn B. Golden, Lili Qu, Angkana Thongkum
Publikováno v:
The Journal of experimental medicine. 219(1)
Immune checkpoint inhibitor (ICI) therapy continues to revolutionize melanoma treatment, but only a subset of patients respond. Major efforts are underway to develop minimally invasive predictive assays of ICI response. Using single-cell transcriptom
Autor:
Mark J. Cameron, Ye Tian, Cheryl M. Cameron, Beiyan Zhou, Keaton Karlinsey, C. Marcela Diaz-Montero, Antoine Ménoret, Brian R. Gastman, Pauline Funchain, Anthony T. Vella, Yee Peng Phoon, Samjhana Thapaliya, Jung-Min Song, Christopher P. Bonin, Chuan Li, Lili Qu, Annabelle Rodriguez
Publikováno v:
Poster Presentations.
Background Immune checkpoint blockade (ICB) has greatly advanced the treatment of melanoma. A key component of ICB is the stimulation of CD8+ T cells in the tumor. However, ICB therapy only benefits a subset of patients and a reliable prediction meth
Autor:
Beiyan Zhou, Christopher P. Bonin, Chuan Li, Anthony T. Vella, Cullen Farragher, Antoine Ménoret, Paul Holvoet, Zhengqing Ouyang
Adipose tissue macrophages (ATM) are crucial for maintaining adipose tissue homeostasis and mediating obesity-induced metabolic abnormalities, including prediabetic conditions and type 2 diabetes mellitus. Despite their key functions in regulating ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77004bb9383c7c12b2fe25c20078e356
https://lirias.kuleuven.be/handle/123456789/647142
https://lirias.kuleuven.be/handle/123456789/647142
Autor:
Don C. Anstrom, Sara Salvador, Santanu Dasgupta, Christopher P. Bonin, Robert L. D'ordine, Dave Warner, Stephanie Back, Martin Stoecker, Michael H. Luethy, Jacqueline E. Heard, Mark S. Abad, Santiago X. Navarro, Ganesh Kumar, Robert J. Bensen, Jayaprakash Targolli, Paolo Castiglioni, Mary Fernandes, Jay M. Harrison
Publikováno v:
Plant Physiology. 147:446-455
Limited available water is the single most important factor that reduces global crop yields, with far reaching socioeconomic implications. In North America alone, it is estimated that 40% of yearly maize ( Zea mays ) crop losses are due to suboptimal
Publikováno v:
Developmental Dynamics. 234:613-621
Mammalian autonomic nervous system (ANS) development requires the combinatorial action of a number of transcription factors, which include Mash 1, Phox 2b, and GATA 3. Here we show that the bHLH transcription factor, Hand 2 (dHAND), is expressed conc
Publikováno v:
Journal of Neuroscience Research. 76:613-622
HAND2 (also known as dHAND) is a basic helix-loop-helix (bHLH) transcription factor essential for development of the heart, limbs, and neural crest-derived lineages. HAND2 expression is observed in a number of tissues derived from the neural crest, i
Publikováno v:
Biochemistry. 41:15578-15589
GDP-D-mannose 4,6-dehydratase catalyzes the first step in the de novo synthesis of GDP-L- fucose, the activated form of L-fucose, which is a component of glycoconjugates in plants known to be important to the development and strength of stem tissues.
Autor:
Paolo Castiglioni, Robert E. Sharp, Margaret A. Nemeth, Marie Coffin, Rebecca A. Silady, Donald E. Nelson, Donald Anstrom, Mark Lawson, Joy E. Whitsel, Frank G. Dohleman, William R. Reeves, David E. Clay, Krishna S. Nemali, Bernard Sammons, Christopher P. Bonin, Mark E. Leibman, Osric Rahul Patharkar, Mike Stephens, Michael H. Luethy
Publikováno v:
Plant, cellenvironment. 38(9)
Maize (Zea mays ssp. mays L.) is highly susceptible to drought stress. This work focused on whole-plant physiological mechanisms by which a biotechnology-derived maize event expressing bacterial cold shock protein B (CspB), MON 87460, increased grain