Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Christopher P Morris"'
Autor:
Dilek Guneri, Effrosyni Alexandrou, Kamel El Omari, Zuzana Dvořáková, Rupesh V. Chikhale, Daniel T. S. Pike, Christopher A. Waudby, Christopher J. Morris, Shozeb Haider, Gary N. Parkinson, Zoë A. E. Waller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The insulin-linked polymorphic region is a variable number of tandem repeats region of DNA in the promoter of the insulin gene that regulates transcription of insulin. This region is known to form the alternative DNA structures, i-motifs and
Externí odkaz:
https://doaj.org/article/f3133e77e6154bdd947d113634a42cc4
Autor:
Jake Brooks, James Everett, Emily Hill, Kharmen Billimoria, Christopher M. Morris, Peter J. Sadler, Neil Telling, Joanna F. Collingwood
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-7 (2024)
Abstract Neuromelanin-pigmented neurons of the substantia nigra are selectively lost during the progression of Parkinson’s disease. These neurons accumulate iron in the disease state, and iron-mediated neuron damage is implicated in cell death. Ani
Externí odkaz:
https://doaj.org/article/63afa146f787477b8ee42d09a8905646
Autor:
Christopher J. Morris, Michael G. Rolf, Linda Starnes, Inmaculada C. Villar, Amy Pointon, Holly Kimko, Giovanni Y. Di Veroli
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Pharmaceutical companies routinely screen compounds for hemodynamics related safety risk. In vitro secondary pharmacology is initially used to prioritize compounds while in vivo studies are later used to quantify and translate risk to humans. This st
Externí odkaz:
https://doaj.org/article/8cc8e9c9676f413cbf55bed31991df2d
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 8, p e0004034 (2015)
Externí odkaz:
https://doaj.org/article/52102bcd1e5a493f9307766a71f41243
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003932 (2015)
Filariae are tissue-invasive nematodes that cause diseases such as elephantiasis and river blindness. The goal of this study was to characterize the role of histamine during Litomosoides sigmodontis infection of BALB/c mice, a murine model of filaria
Externí odkaz:
https://doaj.org/article/39cdc6a1286741e0935b4d6e2130037b
Publikováno v:
JID Innovations, Vol 4, Iss 4, Pp 100283- (2024)
The skin is a multifunctional organ, forming a barrier between the external and internal environment, thereby functioning as a safeguard against extrinsic factors. Autophagy has been implicated in epidermal differentiation and in preserving skin home
Externí odkaz:
https://doaj.org/article/782a162258df4f87b4a950cf06656402
Autor:
Marc P Hübner, Kristin E Killoran, Michael Rajnik, Samuel Wilson, Kevin C Yim, Marina N Torrero, Christopher P Morris, Boris Nikonenko, Jorge C G Blanco, Val G Hemming, Edward Mitre
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1970 (2012)
Chronic helminth infections induce a Th2 immune shift and establish an immunoregulatory milieu. As both of these responses can suppress Th1 immunity, which is necessary for control of Mycobacterium tuberculosis (MTB) infection, we hypothesized that c
Externí odkaz:
https://doaj.org/article/91af0db8809348e4890ab2cfcc92868c
Autor:
Julie A. Bradley, MD, Xiaoying Liang, PhD, Raymond B. Mailhot Vega, MD, MPH, Chunbo Liu, PhD, Eric D. Brooks, MD, Teena Burchianti, ARNP, Emma Viviers, MS, Roi Dagan, MD, MS, Oluwadamilola T. Oladeru, MD, MA, MBA, Christopher G. Morris, MS, Nancy P. Mendenhall, MD
Publikováno v:
International Journal of Particle Therapy, Vol 9, Iss 4, Pp 269-278 (2023)
Purpose: To determine the rib fracture rate in a cohort of patients with breast cancer treated with proton therapy. Patient and Methods: From a prospective database, we identified 225 patients treated with proton therapy between 2012 and 2020 (223 wo
Externí odkaz:
https://doaj.org/article/d3e5fc85fd7c428aadf2996f42a03e7b
Autor:
Michael S. Rutenberg, MD, PhD, Bradford S. Hoppe, MD, MPH, Jason S. Starr, DO, Ziad Awad, MD, Mathew Thomas, MBBS, MD, Christopher G. Morris, MS, Perry Johnson, PhD, Randal H. Henderson, MD, MBA, Jeremy C. Jones, MD, Bharatsinh Gharia, MBBS, MD, Steven Bowers, MD, Herbert C. Wolfsen, MD, Sunil Krishnan, MBBS, MD, Stephen J. Ko, MD, Hani M. Babiker, MD, Romaine C. Nichols, Jr, MD
Publikováno v:
International Journal of Particle Therapy, Pp 18-29 (2022)
Purpose: When treating esophageal cancer with radiation therapy, it is critical to limit the dose to surrounding structures, such as the lung and/or heart, as much as possible. Proton radiation therapy allows a reduced radiation dose to both the hear
Externí odkaz:
https://doaj.org/article/6e0ce34c85cc410c8a3e146ab69d68ad
Autor:
Raymond B. Mailhot Vega, Beatriz E. Garcia Robles, Christopher G. Morris, Kara Buss, Ulises Mejia, Adela Poitevin, Maria Fatima Chilaca Rosas, Heynar Perez Villanueva, Jesus Armando Felix Leyva, Daniel J. Indelicato, Dolores De la Mata
Publikováno v:
JCO Global Oncology, Vol , Iss 9 (2023)
PURPOSEMexico and Central America have the highest childhood cancer incidence in the West. Pediatric-specific oncology knowledge contributes to the disparity. We sought to (1) determine the self-identified treatment patterns and needs of Mexican pedi
Externí odkaz:
https://doaj.org/article/484ab3a2adbd4ef095751686658a183b