Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Christopher P, Chen"'
Autor:
Vismitha Rajeev, Nishat I. Tabassum, David Y. Fann, Christopher P. Chen, Mitchell K.P. Lai, Thiruma V. Arumugam
Publikováno v:
Journal of Obesity & Metabolic Syndrome, Vol 33, Iss 2, Pp 92-107 (2024)
Intermittent fasting (IF), a dietary pattern alternating between eating and fasting periods within a 24-hour cycle, has garnered recognition for its potential to enhance both healthspan and lifespan in animal models and humans. It also shows promise
Externí odkaz:
https://doaj.org/article/dd50f72992a84704a4ce98f31788f6e6
Autor:
Keith A. Gagnon, Jessie Huang, Olivia T. Hix, Veronica W. Hui, Anne Hinds, Esther Bullitt, Jeroen Eyckmans, Darrell N. Kotton, Christopher S. Chen
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026126-026126-13 (2024)
Previous lung-on-chip devices have facilitated significant advances in our understanding of lung biology and pathology. Here, we describe a novel lung-on-a-chip model in which human induced pluripotent stem cell-derived alveolar epithelial type II ce
Externí odkaz:
https://doaj.org/article/156561785503486e81a4ba15a22d4b49
Autor:
Shao-Hen Chiew, Kilian Poirier, Rajesh Mishra, Ulrike Bornheimer, Ewan Munro, Si Han Foon, Christopher Wanru Chen, Wei Sheng Lim, Chee Wei Nga
Publikováno v:
IEEE Transactions on Quantum Engineering, Vol 5, Pp 1-19 (2024)
Multiobjective optimization is a ubiquitous problem that arises naturally in many scientific and industrial areas. Network routing optimization with multiobjective performance demands falls into this problem class, and finding good quality solutions
Externí odkaz:
https://doaj.org/article/ac2c5a347a784832883342a7c3216ac2
Autor:
Xin Ying Chua, Federico Torta, Joyce R. Chong, Narayanaswamy Venketasubramanian, Saima Hilal, Markus R. Wenk, Christopher P. Chen, Thiruma V. Arumugam, Deron R. Herr, Mitchell K. P. Lai
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Alzheimer’s disease (AD) and vascular dementia (VaD) are two of the commonest causes of dementia in the elderly. Of the myriad biomolecules implicated in dementia pathogenesis, sphingolipids have attracted relatively scant resea
Externí odkaz:
https://doaj.org/article/504a7fb1e0244d43871ae662fd979401
Autor:
Joyce R. Chong, Yuek Ling Chai, Amelia T. Y. Yam, Saima Hilal, Henri Vrooman, Narayanaswamy Venketasubramanian, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Christopher P. Chen, Mitchell K. P. Lai
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION While elevated blood glial fibrillary acidic protein (GFAP) has been associated with brain amyloid pathology, whether this association occurs in populations with high cerebral small vessel disease (CSVD) concomitance remains unc
Externí odkaz:
https://doaj.org/article/847dff28cdd24ebbb6c6125076d11e68
Autor:
Teodor E. Yordanov, Mikaela S. Keyser, Marco A. Enriquez Martinez, Tyron Esposito, Juliann B. Tefft, Elysse K. Morris, Larisa I. Labzin, Samantha J. Stehbens, Alan E. Rowan, Benjamin M. Hogan, Christopher S. Chen, Jan Lauko, Anne K. Lagendijk
Publikováno v:
APL Bioengineering, Vol 8, Iss 1, Pp 016108-016108-14 (2024)
Cerebral cavernous malformations (CCMs) are vascular lesions that predominantly form in blood vessels of the central nervous system upon loss of the CCM multimeric protein complex. The endothelial cells within CCM lesions are characterized by overact
Externí odkaz:
https://doaj.org/article/a60ddf22761145ba8d3826e7dbcf0896
Autor:
Vismitha Rajeev, Yuek Ling Chai, Luting Poh, Sharmelee Selvaraji, David Y. Fann, Dong-Gyu Jo, T. Michael De Silva, Grant R. Drummond, Christopher G. Sobey, Thiruma V. Arumugam, Christopher P. Chen, Mitchell K. P. Lai
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically involved in cognitive processes must feature as the main
Externí odkaz:
https://doaj.org/article/04bdcb4ece6c4c74836318eba6c538d7
Autor:
Yuek Ling Chai, Jasinda H. Lee, Joyce R. Chong, Clive Ballard, Paul T. Francis, Brian K. Kennedy, Thiruma V. Arumugam, Christopher P. Chen, Dag Aarsland, Mitchell K. P. Lai
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Chronically dysregulated neuroinflammation has been implicated in neurodegenerative dementias, with separate studies reporting increased brain levels of inflammatory mediators and gliosis in Alzheimer’s disease (AD) as well as i
Externí odkaz:
https://doaj.org/article/2a5cf1b0ed4d4f41a68dd14770553323
Autor:
J. Matthijs Biesbroek, Nick A Weaver, Hugo P Aben, Hugo J Kuijf, Jill Abrigo, Hee-Joon Bae, Mélanie Barbay, Jonathan G Best, Régis Bordet, Francesca M. Chappell, Christopher P.L.H. Chen, Thibaut Dondaine, Ruben S. van der Giessen, Olivier Godefroy, Jules Verne, Bibek Gyanwali, Olivia K.L. Hamilton, Saima Hilal, Irene M.C. Huenges Wajer, Yeonwook Kang, L. Jaap Kappelle, Beom Joon Kim, Sebastian Köhler, Paul L.M. de Kort, Peter J. Koudstaal, Gregory Kuchcinski, Bonnie Y.K. Lam, Byung-Chul Lee, Keon-Joo Lee, Jae-Sung Lim, Renaud Lopes, Stephen D.J. Makin, Anne-Marie Mendyk, Vincent C.T. Mok, Mi Sun Oh, Robert J. van Oostenbrugge, Martine Roussel, Lin Shi, Julie Staals, Maria del C. Valdés-Hernández, Narayanaswamy Venketasubramanian, Frans R.J. Verhey, Joanna M. Wardlaw, David J. Werring, Xu Xin, Kyung-Ho Yu, Martine J.E. van Zandvoort, Lei Zhao, Geert Jan Biessels
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100054- (2024)
Externí odkaz:
https://doaj.org/article/323d321a2e8f4526aa8118b2b8037217
Autor:
Hiba Kobeissi, Javiera Jilberto, M Çağatay Karakan, Xining Gao, Samuel J DePalma, Shoshana L Das, Lani Quach, Jonathan Urquia, Brendon M Baker, Christopher S Chen, David Nordsletten, Emma Lejeune
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0298863 (2024)
Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential opportuni
Externí odkaz:
https://doaj.org/article/b74873e42d354457bd949569e3768cc8