Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Christopher Niyibizi"'
Publikováno v:
Journal of Bone and Mineral Metabolism. 37:773-779
Mutations in Serpinf1 gene which encodes pigment epithelium-derived factor (PEDF) lead to osteogenesis imperfecta type VI whose hallmark is defective matrix mineralization. We reported previously that PEDF reduced expression and synthesis of Sost/Scl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8efea0b4e5afbcd4ad317fed56bf2e8
https://doi.org/10.1007/s00774-018-0982-4
https://doi.org/10.1007/s00774-018-0982-4
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3449-3458
Mutations in Serpinf1 gene which encodes pigment epithelium derived factor (PEDF) lead to osteogenesis imperfecta type VI whose hallmark is defective mineralization. We reported that PEDF suppressed expression of Sost/Sclerostin and other osteocyte r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec840ebf78622a13f671596783f4be0
https://doi.org/10.1016/j.bbadis.2018.07.034
https://doi.org/10.1016/j.bbadis.2018.07.034
Publikováno v:
Biochemical and Biophysical Research Communications. 478:1106-1110
Pigment epithelium-derived factor (PEDF) encoded by serpinf1 is a potent anti-angiogenic factor found in a wide variety of fetal and adult tissues. Several reports have shown that lack of PEDF leads to osteogenesis imperfecta (OI) type VI whose hallm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abff264f152cca162c42766e7334566a
https://doi.org/10.1016/j.bbrc.2016.08.076
https://doi.org/10.1016/j.bbrc.2016.08.076
Autor:
Feng Li, Christopher Niyibizi
Publikováno v:
Cells Tissues Organs. 201:14-25
Introduction: Cell therapies for generalized musculoskeletal diseases would require distribution of cells to all the skeletal tissues; however, there are controversies regarding the transplantability of multipotent mesenchymal stems cells (MSCs). We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903af9702b95ee2e0a448073445890df
https://doi.org/10.1159/000438985
https://doi.org/10.1159/000438985
Publikováno v:
Journal of Cellular Physiology. 230:1243-1249
Mutations in Serpinf1 gene which encodes pigment epithelium derived factor (PEDF) lead to osteogenesis imperfecta type VI whose hallmark is defective mineralization. Mechanisms by which PEDF regulates matrix mineralization remain unknown. We examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f9198c180f2487c3eee1bc3c0630e4
https://doi.org/10.1002/jcp.24859
https://doi.org/10.1002/jcp.24859
Publikováno v:
Stem Cells. 31:2714-2723
Pigment epithelium-derived factor (PEDF) is a potent antiangiogenic factor found in a wide variety of tissues. Recent findings indicated that lack of PEDF leads to osteogenesis imperfecta type VI whose hallmark is a defect in mineralization. We inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb8e9ed4c7282c9e426de8538721a52
https://doi.org/10.1002/stem.1505
https://doi.org/10.1002/stem.1505
Publikováno v:
Bone. 47:546-555
Currently, there are conflicting data in literature regarding contribution of bone marrow stromal cells (BMSCs) to bone formation when the cells are systemically delivered in recipient animals. To understand if BMSCs contribute to bone cell phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bfe59079e652f44bb5f104280ba900
https://doi.org/10.1016/j.bone.2010.05.040
https://doi.org/10.1016/j.bone.2010.05.040
Publikováno v:
Journal of Cellular Biochemistry. 109:643-652
Induced pluripotent stem cells (iPSCs) have generated hope and excitement because of the potential they possess for generating patient-specific embryonic-like stem cells (ESCs). Although many hurdles remain to be solved before the cells can be applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19dc4ed15969ad44e66be1bf95e6825
https://doi.org/10.1002/jcb.22440
https://doi.org/10.1002/jcb.22440
Publikováno v:
The Open Stem Cell Journal. 1:54-61
Mesenchymal stem cells have generated much interest because of their potential use in regenerative medicine. The major draw back in the application of these cells is that there is no single marker or markers that have been established to identify and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c84cbda110f9a10a268066b35829e1
https://doi.org/10.2174/1876893800901010054
https://doi.org/10.2174/1876893800901010054
Autor:
Christopher Niyibizi, Feng Li
Publikováno v:
International Journal of Clinical Rheumatology. 4:57-66
Osteogenesis imperfecta (OI) is a brittle-bone disease whose hallmark is bone fragility. Since the disease is genetic, there is currently no available cure. Several pharmacological agents have been tried with not much success, except the recent use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2083c510267cf70bb58aebe1bba0fe
https://doi.org/10.2217/17584272.4.1.57
https://doi.org/10.2217/17584272.4.1.57