Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christopher Nils Mais"'
Autor:
Marie Burt, Georgia Angelidou, Christopher Nils Mais, Christian Preußer, Timo Glatter, Thomas Heimerl, Rüdiger Groß, Javier Serrania, Gowtham Boosarpu, Elke Pogge von Strandmann, Janis A. Müller, Gert Bange, Anke Becker, Mareike Lehmann, Danny Jonigk, Lavinia Neubert, Hinrich Freitag, Nicole Paczia, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract The continuous emergence of multidrug‐resistant bacterial pathogens poses a major global healthcare challenge, with Klebsiella pneumoniae being a prominent threat. We conducted a comprehensive study on K. pneumoniae’s antibiotic resistan
Externí odkaz:
https://doaj.org/article/d578823b51904a85bb20616a75988ddc
Autor:
Laura Czech, Christopher-Nils Mais, Hanna Kratzat, Pinku Sarmah, Pietro Giammarinaro, Sven-Andreas Freibert, Hanna Folke Esser, Joanna Musial, Otto Berninghausen, Wieland Steinchen, Roland Beckmann, Hans-Georg Koch, Gert Bange
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Bacterial responses to nutrient limitation and other stress conditions are often modulated by the nucleotide-based second messenger (p)ppGpp. Here, the authors show that (p)ppGpp inhibits the SRP membrane-protein insertion and secretion pathway by bi
Externí odkaz:
https://doaj.org/article/61ed31ca782f463ca798cb2a7dd3a7ad
Autor:
Tamara Hoffmann, Devid Mrusek, Patricia Bedrunka, Fabiana Burchert, Christopher-Nils Mais, Daniel B. Kearns, Florian Altegoer, Erhard Bremer, Gert Bange
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Biofilm formation in Bacillus subtilis requires expression of matrix production genes, which are upregulated by transcriptional activator RemA. Here, the authors show that RemA forms octameric rings with the potential to form a 16-meric superstructur
Externí odkaz:
https://doaj.org/article/d65f8dc8c4264fadb72b501cc705fb6e
Autor:
Alexandra A. Richter, Christopher-Nils Mais, Laura Czech, Kyra Geyer, Astrid Hoeppner, Sander H. J. Smits, Tobias J. Erb, Gert Bange, Erhard Bremer
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Bacteria frequently adapt to high osmolarity surroundings through the accumulation of compatible solutes. Ectoine is a prominent member of these types of stress protectants and is produced via an evolutionarily conserved biosynthetic pathway beginnin
Externí odkaz:
https://doaj.org/article/2a7437065e37451c9b031a2d68f60425
Publikováno v:
microLife. 4
Dinucleoside polyphosphates, a class of nucleotides found amongst all the Trees of Life, have been gathering a lot of attention in the past decades due to their putative role as cellular alarmones. In particular, diadenosine tetraphosphate (AP4A) has
Autor:
Pietro I. Giammarinaro, Megan K. M. Young, Wieland Steinchen, Christopher-Nils Mais, Georg Hochberg, Jin Yang, David M. Stevenson, Daniel Amador-Noguez, Anja Paulus, Jue D. Wang, Gert Bange
Publikováno v:
Nat Microbiol
Diadenosine tetraphosphate (Ap4A) is a putative second messenger molecule that is conserved from bacteria to humans. Nevertheless, its physiological role and the underlying molecular mechanisms are poorly characterized. We investigated the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd80d4c9178a4b14079dd325c3581dc3
https://hdl.handle.net/21.11116/0000-000A-D9C0-8
https://hdl.handle.net/21.11116/0000-000A-D9C0-8
Autor:
Laura Czech, Florian Altegoer, Christopher-Nils Mais, Andreas Seubert, Lucas Hermann, Erhard Bremer, Alexandra A. Richter, Gert Bange, Isa Wernersbach
Publikováno v:
'Journal of Biological Chemistry ', vol: 295, pages: 9087-9104 (2020)
J Biol Chem
J Biol Chem
When faced with increased osmolarity in the environment, many bacterial cells accumulate the compatible solute ectoine and its derivative 5-hydroxyectoine. Both compounds are not only potent osmostress protectants, but also serve as effective chemica
Autor:
Sonja K. Hühn, Lutz B. Jehn, Gert Bange, Christian Michel, Ying Wang, André Marquardt, Clara Simon, Elisabeth Mack, Christopher-Nils Mais, Lea V. Fritz, Andreas Neubauer, Andreas Burchert, Ellen Wollmer, Jennifer Kremer, Kristina Sohlbach, Cornelia Brendel, Claudia Haferlach, Sabrina Inselmann
Publikováno v:
Haematologica
Autor:
Erhard Bremer, Lucas Hermann, Christopher-Nils Mais, Gert Bange, Laura Czech, Sander H. J. Smits
Publikováno v:
Biological chemistry. 401(12)
Ectoine and its derivative 5-hydroxyectoine are compatible solutes and chemical chaperones widely synthesized byBacteriaand someArchaeaas cytoprotectants during osmotic stress and high- or low-growth temperature extremes. The function-preserving attr
Publikováno v:
Inorganic Chemistry. 57:351-359
Within this study, the synthesis and coordination chemistry of open-chain ligands bearing disila-units is presented. Instead of basic 1:1 complexes, structural diversity was discovered in the variety of ligand and salt. Stable complexes of alkali and