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pro vyhledávání: '"Christopher N. Wilde"'
Autor:
Jason S. Tedrow, Alan M. Allgeier, Jacqueline E. Milne, Bradley J. Shaw, Christopher N. Wilde, Tsang-Lin Hwang
Publikováno v:
Organometallics. 31:519-522
Two stable degradants of palladium tBuXPhos catalyst have been synthesized from tBuXPhos and Pd2(dba)3·CHCl3, isolated, and fully characterized. Complex 2 augments the known literature examples of palladacycles from this ligand family but is present
Autor:
Alan M. Allgeier, Les P. Miranda, Jennifer R. Allen, Vellarkad N. Viswanadhan, Gloria Biddlecome, Randall W. Hungate, Justin K. Murray, Annie Kasparian, Sean Yoder, Chenera Balan, Christopher N. Wilde
Publikováno v:
Journal of Combinatorial Chemistry. 12:676-686
Intracellular levels of the hypoxia-inducible transcription factor (HIF) are regulated under normoxic conditions by prolyl hydroxylases (PHD1, 2, and 3). Treatment of cells with PHD inhibitors stabilizes HIF-1α, eliciting an artificial hypoxic respo