Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christopher N. Ibabao"'
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 308-318 (2015)
In binary cell‐fate decisions, driving one lineage and suppressing the other are conjoined. We have previously reported that aryl hydrocarbon receptor (AhR) promotes retinoic acid (RA)‐induced granulocytic differentiation of lineage bipotent HL
Externí odkaz:
https://doaj.org/article/280634ecf4d94ebcb91d68a329bfb58e
Autor:
Holly A Jensen, Rodica P Bunaciu, Christopher N Ibabao, Rebecca Myers, Jeffrey D Varner, Andrew Yen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98929 (2014)
Emergent resistance can be progressive and driven by global signaling aberrations. All-trans retinoic acid (RA) is the standard therapeutic agent for acute promyelocytic leukemia, but 10-20% of patients are not responsive, and initially responsive pa
Externí odkaz:
https://doaj.org/article/2b866f2ca5ff44e2bfb63eada4752ac5
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 308-318 (2015)
FEBS Open Bio
FEBS Open Bio
Highlights • VAF347 augments RA-induced expression of Vav1, c-Cbl, Lyn, and P47phox. • VAF347 augments RA-induced G0/G1 enrichment. • VAF347 augments RA-induced expression of CD11b integrin receptor. • VAF347 augments RA-induced respiratory b
Publikováno v:
Blood. 122:1836-1836
The identification of critical signaling pathways necessary for the development, maintenance and progression of specific subtypes of DLBCL are necessary in order to develop novel therapeutics against them. Increased NFkB activity and p53 deregulation