Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher N Woods"'
Autor:
Eugene Serebryany, Sourav Chowdhury, Christopher N Woods, David C Thorn, Nicki E Watson, Arthur A McClelland, Rachel E Klevit, Eugene I Shakhnovich
Publikováno v:
eLife, Vol 11 (2022)
Cataract is one of the most prevalent protein aggregation disorders and still the most common cause of vision loss worldwide. The metabolically quiescent core region of the human lens lacks cellular or protein turnover; it has therefore evolved remar
Externí odkaz:
https://doaj.org/article/2ce524a68f244c33ab72c1d61438b0f5
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Small heat-shock proteins (sHSPs) are a widely expressed family of ATP-independent molecular chaperones that are among the first responders to cellular stress. Mechanisms by which sHSPs delay aggregation of client proteins remain undefined. sHSPs hav
Autor:
Christopher N Woods, Lindsey D Ulmer, Maria K Janowska, Natalie L Stone, Ellie I James, Miklos Guttman, Matthew F Bush, Rachel E Klevit
Small heat shock proteins (sHSPs) are chaperones whose importance in protein homeostasis is exemplified by dozens of missense mutations associated with tissue-specific disease states. Despite decades of studies, the structure, dynamics, and mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f957b193fd5e65cd4d4016255409c6
https://doi.org/10.1101/2022.05.30.493970
https://doi.org/10.1101/2022.05.30.493970
Autor:
Eugene Serebryany, Sourav Chowdhury, Christopher N Woods, David C Thorn, Nicki E Watson, Arthur A McClelland, Rachel E Klevit, Eugene I Shakhnovich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::569b275551a93cde988e7065c5df22ff
https://doi.org/10.7554/elife.76923.sa2
https://doi.org/10.7554/elife.76923.sa2
Autor:
Eugene Serebryany, Sourav Chowdhury, Christopher N. Woods, David C. Thorn, Nicki E. Watson, Arthur McClelland, Rachel E. Klevit, Eugene I. Shakhnovich
Cataract is one of the most prevalent protein aggregation disorders and still the most common cause of vision loss worldwide. The metabolically quiescent core region of the human lens lacks cellular or protein turnover; it has therefore evolved remar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3719b970441bad018a93dea30284472
https://doi.org/10.1101/2020.12.16.423154
https://doi.org/10.1101/2020.12.16.423154
Publikováno v:
Cold Spring Harb Perspect Biol
Small heat shock proteins (sHSPs) are ATP-independent chaperones that delay formation of harmful protein aggregates. sHSPs' role in protein homeostasis has been appreciated for decades, but their mechanisms of action remain poorly understood. This ga
Autor:
Todd Weaver, Walter R. P. Novak, Megan R. Wimmer, Daniel Grilley, Kyle J. Adamczak, Christopher N. Woods, Evan M. Glasgow
Publikováno v:
Protein Science. 28:1913-1913
Protein secretion is a major contributor to Gram-negative bacterial virulence. Type Vb or two-partner secretion (TPS) pathways utilize a membrane bound β-barrel B component (TpsB) to translocate large and predominantly virulent exoproteins (TpsA) th
Publikováno v:
The FASEB Journal. 29