Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher N Goulbourne"'
Autor:
Thomas Q. de Aguiar Vallim, Elinor Lee, David J. Merriott, Christopher N. Goulbourne, Joan Cheng, Angela Cheng, Ayelet Gonen, Ryan M. Allen, Elisa N.D. Palladino, David A. Ford, Tisha Wang, Ángel Baldán, Elizabeth J. Tarling
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 941-954 (2017)
Idiopathic pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of surfactant. Surfactant synthesis and secretion are restricted to epithelial type 2 (T2) pneumocytes (also called T2 cells). Clearance of surfactan
Externí odkaz:
https://doaj.org/article/195fb965f0f14ca3bfe255e6d4389a1f
Autor:
Rita De Gasperi, Jiangping Pan, Christopher Cardozo, Christopher N Goulbourne, Chenglin Mo, Daniella Azulai, William A. Bauman, Fred C. Ko, Bin Zhang, Lei Guo, Ashleigh M. Raczkowski, Xin-Hua Liu, Marco Brotto, Wei Zhao, Yating Du, Zachary A. Graham, Zhiying Wang, Lauren Harlow
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 454-466 (2022)
BackgroundThe role of Numb, a protein that is important for cell fate and development was investigated in adult skeletal muscle in mice using a conditional, inducible knockout (cKO) model.MethodsNumb expression was evaluated by Western blot. Numb loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5678ea7c97a0f5dd82a99c4ac72a41a6
https://doaj.org/article/e3de719d0af0427d8b54e419b4474d11
https://doaj.org/article/e3de719d0af0427d8b54e419b4474d11
Autor:
Haoquan Zhao, Rudolph Leibel, Christopher N Goulbourne, Jose Oberholzer, Jaeyop Lee, Yufeng Shen, Yuan Xing, Damian J. Williams, Robin Goland, Jesper Gromada, Henry M. Colecraft, Charles A. LeDuc, Jacqueline Niu, Xiajuan Chen, Wendy K. Chung, Dieter Egli, Yong Wang, Bryan J. González
Mutations in HNF1A cause Maturity Onset Diabetes of the Young type 3 (MODY3), the most prevalent form of monogenic diabetes. Using stem cell-derived pancreatic endocrine cells from human embryonic stem cells (hESCs) with induced hypomorphic mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565b155cffa400ec721706fdf1ec43eb
https://doi.org/10.21203/rs.3.rs-509878/v1
https://doi.org/10.21203/rs.3.rs-509878/v1
Autor:
Robin Goland, Bryan J. González, Jesper Gromada, Yufeng Shen, Christopher N Goulbourne, Jacqueline Niu, Yuan Xing, Wendy K. Chung, Henry M. Colecraft, Dieter Egli, Xiaojuan Chen, Yong Wang, Jose Oberholzer, Charles A. LeDuc, Rudolph L. Leibel, Haoquan Zhao, Damian J. Williams, Jaeyop Lee
Mutations in HNF1A cause Maturity Onset Diabetes of the Young type 3 (MODY3), the most prevalent form of monogenic diabetes. We generated stem cell-derived pancreatic endocrine cells from human embryonic stem cells (hESCs) with induced hypomorphic mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5393408f63dc4356887e7df9900f2a9
https://doi.org/10.1101/2021.01.26.428260
https://doi.org/10.1101/2021.01.26.428260
Autor:
Thomas Q de Aguiar Vallim, Elinor Lee, David J Merriott, Christopher N Goulbourne, Joan Cheng, Angela Cheng, Ayelet Gonen, Elisa N Palldino, Katayun Barmak, David A Ford, Tisha Wang, Angel Baldan, Elizabeth J Tarling
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Inflammation is a hallmark characteristic of many diseases, including atherosclerosis and respiratory distress, and it is also a stereotypical response of the innate immune system to pathogens. Given the central role both inflammation and lipid homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620251a949b69b77efacf057c138b963
https://doi.org/10.1161/atvb.37.suppl_1.172
https://doi.org/10.1161/atvb.37.suppl_1.172
Autor:
Thomas Q de Aguiar Vallim, Christopher N Goulbourne, Joan Cheng, Tieyan Han, Joy Frank, David A Ford, Angel Baldan, Elizabeth Tarling
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Pulmonary alveolar proteinosis (PAP) is a rare disease caused by the accumulation of surfactant proteins and lipids in the pulmonary alveoli resulting in respiratory distress. For almost all reported cases the underlying cause is unknown. Synthesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5b06e60a355c67f07d9da7160ec0b5b
https://doi.org/10.1161/atvb.35.suppl_1.328
https://doi.org/10.1161/atvb.35.suppl_1.328