Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Christopher Monson"'
1
Akademický článek
A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation
Autor: Jaime Chu, Alexander Mir, Ningguo Gao, Sabrina Rosa, Christopher Monson, Vandana Sharma, Richard Steet, Hudson H. Freeze, Mark A. Lehrman, Kirsten C. Sadler
Publikováno v: Disease Models & Mechanisms, Vol 6, Iss 1, Pp 95-105 (2013)
SUMMARY Individuals with congenital disorders of glycosylation (CDG) have recessive mutations in genes required for protein N-glycosylation, resulting in multi-systemic disease. Despite the well-characterized biochemical consequences in these individ
Externí odkaz: https://doaj.org/article/294b374090034630ba6dfa33c2843e27
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2
Akademický článek
Semiotics of making: beginnings of a theoretical frame
Autor: Christopher Monson
Publikováno v: Enquiry: The ARCC Journal of Architectural Research, Vol 5, Iss 1 (2008)
The contemporary problem of semiotics in architecture is an inherited struggle, not a chosen one. We consider the question of architectural communication because we inevitably recognize its centrality to the problem ofarchitecture itself. While the t
Externí odkaz: https://doaj.org/article/a4d5d124c0ad48898d3cca981003e1ae
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4
In vitro exposure of vitellogenic rainbow trout ovarian follicles to endocrine disrupting chemicals can alter basal estradiol-17β production and responsiveness to a gonadotropin challenge
Autor: Christopher Monson, Graham Young, Irvin R. Schultz
Publikováno v: Aquatic toxicology (Amsterdam, Netherlands). 217
Endogenous estrogens play major roles in many aspects of female reproductive development in fish. In order to develop a relatively high-throughput assay to determine the potential impact on reproductive development, vitellogenic rainbow trout ovarian
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a4b770414afcbe00027d8b7fcb0884
https://pubmed.ncbi.nlm.nih.gov/31704580
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5
A teleost androgen promotes development of primary ovarian follicles in coho salmon and rapidly alters the ovarian transcriptome
Autor: Christopher Monson, Kristy L. Forsgren, Giles Goetz, Penny Swanson, Louisa B. Harding, Graham Young
Publikováno v: Biology of reproduction. 97(5)
Recent studies using several teleost models have revealed that androgens increase the size of previtellogenic (primary and/or early secondary) ovarian follicles. To explore our hypothesis that androgens drive the development of primary follicles into
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5101c65e7e00af9d3eaaa10ec03934
https://pubmed.ncbi.nlm.nih.gov/29045593
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6
A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation
Autor: Richard Steet, Sabrina Rosa, Ningguo Gao, Jaime Chu, Mark A. Lehrman, Vandana Sharma, Kirsten C. Sadler, Christopher Monson, Alexander Mir, Hudson H. Freeze
Publikováno v: Disease Models & Mechanisms, Vol 6, Iss 1, Pp 95-105 (2013)
Disease Models & Mechanisms
Summary Individuals with congenital disorders of glycosylation (CDG) have recessive mutations in genes required for protein N-glycosylation, resulting in multi-systemic disease. Despite the well-characterized biochemical consequences in these individ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f519f6606cfe0a8858b662f0249518d
http://dmm.biologists.org/content/6/1/95
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7
Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells
Autor: Christopher Monson, Valerie Gouon-Evans, Scott L. Friedman, Nobuyuki Matsumoto, Chuan Gao, Xiao Zhao, Kirsten C. Sadler
Publikováno v: Developmental Biology. 344:79-93
Krüppel-like factor 6 (Klf6; copeb in zebrafish) is a zinc-finger transcription factor and tumor suppressor gene. Klf6(-)(/)(-) mice have defects in hematopoiesis and angiogenesis and do not form a liver. However, the vascular abnormalities in Klf6(
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38258b082c4db18e1c7e15315156a892
https://doi.org/10.1016/j.ydbio.2010.04.018
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8
The Role of Insulin Receptor Signaling in Zebrafish Embryogenesis
Autor: Chuan Gao, Kirsten C. Sadler, Shoshana Yakar, Yuka Toyoshima, Yingjie Wu, Cunming Duan, Derek LeRoith, Christopher Monson
Publikováno v: Endocrinology. 149:5996-6005
Insulin receptor (IR) signaling is considered to be important in growth and development in addition to its major role in metabolic homeostasis. The metabolic role of insulin in carbohydrate and lipid metabolism is extensively studied. In contrast, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7f945be7010cb9461087f72abd8b11
https://doi.org/10.1210/en.2008-0329
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9
Practical discourse: Learning and the ethical construction of environmental design practice
Autor: Christopher Monson
Publikováno v: Ethics, Place & Environment. 8:181-200
Through established modern theories of design thinking, the internalization of environmental design through studio education is fundamentally a construct of ego-centrism. This fact subsequently inhibits an intersubjective and discursive professional
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85f8df5c3a41b3aa7ee67119a562e6c3
https://doi.org/10.1080/13668790500237070
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