Výsledky vyhledávání - "Christopher Maurice Preston"

Investigation of herpes simplex virus type 1 (HSV-1) gene expression and DNA synthesis during the establishment of latent infection by an HSV-1 mutant, in1814, that does not replicate in mouse trigeminal ganglia

Autor: Nigel W. Fraser, Christopher Maurice Preston, Israel Steiner, Jordan G. Spivack, Chris I. Ace, Tibor Valyi-Nagy, S L Deshmane

Publikováno v: Journal of General Virology. 72:641-649

In previous studies, the herpes simplex virus type 1 (HSV-1) mutant, in1814, which lacks the trans-inducing function of Vmw65, did not replicate in the trigeminal ganglia of mice following corneal inoculation but did establish a reactivatable latent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db22d5cf77f434e6dd6361d5d746890
https://doi.org/10.1099/0022-1317-72-3-641

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A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia

Autor: Israel Steiner, Christopher Maurice Preston, C I Ace, S L Deshmane, J G Spivack, Nigel W. Fraser

Vmw65, a herpes simplex virus type 1 (HSV-1) tegument protein, in association with cellular proteins, transactivates viral immediate early genes. In order to examine the role of Vmw65 during acute and latent infection in vivo, a mutant virus (in1814)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15b5def7eaf959b6f827360c2c2b874
https://europepmc.org/articles/PMC249299/

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