Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Christopher M.C. Ng"'
Autor:
Toni L. Richards, Bruce H. Mandt, Richard M. Allen, Diana L. Simmons, Christopher M.C. Ng, Nancy R. Zahniser, Dorothy J. Yamamoto
Publikováno v:
Neuropharmacology. 75:347-355
Behavioral responsiveness to initial cocaine use varies among individuals and may contribute to differential vulnerability to cocaine addiction. Rats also exhibit individual differences in cocaine’s effects and can be classified as low or high coca
Autor:
Bruce H. Mandt, Toni L. Richards, Gaynor A. Larson, Jacki M. Rorabaugh, Christopher M.C. Ng, Nancy R. Zahniser, Dorothy J. Yamamoto, Kelsey Barcomb, Richard M. Allen, Anna M. Nelson
Publikováno v:
Neuroscience & Biobehavioral Reviews. 37:1738-1753
Individual differences are a hallmark of drug addiction. Here, we describe a rat model based on differential initial responsiveness to low dose cocaine. Despite similar brain cocaine levels, individual outbred Sprague-Dawley rats exhibit markedly dif