Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christopher M. Yan"'
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 634 (2019)
We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12analog-sensitive HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in huma
Externí odkaz:
https://doaj.org/article/4a2a99b3d3f54660a4a959687788d89f
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1849:1179-1187
The RNA Polymerase II C-terminal domain (CTD) kinase CDK12 has been implicated as a tumor suppressor and regulator of DNA damage response genes. Although much has been learned about CDK12 and its activity, due to the lack of a specific inhibitor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf29e6e7a5c307a189d06b831694a47
https://doi.org/10.1016/j.bbagrm.2015.07.010
https://doi.org/10.1016/j.bbagrm.2015.07.010
Publikováno v:
Biomolecules
Volume 9
Issue 10
Biomolecules, Vol 9, Iss 10, p 634 (2019)
Volume 9
Issue 10
Biomolecules, Vol 9, Iss 10, p 634 (2019)
We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12analog-sensitive HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38263d6dbb32480ff3295586d4f5cdf
https://doi.org/10.3390/biom9100634
https://doi.org/10.3390/biom9100634
Publikováno v:
Developmental Biology. 380:111-124
Polycomb group (PcG) proteins are best known for their role in maintaining stable, mitotically heritable silencing of the homeotic (HOX) genes during development. In addition to loss of homeotic gene silencing, some PcG mutants also have small imagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b689cee3ee1b53b6a7302e53bf7d801d
https://doi.org/10.1016/j.ydbio.2013.03.011
https://doi.org/10.1016/j.ydbio.2013.03.011
Autor:
William Kim, Alessio Bocedi, Pavel A. Nikitin, Jason P. Tourigny, Martin J. Allday, Katherine Hu, Christopher M. Yan, Jing Guo, Elena Rusyn, Sandeep S. Dave, Amee Patel, Micah A. Luftig, Robert E. White, Eleonora Forte, David M. Tainter
Publikováno v:
Cell host & microbe
Evaluation of: Nikitin PA, Yan CM, Forte E et al.: An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell. Host Microbe 8(6), 510-522 (2010). Viruses have evolved elega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caa89e738b6f37d8331f379414ba493
Autor:
Gary H. Karpen, David Acevedo, Christopher M Yan, Alexander Y Konev, Cameron Kennedy, Sanjay Tickoo, Arlene Lim, Elaina Ward
Publikováno v:
Genetics. 165(4)
Heterochromatin is a major component of higher eukaryotic genomes, but progress in understanding the molecular structure and composition of heterochromatin has lagged behind the production of relatively complete euchromatic genome sequences. The intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166cd234b287608b8da528064a2115c0
https://pubmed.ncbi.nlm.nih.gov/14704184
https://pubmed.ncbi.nlm.nih.gov/14704184
Publikováno v:
Genetics. 161(1)
Approximately one-third of the human and Drosophila melanogaster genomes are heterochromatic, yet we know very little about the structure and function of this enigmatic component of eukaryotic genomes. To facilitate molecular and cytological analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9768f3bfa1e65fc6a20341378641cfa
https://pubmed.ncbi.nlm.nih.gov/12019236
https://pubmed.ncbi.nlm.nih.gov/12019236
Autor:
Christopher M. Yan, Brankica Mravinac, Kristen S. Kopf, Lori L. Sullivan, Beth A. Sullivan, Christine J. Farr, Mary G. Schueler, Jason Reeves
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6602 (2009)
PLoS ONE
PLoS ONE
Human centromeres are multi-megabase regions of highly ordered arrays of alpha satellite DNA that are separated from chromosome arms by unordered alpha satellite monomers and other repetitive elements. Complexities in assembling such large repetitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af81bb1ca3a98a87747cd381df065cf
https://doi.org/10.1371/journal.pone.0006602
https://doi.org/10.1371/journal.pone.0006602
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87299 (2014)
B-cell activation and proliferation can be induced by a variety of extracellular stimuli. The fate of an activated B cell following mitogen stimulation can be dictated by the strength or duration of the signal, the expression of downstream signaling
Externí odkaz:
https://doaj.org/article/ccc97e00edf3476d84f611b0175c2a3e
Autor:
Brankica Mravinac, Lori L Sullivan, Jason W Reeves, Christopher M Yan, Kristen S Kopf, Christine J Farr, Mary G Schueler, Beth A Sullivan
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6602 (2009)
Human centromeres are multi-megabase regions of highly ordered arrays of alpha satellite DNA that are separated from chromosome arms by unordered alpha satellite monomers and other repetitive elements. Complexities in assembling such large repetitive
Externí odkaz:
https://doaj.org/article/ee4563d4506e4999bfbc6e80983bf9c6