Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Christopher M. Walthers"'
Publikováno v:
Biomarker Insights, Vol 2015, Iss Suppl. 1, Pp 11-29 (2015)
Externí odkaz:
https://doaj.org/article/e48bad1ae0f5476199e417e25afcc249
Autor:
Yvonne Y. Chen, Antoni Ribas, John M. Timmerman, Gary J. Schiller, Caspian Oliai, Patricia A. Young, Sven de Vos, Monica Mead, Karla Nawaly, Jonathan Said, Martin S. Allen-Auerbach, Melanie Ayala Ceja, Amr Almaktari, Stanley B. Gosliner, Beata Berent-Maoz, Thomas Schweppe, Mobina Khericha, Caitlin Harris, Mobina Roshandell, Jia Ming Chen, Jacqueline Trent, Jacob Naparstek, Sanaz N. Ghafouri, Brenda Ji, Christopher M. Walthers, Sarah M. Larson
CART19/20 cell product characteristics. (A) % CD4+ among total T cells and CAR-expressing T cells. (B) Comparison of T-cell subtype frequency among CD4+ vs. CD8+ T cells in cryopreserved CART19/20 cell products. Te/exh: effector/exhausted T cells, CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e23adcca8d5d92e2da936e75c073574
https://doi.org/10.1158/2159-8290.22542543
https://doi.org/10.1158/2159-8290.22542543
Autor:
Yvonne Y. Chen, Antoni Ribas, John M. Timmerman, Gary J. Schiller, Caspian Oliai, Patricia A. Young, Sven de Vos, Monica Mead, Karla Nawaly, Jonathan Said, Martin S. Allen-Auerbach, Melanie Ayala Ceja, Amr Almaktari, Stanley B. Gosliner, Beata Berent-Maoz, Thomas Schweppe, Mobina Khericha, Caitlin Harris, Mobina Roshandell, Jia Ming Chen, Jacqueline Trent, Jacob Naparstek, Sanaz N. Ghafouri, Brenda Ji, Christopher M. Walthers, Sarah M. Larson
To address antigen escape and loss of T-cell functionality, we report a phase I clinical trial (NCT04007029) evaluating autologous naive and memory T (TN/MEM) cells engineered to express a bispecific anti-CD19/CD20 chimeric antigen receptor (CAR; CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050a671732fa83e533f6d56dd43cca46
https://doi.org/10.1158/2159-8290.c.6549963
https://doi.org/10.1158/2159-8290.c.6549963
Autor:
Yvonne Y. Chen, Antoni Ribas, John M. Timmerman, Gary J. Schiller, Caspian Oliai, Patricia A. Young, Sven de Vos, Monica Mead, Karla Nawaly, Jonathan Said, Martin S. Allen-Auerbach, Melanie Ayala Ceja, Amr Almaktari, Stanley B. Gosliner, Beata Berent-Maoz, Thomas Schweppe, Mobina Khericha, Caitlin Harris, Mobina Roshandell, Jia Ming Chen, Jacqueline Trent, Jacob Naparstek, Sanaz N. Ghafouri, Brenda Ji, Christopher M. Walthers, Sarah M. Larson
Representativeness of study participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5e747491d7940bb0d582091c2fa708
https://doi.org/10.1158/2159-8290.22542522
https://doi.org/10.1158/2159-8290.22542522
Autor:
Stephanie K. Seidlits, David A. Nathanson, Lisa Ta, Christopher M. Walthers, Jesse Liang, Songping Sun, Arshia Ehsanipour, Alireza Sohrabi, Rongyu Zhang, Weikun Xiao
Supplementary Methods describing additional information for procedures in manuscript, including hydrogel fabrication, hydrogel sample cryopreservation, lentivirus preparation, mechanical characterization, diffusion, western blotting, and statistics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3469fd8001cbce130a8bdd9f46a49a
https://doi.org/10.1158/0008-5472.22410936
https://doi.org/10.1158/0008-5472.22410936
Autor:
Stephanie K. Seidlits, David A. Nathanson, Lisa Ta, Christopher M. Walthers, Jesse Liang, Songping Sun, Arshia Ehsanipour, Alireza Sohrabi, Rongyu Zhang, Weikun Xiao
Glioblastoma (GBM) tumors exhibit potentially actionable genetic alterations against which targeted therapies have been effective in treatment of other cancers. However, these therapies have largely failed in GBM patients. A notable example is kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400009f65bed01cea05a1dd712c4c89b
https://doi.org/10.1158/0008-5472.c.6508110
https://doi.org/10.1158/0008-5472.c.6508110
Autor:
Stephanie K. Seidlits, David A. Nathanson, Lisa Ta, Christopher M. Walthers, Jesse Liang, Songping Sun, Arshia Ehsanipour, Alireza Sohrabi, Rongyu Zhang, Weikun Xiao
Supplementary figures S1-S12 providing necessary data on additional animal xenograft experiments, essential information characterizing cell lines used in manuscript, and controls for immunostaining and western blots. This supplementary file also prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44531253165cc6f7722ef18548067d9f
https://doi.org/10.1158/0008-5472.22410939
https://doi.org/10.1158/0008-5472.22410939
Autor:
Qianqian Wang, Ke Wang, R Sergio Solorzano-Vargas, Po-Yu Lin, Christopher M Walthers, Anne-Laure Thomas, Martín G Martín, James C Y Dunn
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0195315 (2018)
Although critical for studies of gut motility and intestinal regeneration, the in vitro culture of intestinal muscularis with peristaltic function remains a significant challenge. Periodic contractions of intestinal muscularis result from the coordin
Externí odkaz:
https://doaj.org/article/3035547c8dcc4a8d9a7fe06dbcc03d3d
Autor:
Sarah M. Larson, Christopher M. Walthers, Brenda Ji, Sanaz N. Ghafouri, Jacob Naparstek, Jacqueline Trent, Jia Ming Chen, Mobina Roshandell, Caitlin Harris, Mobina Khericha, Thomas Schweppe, Beata Berent-Maoz, Stanley B. Gosliner, Amr Almaktari, Melanie Ayala Ceja, Martin S. Allen-Auerbach, Jonathan Said, Karla Nawaly, Monica Mead, Sven de Vos, Patricia A. Young, Caspian Oliai, Gary J. Schiller, John M. Timmerman, Antoni Ribas, Yvonne Y. Chen
Publikováno v:
Cancer discovery.
To address antigen escape and loss of T-cell functionality, we report a phase I clinical trial (NCT04007029) evaluating autologous naive and memory T (TN/MEM) cells engineered to express a bispecific anti-CD19/CD20 chimeric antigen receptor (CAR; CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167a18da8ab9ceb6fa875422b5dc430d
https://pubmed.ncbi.nlm.nih.gov/36416874
https://pubmed.ncbi.nlm.nih.gov/36416874
Autor:
Brenda Y. Ji, John M. Timmerman, Monica Mead, Jia Ming Chen, Sanaz Ghafouri, Jacqueline Trent, Christopher M. Walthers, Jacob Naparstek, Mobina Roshandell, Yvonne Y. Chen, Sarah Larson
Publikováno v:
Blood. 136:19-20
Background: Single-input anti-CD19 CAR T-cells have demonstrated clinical efficacy for relapsed or refractory (R/R) non-Hodgkin B-cell lymphoma (NHL) and chronic lymphocytic leukemia (CLL). Despite excellent response rates, over 50% of CD19 CAR T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8614b544cd2a61dbdd9f69f12f58761
https://doi.org/10.1182/blood-2020-137630
https://doi.org/10.1182/blood-2020-137630