Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christopher M. Tracy"'
Autor:
Stavros G. Drakos, Rachit Badolia, Aman Makaju, Christos P. Kyriakopoulos, Omar Wever-Pinzon, Christopher M. Tracy, Anna Bakhtina, Ryan Bia, Timothy Parnell, Iosif Taleb, Dinesh K.A. Ramadurai, Sutip Navankasattusas, Elizabeth Dranow, Thomas C. Hanff, Eleni Tseliou, Thirupura S. Shankar, Joseph Visker, Rana Hamouche, Elizabeth L. Stauder, William T. Caine, Rami Alharethi, Craig H. Selzman, Sarah Franklin
Publikováno v:
Circulation.
Background: Extensive evidence from single-center studies indicates that a subset of patients with chronic advanced heart failure (HF) undergoing left ventricular assist device (LVAD) support show significantly improved heart function and reverse str
Autor:
Maureen Walsh, Sarah Franklin, Katsuhiko Funai, Garcia-Llano June, Marta W. Szulik, Ryan Bia, Anil Laxman, Dipayan Chaudhuri, Mickey R. Miller, Emilee Horiuchi, Christopher M. Tracy, Sihem Boudina, Steven Valdez, Sean A. O’Very, Li Wang, Kathryn Davis, Stavros G. Drakos
Publikováno v:
Circulation Research. 129
SMYD1a, a myosin-specific histone lysine methyltransferase, plays a major role in regulating disease-induced remodeling in the adult heart. Previously, we demonstrated that the inducible loss of this chromatin-bound enzyme is sufficient to induce car
Autor:
Christopher M Tracy, Alexander V Kolesnikov, Devon R Blake, Ching-Kang Chen, Wolfgang Baehr, Vladimir J Kefalov, Barry M Willardson
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117129 (2015)
G protein β subunits (Gβ) play essential roles in phototransduction as part of G protein βγ (Gβγ) and regulator of G protein signaling 9 (RGS9)-Gβ5 heterodimers. Both are obligate dimers that rely on the cytosolic chaperone CCT and its co-chap
Externí odkaz:
https://doaj.org/article/41dd7572ce18406d9175fa0dc4ac2c64
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Inorganic Chemistry. 58:43-46
Classical maleimide Michael addition chemistry in conjunction with copper-free click chemistry was investigated as a synthetic strategy to attach cytotoxic platinum–acridine hybrid agents to carrier proteins. The structural integrity and selectivit
Autor:
Sarah Franklin, Marta W. Szulik, Kristi L. Russell, Mickey R. Miller, Junco S. Warren, June Garcia, Li Wang, Christopher M. Tracy, Aman Makaju
Publikováno v:
Current Opinion in Physiology. 1:140-152
Protein methylation plays a pivotal role in the regulation of various cellular processes including chromatin remodeling and gene expression. SET and MYND domain-containing proteins (Smyd) are a special class of lysine methyltransferases whose catalyt
Publikováno v:
Chembiochem : a European journal of chemical biology. 20(3)
Histones, the fundamental building blocks of nucleosomes, undergo post-translational modifications and play a major role in the regulation of transcriptional processes. Although the significance of these modifications, including methylation, is widel
Autor:
Aman Makaju, Craig H. Selzman, Sutip Navankasattusas, Stavros G. Drakos, Lauren McCreath, Sarah Franklin, Christopher M. Tracy, Nikolaos A. Diakos
Publikováno v:
Circulation Research. 123
The classical view of the human heart characterizes it as an organ with limited ability to recover and restore itself. Consequently, left ventricular assist devices (LVAD), which provide mechanical circulatory support and profound ventricular unloadi
Autor:
Oliver Fiehn, Yong Hwan Han, Li Wang, Bucky K. Lozier, Alexey V. Zaitsev, Keiko M. Cawley, Haley O. Tucker, Dane W. Barton, Shin Ichi Oka, Tatiana Yuzyuk, Marta W. Szulik, Sihem Boudina, Aman Makaju, James E. Cox, Sarah Franklin, Anil Kumar, Christopher M. Tracy, June García Llana, Junco S. Warren, Amira D. Sabry, Mickey R. Miller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 33
Smyd1, a muscle-specific histone methyltransferase, has established roles in skeletal and cardiac muscle development, but its role in the adult heart remains poorly understood. Our prior work demonstrated that cardiac-specific deletion of Smyd1 in ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfe9f171a6775148864dc3039a20f75
https://escholarship.org/uc/item/40v3856w
https://escholarship.org/uc/item/40v3856w
Autor:
Jessica Meznarich, Jason Singer, Sunil Sharma, Matt Velinder, Christopher M. Tracy, Diana Bareyan, Michael E. Engel, Sarah Franklin, David McClellan, Helena Lucente, James M Fulcher
Publikováno v:
Biochem J
Proper hematopoietic cell fate decisions require co-ordinated functions of transcription factors, their associated co-regulators, and histone-modifying enzymes. Growth factor independence 1 (GFI1) is a zinc finger transcriptional repressor and master