Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Christopher M. Sanchez"'
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Prostanoid EP1 receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB
Autor: Xiao Bo Chen, John W. Regan, Chih-Ling Chou, D.F. Woodward, Ruyue Ji, Christopher M. Sanchez
Publikováno v: British Journal of Pharmacology. 166:1033-1046
BACKGROUND AND PURPOSE Prostaglandin E2 (PGE2) stimulation of the G protein-coupled prostanoid EP1 receptor was found to up-regulate the expression of Nur-related factor 1 (Nurr1) (NR4A2), a transcription factor in the NR4A subfamily of nuclear recep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f68e045d1a7e36ec35d767b045fb56d9
https://doi.org/10.1111/j.1476-5381.2011.01817.x
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6
Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1α in HCA-7 human colon cancer cells
Autor: Kenji Yoshida, Sho Otake, John W. Regan, Naofumi Seira, Hiromichi Fujino, Christopher M. Sanchez, Toshihiko Murayama
Publikováno v: Pharmacology Research & Perspectives
Increases in prostaglandin E2 (PGE2) and cyclooxygenase-2 (COX-2) levels are features of colon cancer. Among the different E-type prostanoid receptor subtypes, EP4 receptors are considered to play a crucial role in carcinogenesis by, for example, ind
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6facbce4ce559fddc27d74306e828
https://pubmed.ncbi.nlm.nih.gov/25692008
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