Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Christopher M. Read"'
Publikováno v:
European Biophysics Journal
Crane-Robinson, C, Read, C & Dragan, A 2018, ' Hydration differences between the major and minor grooves of DNA revealed from heat capacity measurements ', European Biophysics Journal . https://doi.org/10.1007/s00249-018-1340-0
Crane-Robinson, C, Read, C & Dragan, A 2018, ' Hydration differences between the major and minor grooves of DNA revealed from heat capacity measurements ', European Biophysics Journal . https://doi.org/10.1007/s00249-018-1340-0
The nature of water on the surface of a macromolecule is reflected in the temperature dependence of the heat effect, i.e., the heat capacity change, ΔCp, that accompanies its removal on forming a complex. The relationship between ΔCp and the nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc49818134fb8384723fd9b90ee5a05
https://doi.org/10.1007/s00249-018-1340-0
https://doi.org/10.1007/s00249-018-1340-0
Autor:
Jana Sopkova-de Oliveira Santos, Christopher M. Read, Elke Haensele, Lee Banting, Timothy Clark, Alban Lepailleur, David C. Whitley, Carla Delépée, Ronan Bureau, Marija Miljak, Nawel Mele, Jonathan W. Essex
Publikováno v:
Haensele, E, Mele, N, Miljak, M, Read, C M, Whitley, D C, Banting, L, Delepee, C, Sopková-de Oliveira Santos, J, Lepailleur, A, Bureau, R, Essex, J W & Clark, T 2017, ' Conformation and dynamics of human urotensin II and urotensin related peptide in aqueous solution ', Journal of Chemical Information and Modelling, vol. 57, no. 2, pp. 298-310 . https://doi.org/10.1021/acs.jcim.6b00706
Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, American Chemical Society, 2017, 57 (2), pp.298-310. ⟨10.1021/acs.jcim.6b00706⟩
Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, American Chemical Society, 2017, 57 (2), pp.298-310. ⟨10.1021/acs.jcim.6b00706⟩
International audience; Conformation and dynamics of the vasoconstrictive peptides human urotensin II (UII) and urotensin related peptide (URP) have been investigated by both unrestrained and enhanced-sampling molecular-dynamics (MD) simulations and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4665fc3e7ab15d62a6e4813ee149851f
https://doi.org/10.1021/acs.jcim.6b00706
https://doi.org/10.1021/acs.jcim.6b00706
Autor:
Noureldin Saleh, Lee Banting, Elke Haensele, Christopher M. Read, David C. Whitley, Timothy Clark
Publikováno v:
Haensele, E, Saleh, N, Read, C M, Banting, L, Whitley, D C & Clark, T 2016, ' Can simulations and modeling decipher NMR data for conformational equilibria? Arginine–vasopressin ', Journal of Chemical Information and Modelling, vol. 56, no. 9, pp. 1798-1807 . https://doi.org/10.1021/acs.jcim.6b00344
Arginine vasopressin (AVP) has been suggested by molecular-dynamics (MD) simulations to exist as a mixture of conformations in solution. The 1H and 13C NMR chemical shifts of AVP in solution have been calculated for this conformational ensemble of ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b59275f3ed909ad23775a8c323d1cb
https://doi.org/10.1021/acs.jcim.6b00344
https://doi.org/10.1021/acs.jcim.6b00344
Publikováno v:
Wu, C, Read, C, Mcgeehan, J & Crane-robinson, C 2016, ' The construction of customised nucleosomal arrays ', Analytical Biochemistry, vol. 496, pp. 71-75 . https://doi.org/10.1016/j.ab.2015.11.018
A simple, efficient, and reliable method is demonstrated for cloning long tandem arrays of the 601 nucleosomal positioning sequence. In addition, it is shown that such long arrays can be ligated together in vitro with high efficiency. By combining th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02810ef312432e886717885646476893
https://doi.org/10.1016/j.ab.2015.11.018
https://doi.org/10.1016/j.ab.2015.11.018
Publikováno v:
European Biophysics Journal
Dragan, A I, Read, C & Crane-Robinson, C 2017, ' Enthalpy-entropy compensation : the role of solvation ', European Biophysics Journal, vol. 46, no. 4, pp. 301-308 . https://doi.org/10.1007/s00249-016-1182-6
Dragan, A I, Read, C & Crane-Robinson, C 2017, ' Enthalpy-entropy compensation : the role of solvation ', European Biophysics Journal, vol. 46, no. 4, pp. 301-308 . https://doi.org/10.1007/s00249-016-1182-6
Structural modifications to interacting systems frequently lead to changes in both the enthalpy (heat) and entropy of the process that compensate each other, so that the Gibbs free energy is little changed: a major barrier to the development of lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e80074399a6d8543ff5179a48fd4e0
https://pubmed.ncbi.nlm.nih.gov/27796417
https://pubmed.ncbi.nlm.nih.gov/27796417
Autor:
Christopher M. Read, Laurence H. Arnold, Gregg B. Fields, Stephen H. Prior, Andrew R. Pickford, Louise E. Butt
Publikováno v:
Journal of Biological Chemistry. 286:45073-45082
Matrix metalloproteinase-1 (MMP-1) is an instigator of collagenolysis, the catabolism of triple helical collagen. Previous studies have implicated its hemopexin (HPX) domain in binding and possibly destabilizing the collagen substrate in preparation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b635d844e2b6ba9b08c195caceae8e0
https://doi.org/10.1074/jbc.m111.285213
https://doi.org/10.1074/jbc.m111.285213
Autor:
Christopher M. Read, Andrew F. Bent, Richard Bazin, Chris Phillips, Lee R. Roberts, Stephen L. Irving, Andrew D. Scott, Andrew R. Pickford, Markus Schade, Nichola L. Davies, Andrew Pannifer, Robert Moore, David G. Brown, Stephen H. Prior, Bin Xu
Publikováno v:
Journal of the American Chemical Society. 133:9696-9699
Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach to small molecules for the modulation of receptor signaling and subsequent gene expression. Here we describe the design of a series of novel stapled pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efdcba56a3c70498be1c19224dec569
https://doi.org/10.1021/ja202946k
https://doi.org/10.1021/ja202946k
Autor:
Christopher M. Read, Colyn Crane-Robinson, Peter L. Privalov, Ekaterina I. Milgotina, Anatoly I. Dragan, Mair E. A. Churchill, Elena N. Makeyeva
Publikováno v:
Journal of Molecular Biology. 343:371-393
To clarify the physical basis of DNA binding specificity, the thermodynamic properties and DNA binding and bending abilities of the DNA binding domains (DBDs) of sequence-specific (SS) and non-sequence-specific (NSS) HMG box proteins were studied wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e38b3b64619a8112cf7c405f12409d
https://doi.org/10.1016/j.jmb.2004.08.035
https://doi.org/10.1016/j.jmb.2004.08.035
Autor:
Maria R. Conte, Dmitri I. Svergun, Peter V. Konarev, Andrea Szendröi, Tom P. Monie, Stephen Matthews, Natalia Davydova, Peter D. Cary, Stephen Curry, Peter Simpson, Jonathan K. Tyzack, Christopher M. Read
Publikováno v:
Structure. 12(9):1631-1643
The polypyrimidine tract binding protein (PTB) is an important regulator of alternative splicing that also affects mRNA localization, stabilization, polyadenylation, and translation. NMR structural analysis of the N-terminal half of PTB (residues 55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9742009e7fad5de37ef26135fa375402
Publikováno v:
Protein Science. 10:83-98
The fold of the murine Sox-5 (mSox-5) HMG box in free solution has been determined by multidimensional NMR using (15)N-labeled protein and has been found to adopt the characteristic twisted L-shape made up of two wings: the major wing comprising heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ee35e3bd6ff220203dab0dabdd88f0
https://doi.org/10.1110/ps.32801
https://doi.org/10.1110/ps.32801