Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher M. Micklitsch"'
Autor:
Tuna Yucel, Katelyn Nagy-Smith, Darrin J. Pochan, Joel P. Schneider, Scott H. Medina, Christopher M. Micklitsch
Publikováno v:
Macromolecules
Hydrophobic residues provide much of the thermodynamic driving force for the folding, self-assembly, and consequent hydrogelation of amphiphilic β-hairpin peptides. We investigate how the identity of hydrophobic side chains displayed from the hydrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba48aab40f5b61da1d29185269ba145
https://doi.org/10.1021/ma5024796
https://doi.org/10.1021/ma5024796
Autor:
Ronald D. Neumann, Igor G. Panyutin, Mykola I. Onyshchenko, Christopher M. Micklitsch, Pankaj Gupta, Ethan A. Englund, Daniel H. Appella, Evgenia Remeeva
Publikováno v:
ChemBioChem. 15:1887-1890
Recent studies have shown that guanine-rich (G-rich) sequences with the potential to form quadruplexes might play a role in normal transcription as well as overexpression of oncogenes. Chemical tools that allow examination of the specific roles of G-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310767929ec351378af11fd917d684bc
https://doi.org/10.1002/cbic.201402224
https://doi.org/10.1002/cbic.201402224
Publikováno v:
Macromolecules. 41:5763-5772
Triggered hydrogelation of MAX1 peptide, (VK)(4)-V(D)PPT-(KV)(4)-NH(2), proceeds through peptide intramolecular folding into beta-hairpins and concomitant self-assembly into branched clusters of well-defined (uniform, 3 nm cross section), semiflexibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b761f279533d3bfea2ece2eb3d1978c7
https://doi.org/10.1021/ma702840q
https://doi.org/10.1021/ma702840q
Publikováno v:
Tetrahedron Letters. 47:6277-6280
A family of penta- and hexadentate metal ligating α-amino acids, suitably protected for Fmoc solid-phase chemistry, has been prepared. These residues incorporate the mono-amides of ethanolaminetriacetic acid, ethylenediaminetriacetic acid, and ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::366ee12e2115a82a390b7b0c0345b14b
https://doi.org/10.1016/j.tetlet.2006.06.128
https://doi.org/10.1016/j.tetlet.2006.06.128
Autor:
Radhika P. Nagarkar, Monica C. Branco, Joel P. Schneider, Christopher M. Micklitsch, Darrin J. Pochan, Patrick J. Knerr
Publikováno v:
Angew Chem Int Ed Engl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdee116b44e080d61e44648b81cf511d
https://doi.org/10.1002/anie.201006652
https://doi.org/10.1002/anie.201006652
Autor:
David D. Wisnoski, Joseph M. Keane, Ahren I. Green, Jennifer E. Kowalchick, Christopher M. Micklitsch, Amy M. Galka, Chriss E. McDonald
Publikováno v:
Tetrahedron Letters. 42:163-166
A new approach to the generation of acyl radical equivalents has been developed. Treatment of amides with triflic anhydride followed by samarium diiodide allows for cyclization onto appropriately substituted olefins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1851210cfd712b469c73d5a42cbc52ab
https://doi.org/10.1016/s0040-4039(00)01919-5
https://doi.org/10.1016/s0040-4039(00)01919-5
Autor:
Ahren I. Green, David D. Wisnoski, Amy M. Galka, Joseph M. Keane, Chriss E. McDonald, Christopher M. Micklitsch, Jennifer E. Kowalchick
Publikováno v:
ChemInform. 32
A new approach to the generation of acyl radical equivalents has been developed. Treatment of amides with triflic anhydride followed by samarium diiodide allows for cyclization onto appropriately substituted olefins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c9f119a8de82406a3c20188dfeb01b7
https://doi.org/10.1002/chin.200116060
https://doi.org/10.1002/chin.200116060
Autor:
Christopher M. Micklitsch, David D. Roberts, Michael L. Pendrak, Hidetsugu Fujigaki, Deyun Wang, Gema Martin-Manso, Stewart R. Durell, Hiroyasu Sakai, Ethan A. Englund, Rodolfo Ghirlando, Daniel H. Appella
Publikováno v:
Nature communications
Multivalent effects dictate the binding affinity of multiple ligands on one molecular entity to receptors. Integrins are receptors that mediate cell attachment through multivalent binding to peptide sequences within the extracellular matrix, and over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4597bd42a4a5874e4dba88748f3a91a1
http://europepmc.org/articles/PMC3518395
http://europepmc.org/articles/PMC3518395