Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christopher M. Knapp"'
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133154 (2015)
Short interfering ribonucleic acid (siRNA) therapeutics show promise for the treatment of intestinal diseases by specifically suppressing the expression of disease relevant proteins. Recently, a class of lipid-like materials termed "lipidoids" have b
Externí odkaz:
https://doaj.org/article/ab47de8821314ab6b724adea1260b7f7
Publikováno v:
Experimental Biology and Medicine. 244:865-872
Mantle cell lymphoma is an aggressive subtype of non-Hodgkin’s lymphoma that claims the lives of tens of thousands of people every year. Although combination chemotherapy treatments such as CHOP have yielded promising outcomes in the clinic, the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c5f9806093440d415b16e2dda70ab9
https://doi.org/10.1177/1535370219857594
https://doi.org/10.1177/1535370219857594
Publikováno v:
Bioengineering & Translational Medicine
Mantle cell lymphoma is an aggressive and incurable subtype of non‐Hodgkin B cell lymphoma. Patients typically present with advanced disease, and most patients succumb within a decade of diagnosis. There is a clear and urgent need for novel therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bc750d4279646acc4f80f4f1a9c6b3
http://europepmc.org/articles/PMC6063866
http://europepmc.org/articles/PMC6063866
Publikováno v:
Cellular and Molecular Bioengineering. 9:305-314
RNA interference therapeutics have been limited, in large part, by the lack of efficient, non-toxic, non-immunogenic delivery systems. Among previously established methods, lipidoid nanoparticles (LNPs) show particular promise in delivering siRNA to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008a84cba9ba65a459e7f4befb2e67ba
https://doi.org/10.1007/s12195-016-0436-9
https://doi.org/10.1007/s12195-016-0436-9
Autor:
Arsenovic Nebojsa, Peter M. Mota, Alexander J. Brent, Antonella Berry-Brincat, Christopher M. Knapp
Publikováno v:
Canadian Journal of Ophthalmology. 52:e235-e237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf361b4e588adac3f68535eb59b71884
https://doi.org/10.1016/j.jcjo.2017.05.001
https://doi.org/10.1016/j.jcjo.2017.05.001
Publikováno v:
BMC Ophthalmology, Vol 19, Iss 1, Pp 1-3 (2019)
BMC Ophthalmology
BMC Ophthalmology
Background It has been previously reported that one copy of the variable number tandem repeat (VNTR) B alleles of the GPIbα gene increases the risk of non-arteritic ischaemic optic neuropathy (NAION) and the second eye involvement. This is the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438e00fb62e68b945f9f270112a6ac7c
https://doi.org/10.1186/s12886-018-1010-0
https://doi.org/10.1186/s12886-018-1010-0
Autor:
Sarah B. Deluty, Shridhar Singh, Daria Strelkova, Rebecca L. Ball, Khalid A. Hajj, Kathryn A. Whitehead, Christopher M. Knapp
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 15(6)
The potential of mRNA therapeutics will be realized only once safe and effective delivery systems are established. Unfortunately, delivery vehicle development is stymied by an inadequate understanding of how the molecular properties of a vehicle conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0d99515d0e56f84492a682d715cc3e
https://pubmed.ncbi.nlm.nih.gov/30637934
https://pubmed.ncbi.nlm.nih.gov/30637934
Publikováno v:
Expert Opinion on Drug Delivery. 11:1923-1937
Non-Hodgkin lymphoma (NHL) is diagnosed in 70,000 Americans annually. Chemotherapy was the standard course of treatment until the addition of the monoclonal antibody (mAb) drug, rituximab, to therapy regimens in 1997. Although disease prognosis has i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d64908e5385808911ddb08f9355a145
https://doi.org/10.1517/17425247.2014.945419
https://doi.org/10.1517/17425247.2014.945419
Publikováno v:
Strabismus. 21:37-49
Optokinetic nystagmus (OKN) is a reflex eye movement induced by motion of the whole or a large proportion of the visual field. It can be horizontal, vertical, and torsional in direction and consists of two basic components, a slow tracking movement a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5947c72347018ff719f7a62945b5853
https://doi.org/10.3109/09273972.2012.762532
https://doi.org/10.3109/09273972.2012.762532
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0133154 (2015)
PLoS ONE, Vol 10, Iss 7, p e0133154 (2015)
Short interfering ribonucleic acid (siRNA) therapeutics show promise for the treatment of intestinal diseases by specifically suppressing the expression of disease relevant proteins. Recently, a class of lipid-like materials termed "lipidoids" have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eee75a27983965907358065403e6d32
http://europepmc.org/articles/PMC4508104
http://europepmc.org/articles/PMC4508104