Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christopher M. Joslyn"'
Autor:
Andreu Viader, Jacqueline L. Blankman, Peng Zhong, Xiaojie Liu, Joel E. Schlosburg, Christopher M. Joslyn, Qing-Song Liu, Aaron J. Tomarchio, Aron H. Lichtman, Dana E. Selley, Laura J. Sim-Selley, Benjamin F. Cravatt
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 798-808 (2015)
The endocannabinoid 2-arachidonoylglycerol (2-AG) is a retrograde lipid messenger that modulates synaptic function, neurophysiology, and behavior. 2-AG signaling is terminated by enzymatic hydrolysis—a reaction that is principally performed by mono
Externí odkaz:
https://doaj.org/article/a58d2651f0fd4eff8581e58600acdec0
Autor:
Andreu Viader, Daisuke Ogasawara, Christopher M Joslyn, Manuel Sanchez-Alavez, Simone Mori, William Nguyen, Bruno Conti, Benjamin F Cravatt
Publikováno v:
eLife, Vol 5 (2016)
Metabolic specialization among major brain cell types is central to nervous system function and determined in large part by the cellular distribution of enzymes. Serine hydrolases are a diverse enzyme class that plays fundamental roles in CNS metabol
Externí odkaz:
https://doaj.org/article/d5e645537bb8498db55da5346fdc087b
Autor:
Dana E. Selley, Aaron J. Tomarchio, Jacqueline L. Blankman, Xiaojie Liu, Peng Zhong, Joel E. Schlosburg, Christopher M. Joslyn, Benjamin F. Cravatt, Andreu Viader, Laura J. Sim-Selley, Aron H. Lichtman, Qing-song Liu
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 798-808 (2015)
SummaryThe endocannabinoid 2-arachidonoylglycerol (2-AG) is a retrograde lipid messenger that modulates synaptic function, neurophysiology, and behavior. 2-AG signaling is terminated by enzymatic hydrolysis—a reaction that is principally performed
Autor:
Enrique Saez, Kenji Sasaki, Christopher G. Parker, Benjamin F. Cravatt, Arthur S. Kim, Christopher M. Joslyn, Iñigo Narvaiza, Stephen R. Johnson, Cullen L. Cavallaro, Bruno E. Correia, R. Michael Lawrence, Andrea Galmozzi, Yujia Wang
Advances in the synthesis and screening of small-molecule libraries have accelerated the discovery of chemical probes for studying biological processes. Still, only a small fraction of the human proteome has chemical ligands. Here, we describe a plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1c382b32e8161eff4f3f6a348eca99
https://europepmc.org/articles/PMC5632530/
https://europepmc.org/articles/PMC5632530/
Autor:
William Nguyen, Daisuke Ogasawara, Bruno Conti, Simone Mori, Benjamin F. Cravatt, Christopher M. Joslyn, Andreu Viader, Manuel Sanchez-Alavez
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Metabolic specialization among major brain cell types is central to nervous system function and determined in large part by the cellular distribution of enzymes. Serine hydrolases are a diverse enzyme class that plays fundamental roles in CNS metabol