Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Christopher M. Jackson"'
Autor:
Taha Ahmedna, Harmon Khela, Carly Weber-Levine, Tej D. Azad, Christopher M. Jackson, Kathleen Gabrielson, Chetan Bettegowda, Jordina Rincon-Torroella
Publikováno v:
Cancers, Vol 15, Iss 24, p 5784 (2023)
Cell-based immunotherapy for glioblastoma (GBM) encounters major challenges due to the infiltration-resistant and immunosuppressive tumor microenvironment (TME). γδ T cells, unconventional T cells expressing the characteristic γδ T cell receptor,
Externí odkaz:
https://doaj.org/article/fb9245d0f332449083cc8375b5e943a4
Autor:
Ayush Pant, Christopher M. Jackson
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest. Challenges specific to treating solid tumors include trafficking and distr
Externí odkaz:
https://doaj.org/article/19238fcd298140aa90b4e94dfa79a237
Autor:
Ernesto Alfonso-Pita, Edward Behnke, Matthew Bressler, Benjamin Broerman, Kenneth Clark, Jonathan Corbett, C. Eric Dahl, Koby Dering, Austin de St. Croix, Daniel Durnford, Pietro Giampa, Jeter Hall, Orin Harris, Hector Hawley-Herrera, Christopher M. Jackson, Youngtak Ko, Noah Lamb, Mathieu Laurin, Ilan Levine, W. Hugh Lippincott, Xingxin Liu, Russell Neilson, Marie-Cécile Piro, Shashank Priya, Daniel Pyda, Zhiheng Sheng, Gary Sweeney, Eric Vázquez-Jáuregui, Shawn Westerdale, Thomas J. Whitis, Alexander Wright, Wei Zha, Ryan Zhang
Publikováno v:
Universe, Vol 9, Iss 8, p 346 (2023)
The Scintillating Bubble Chamber (SBC) collaboration is developing liquid-noble bubble chambers for the detection of sub-keV nuclear recoils. These detectors benefit from the electron recoil rejection inherent in moderately-superheated bubble chamber
Externí odkaz:
https://doaj.org/article/a20125a1803543f89800a2d9d9067c5b
Autor:
Elizabeth E. Wicks, Kathleen R. Ran, Jennifer E. Kim, Risheng Xu, Ryan P. Lee, Christopher M. Jackson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immune response to ischemic stroke is an area of study that is at the forefront of stroke research and presents promising new avenues for treatment development. Upon cerebral vessel occlusion, the innate immune system is activated by danger-assoc
Externí odkaz:
https://doaj.org/article/d42e1905171f478e92e3bb0d449beb2c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
No portion of this manuscript has previously been presented. Meningiomas, the most common primary intracranial tumors, are histologically categorized by the World Health Organization (WHO) grading system. While higher WHO grade is generally associate
Externí odkaz:
https://doaj.org/article/1d54a5476e354def83cbcfe75e1a5426
Publikováno v:
Cancers, Vol 15, Iss 5, p 1414 (2023)
Glioblastoma (GBM) is the most common primary brain tumor, yet prognosis remains dismal with current treatment. Immunotherapeutic strategies have had limited effectiveness to date in GBM, but recent advances hold promise. One such immunotherapeutic a
Externí odkaz:
https://doaj.org/article/5f01af39ac1348ceb416e324aa3d77ce
Autor:
Russell Maxwell, Andrew S. Luksik, Tomas Garzon-Muvdi, Alice L. Hung, Eileen S. Kim, Adela Wu, Yuanxuan Xia, Zineb Belcaid, Noah Gorelick, John Choi, Debebe Theodros, Christopher M. Jackson, Dimitrios Mathios, Xiaobu Ye, Phuoc T. Tran, Kristin J. Redmond, Henry Brem, Drew M. Pardoll, Lawrence R. Kleinberg, Michael Lim
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
Immune checkpoint blockade targeting programmed cell death protein 1 (PD-1) is emerging as an important treatment strategy in a growing list of cancers, yet its clinical benefits are limited to a subset of patients. Further investigation of tumor-int
Externí odkaz:
https://doaj.org/article/6c9d1d466f094be8842a3615d27c9a5f
Publikováno v:
Cancers, Vol 6, Iss 1, Pp 376-395 (2014)
Signal transducer and activator of transcription 3 (STAT3) is a potent regulator of gliomagenesis through its induction of angiogenesis, host immunosuppression, and tumor invasion. Gain of function mutations result in constitutive activation of STAT3
Externí odkaz:
https://doaj.org/article/6fb0f163d97f4dc9bed94f39e2b004d3
Autor:
Christopher M. Jackson
Publikováno v:
Democratization. :1-26
Autor:
Ryan P. Lee, Meghana Bhimreddy, Jennifer Kim, Robert T. Wicks, Risheng Xu, Matthew Bender, Wuyang Yang, Shahab Aldin Sattari, Alice Hung, Christopher M. Jackson, L. Fernando Gonzalez, Judy Huang, Rafael Tamargo, Cameron G. McDougall, Justin M. Caplan
Publikováno v:
Neurosurgery.