Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christopher M. Bearden"'
Publikováno v:
Journal of Immunological Methods. 300:192-199
Both monoclonal (e.g. Orthoclone (OKT3), rituximab) and polyclonal (e.g. ATGAM, Thymoglobulin (Thymo)) anti-lymphocyte Abs (ALAs) are used extensively in organ transplantation for immunosuppression induction, desensitization, and treatment of acute r
Autor:
Mark D. Pescovitz, Benita K. Book, Richard A. Sidner, Christopher M. Bearden, Avinash Agarwal, Carlos A. Vieira
Publikováno v:
Human Antibodies. 13:55-62
Rituximab, chimeric anti-human CD20 monoclonal antibody approved for B-cell lymphoma, depletes circulating B cells. Little data exist on its use for nonmalignant diseases or B-cell subset recovery after treatment. We hypothesized that rituximab may r
Autor:
Mark D. Pescovitz, Timothy Taber, Michael A. Kraus, Carlos A. Vieira, Christopher M. Bearden, Naomi S. Fineberg, R A Sidner, Howard M. Gebel, Anthony L. Roggero, Benita K. Book, Avinash Agarwal
Publikováno v:
Transplantation. 77:542-548
Background Preformed HLA antibodies (Ab), reported as panel-reactive antibody (PRA), prolong patient waiting time for kidney transplantation. We hypothesized that rituximab (RTX) could reduce PRA via B-cell depletion. This initial study reports the s
Autor:
Kevin A. Thomas, Mitchel B. Harris, Daniel J. Gallagher, Christopher M. Bearden, M Alan Hinton
Publikováno v:
Orthopedics. 20:51-57
A tibial shaft fracture model was created to study the effects of an intramedullary nail and partial fibulectomy on fracture loading. Cadaveric lower extremities were instrumented with strain gages and subjected to biomechanical testing. A nonreamed
The Effect of Anterior Thoracolumbar Plate Application on the Compressive Loading of the Strut Graft
Publikováno v:
Spine. 21:1487-1493
Study Design In vitro biomechanical testing was performed using a simulated vertebral body bone graft instrumented with strain gauges. Strains were recorded from various locations on the graft during axial compressive loading. Comparisons were made o
Autor:
A.B. Milgrom, Nancy G. Higgins, Christopher M. Bearden, Mark D. Pescovitz, R A Sidner, Benita K. Book, Avinash Agarwal
Publikováno v:
Transplantation proceedings. 37(2)
Humanized and chimeric antilymphocyte antibodies (Ab) are used to prevent and treat rejection and for treatment of human disease. Rituximab (RIT, anti-CD20), daclizumab (DAC; anti-CD25), alemtuzumab (ALE; anti-CD52), or infliximab (IFX) may interfere
Autor:
Marquerite Young, Mark D. Pescovitz, Carlos A. Vieira, Christopher M. Bearden, R A Sidner, Benita K. Book, Avinash Agarwal, Hans D. Ochs
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5(1)
The response to primary immunization in patients treated with Rituximab (RIT) is not clear. We studied the in vivo antibody response of chronic renal failure (CRF) patients to the neoantigen bacteriophage phiX174 given alone or after ablation with RI
Autor:
Richard A, Sidner, Benita K, Book, Avinash, Agarwal, Christopher M, Bearden, Carlos A, Vieira, Mark D, Pescovitz
Publikováno v:
Human antibodies. 13(3)
Rituximab, chimeric anti-human CD20 monoclonal antibody approved for B-cell lymphoma, depletes circulating B cells. Little data exist on its use for nonmalignant diseases or B-cell subset recovery after treatment. We hypothesized that rituximab may r
Autor:
Howard M. Gebel, Mark D. Pescovitz, Christopher M. Bearden, Benita K. Book, Avinash Agarwal, R A Sidner, Robert A. Bray
Publikováno v:
Human immunology. 65(8)
Rituximab (RIT), a murine/human chimeric monoclonal antibody directed against human CD20 is under investigation for its role in transplantation. RIT causes B-cell crossmatches to appear positive. Pronase, a proteolytic enzyme that targets F(c) recept
Autor:
Mark D. Pescovitz, R A Sidner, Nancy G. Higgins, Benita K. Book, Avinash Agarwal, Christopher M. Bearden
Publikováno v:
Transplantation. 78:191