Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christopher M. Arian"'
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Pharmacol Ther
The intestine has important gate-keeping functions that can profoundly affect the systemic blood exposure of orally administered drugs. Thus, characterizing a new molecular entity's (NME) disposition within the intestine is of utmost importance in dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a8d0cd624332dd5b0dca2bd21411c0
https://europepmc.org/articles/PMC8821120/
https://europepmc.org/articles/PMC8821120/
Autor:
Deena L. Hadi, Rakshit S. Tanna, Jashvant D. Unadkat, Mary F. Paine, Nadja B. Cech, Sumit Bansal, Justina C. Calamia, Matthew E. Layton, Kenneth E. Thummel, Dan-Dan Tian, Miklós Horváth, Christopher M. Arian, Bálint Molnár, Joshua J. Kellogg, Laura M. Shireman, John R. White, James Nguyen, Richard D. Boyce
Publikováno v:
Clin Pharmacol Ther
The botanical natural product goldenseal can precipitate clinical drug interactions by inhibiting cytochrome P450 (CYP) 3A and CYP2D6. Besides P-glycoprotein, effects of goldenseal on other clinically relevant transporters remain unknown. Established