Zobrazeno 1 - 10 of 318 pro vyhledávání: '"Christopher M. Hadad"'
1
Akademický článek
Identification of Corrosive Volatile Compounds Found in the Headspace of Chicken Noodle Soup Retorted in Metal Cans
Autor: Yajun Wu, Ken Ruffley, Elliot Dhuey, Christopher M. Hadad, Melvin A. Pascall
Publikováno v: International Journal of Food Science, Vol 2023 (2023)
This study investigated the development of volatile compounds in the headspace of canned chicken noodle soup (and sought to develop appropriate testing methods). The primary objective of this study was to identify compounds in the soup that were resp
Externí odkaz: https://doaj.org/article/a4217f842671457a93dcdc8490342a32
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2
Akademický článek
Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors
Autor: Thomas S. Corrigan, Leilani M. Lotti Diaz, Sarah E. Border, Steven C. Ratigan, Kayla Q. Kasper, Daniel Sojka, Pavla Fajtova, Conor R. Caffrey, Guy S. Salvesen, Craig A. McElroy, Christopher M. Hadad, Özlem Doğan Ekici
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1387-1402 (2020)
Aza-peptide aldehydes and ketones are a new class of reversible protease inhibitors that are specific for the proteasome and clan CD cysteine proteases. We designed and synthesised aza-Leu derivatives that were specific for the chymotrypsin-like acti
Externí odkaz: https://doaj.org/article/31bf5971d3b54bc09b1c70a575cfb101
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8
Enantioselective Dearomative Alkynylation of Chromanones: Opportunities and Obstacles
Autor: Anita E. Mattson, Yong Guan, Tadas Buivydas, Remy F. Lalisse, Rameez Ali, Christopher M. Hadad
Publikováno v: Synthesis. 54:4210-4219
A catalytic and highly enantioselective dearomative alkynylation of chromanones has been discovered that enables the construction of biologically relevant tertiary ether stereogenic centers. This methodology is robust, accommodating a variety of alky
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::789f7fcf56d2c1f8a5bd6bdf40688fe0
https://doi.org/10.1055/a-1811-8075
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10
In-silico guided design, screening, and molecular dynamic simulation studies for the identification of potential SARS-CoV-2 main protease inhibitors for the targeted treatment of COVID-19
Autor: Gopichand Gutti, Yiran He, William H. Coldren, Remy F. Lalisse, Sarah E. Border, Christopher M. Hadad, Craig A. McElroy, Özlem Doğan Ekici
COVID-19, the disease responsible for the recent pandemic, is caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The main protease (Mpro) of SARS-CoV-2 is an essential proteolytic enzyme that plays a number of important r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a392304df02a1f698538218332a778
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