Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Christopher M Yengo"'
Autor:
David V Rasicci, Prince Tiwari, Skylar ML Bodt, Rohini Desetty, Fredrik R Sadler, Sivaraj Sivaramakrishnan, Roger Craig, Christopher M Yengo
Publikováno v:
eLife, Vol 11 (2022)
The auto-inhibited, super-relaxed (SRX) state of cardiac myosin is thought to be crucial for regulating contraction, relaxation, and energy conservation in the heart. We used single ATP turnover experiments to demonstrate that a dilated cardiomyopath
Externí odkaz:
https://doaj.org/article/2a972567fd55436c8074580ba6a5c3a8
Autor:
Haiyang Liu, Jianchao Li, Manmeet H Raval, Ningning Yao, Xiaoying Deng, Qing Lu, Si Nie, Wei Feng, Jun Wan, Christopher M Yengo, Wei Liu, Mingjie Zhang
Publikováno v:
eLife, Vol 5 (2016)
Class III myosins (Myo3) and actin-bundling protein Espin play critical roles in regulating the development and maintenance of stereocilia in vertebrate hair cells, and their defects cause hereditary hearing impairments. Myo3 interacts with Espin1 th
Externí odkaz:
https://doaj.org/article/6de15ef6e119415f95f2c8669a0348b7
Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins.
Autor:
Kirk L Mecklenburg, Stephanie A Freed, Manmeet Raval, Omar A Quintero, Christopher M Yengo, Joseph E O'Tousa
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122502 (2015)
In Drosophila photoreceptors, the NINAC-encoded myosin III is found in a complex with a small, MORN-repeat containing, protein Retinophilin (RTP). Expression of these two proteins in other cell types showed NINAC myosin III behavior is altered by RTP
Externí odkaz:
https://doaj.org/article/ad8eed47e1fe415c98371b8468ea12da
Autor:
Seham Ebrahim, Matthew R. Avenarius, M’hamed Grati, Jocelyn F. Krey, Alanna M. Windsor, Aurea D. Sousa, Angela Ballesteros, Runjia Cui, Bryan A. Millis, Felipe T. Salles, Michelle A. Baird, Michael W. Davidson, Sherri M. Jones, Dongseok Choi, Lijin Dong, Manmeet H. Raval, Christopher M. Yengo, Peter G. Barr-Gillespie, Bechara Kachar
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Stereocilia of the inner ear have graded heights that are thought to be regulated by the myosin-III family members MYO3A and MYO3B. Here the authors identify espin-1 and espin-like (ESPNL) as cargo that differentially influence the functions of both
Externí odkaz:
https://doaj.org/article/42f55193d572437c9f31dff7d2836595
Autor:
Matthew H. Doran, Michael J. Rynkiewicz, David Rasicci, Skylar M.L. Bodt, Meaghan E. Barry, Esther Bullitt, Christopher M. Yengo, Jeffrey R. Moore, William Lehman
Publikováno v:
Journal of General Physiology. 155
Following binding to the thin filament, β-cardiac myosin couples ATP-hydrolysis to conformational rearrangements in the myosin motor that drive myofilament sliding and cardiac ventricular contraction. However, key features of the cardiac-specific ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6b6bf684fbbd474adf1942c0195791
https://doi.org/10.1085/jgp.202213267
https://doi.org/10.1085/jgp.202213267
Autor:
Matthew H. Doran, Michael J. Rynkiewicz, Elumalai Pavadai, Skylar M.L. Bodt, David Rasicci, Jeffrey R. Moore, Christopher M. Yengo, Esther Bullitt, William Lehman
Publikováno v:
Journal of General Physiology. 155
During force-generating steps of the muscle crossbridge cycle, the tip of the myosin motor, specifically loop-4, contacts the tropomyosin cable of actin filaments. In the current study, we determined the corresponding effect of myosin loop-4 on the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27195f87c903ace2e2bf94b595b53c11
https://doi.org/10.1085/jgp.202213274
https://doi.org/10.1085/jgp.202213274
Publikováno v:
Biophys J
Cardiac muscle contraction is driven by the molecular motor myosin, which uses the energy from ATP hydrolysis to generate a power stroke when interacting with actin filaments, although it is unclear how this mechanism is impaired by mutations in myos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892f06a0a71aae7a1e73927aff41fb39
https://doi.org/10.1016/j.bpj.2021.04.007
https://doi.org/10.1016/j.bpj.2021.04.007
The role of myosin loop-4 in localizing tropomyosin on actin during muscle activation and relaxation
Autor:
Matthew Doran, Michael J. Rynkiewicz, Elumalai Pavadai, Skylar M.L. Bodt, Dave Rasicci, Jeffrey R. Moore, Esther Bullitt, Christopher M. Yengo, William Lehman
Publikováno v:
Biophysical Journal. 122:401a-402a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9e5d937669a6cb2b4f67442a610c294
https://doi.org/10.1016/j.bpj.2022.11.2189
https://doi.org/10.1016/j.bpj.2022.11.2189
Autor:
David V Rasicci, Prince Tiwari, Skylar ML Bodt, Rohini Desetty, Fredrik R Sadler, Sivaraj Sivaramakrishnan, Roger Craig, Christopher M Yengo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d666a9f4e73b507afa727aa42d6fe91
https://doi.org/10.7554/elife.77415.sa2
https://doi.org/10.7554/elife.77415.sa2
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Corey Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Richard Schulz, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1147fd54b772479d3c37403d3f13bf41
https://doi.org/10.1096/fasebj.2022.36.s1.0r342
https://doi.org/10.1096/fasebj.2022.36.s1.0r342