Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christopher M Yellman"'
Autor:
Zachory M Park, Abigail J Sporer, Katherine Kraft, Krystal K Lum, Edith Blackman, Ethan Belnap, Christopher M Yellman, Mark D Rose
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010896 (2023)
KAR4, the yeast homolog of the mammalian mRNA N6A-methyltransferase complex component METTL14, is required for two disparate developmental programs in Saccharomyces cerevisiae: mating and meiosis. To understand KAR4's role in yeast mating and meiosis
Externí odkaz:
https://doaj.org/article/04a060d5f391487a8c1f925cbf8232fc
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128604 (2015)
Cdc14 phosphatase is a key regulator of exit from mitosis, acting primarily through antagonism of cyclin-dependent kinase, and is also thought to be important for meiosis. Cdc14 is released from its sequestration site in the nucleolus in two stages,
Externí odkaz:
https://doaj.org/article/39dc1a4801e7422c83af066a3fc8963f
Autor:
Philippe Lefrançois, Raymond K Auerbach, Christopher M Yellman, G Shirleen Roeder, Michael Snyder
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003209 (2013)
Accurate chromosome segregation requires centromeres (CENs), the DNA sequences where kinetochores form, to attach chromosomes to microtubules. In contrast to most eukaryotes, which have broad centromeres, Saccharomyces cerevisiae possesses sequence-d
Externí odkaz:
https://doaj.org/article/e82f5647b12a480f914928788a9a597d
Autor:
Christopher M. Yellman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3189-3200 (2020)
Artificial induction of a chromosomal double-strand break in Saccharomyces cerevisiae enhances the frequency of integration of homologous DNA fragments into the broken region by up to several orders of magnitude. The process of homologous repair can
Externí odkaz:
https://doaj.org/article/86682078d3ac4e9fa0a0b338b6f0bb10
Autor:
Christopher M. Yellman
Eukaryotic meiosis is a specialized cell cycle involving two successive nuclear divisions that lead to the formation of haploid gametes. The phosphatase Cdc14 plays an essential role in meiosis as revealed in studies of the yeastSaccharomyces cerevis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d725183fb9b2eed2286293dd8e774003
https://doi.org/10.1101/2021.02.15.431250
https://doi.org/10.1101/2021.02.15.431250
Autor:
Christopher M, Yellman
Publikováno v:
G3: Genes|Genomes|Genetics
Artificial induction of a chromosomal double-strand break in Saccharomyces cerevisiae enhances the frequency of integration of homologous DNA fragments into the broken region by up to several orders of magnitude. The process of homologous repair can
Autor:
Andreas T Matouschek, Houqing Yu, Adrian H. Elcock, Christopher M. Yellman, Amit Kumar Singh Gautam
The proteasome establishes protein homeostasis by selectively degrading cellular proteins. There are two main prerequisites for a protein to be selected for proteasomal degradation: a ubiquitin tag covalently attached to the protein and a disordered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b80f059fa4f46e8a93cc6ece3e4e27d7
https://doi.org/10.21203/rs.3.rs-38559/v1
https://doi.org/10.21203/rs.3.rs-38559/v1
Publikováno v:
The EMBO Journal. 35:1522-1536
Ubiquitin and some of its homologues target proteins to the proteasome for degradation. Other ubiquitin-like domains are involved in cellular processes unrelated to the proteasome, and proteins containing these domains remain stable in the cell. We f
Autor:
Edward M. Barbieri, Christopher M. Yellman, Farren J. Isaacs, Paul R. Muir, Benjamin O. Akhuetie-Oni
We describe a multiplex genome engineering technology in Saccharomyces cerevisiae based on annealing synthetic oligonucleotides at the lagging strand of DNA replication. The mechanism is independent of Rad51-directed homologous recombination and avoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab231d6f1c40141e501d7ea0fd26670
https://europepmc.org/articles/PMC5995112/
https://europepmc.org/articles/PMC5995112/
Autor:
Christopher M. Yellman, Aashiq H. Kachroo, Edward M. Marcotte, Yufeng Qian, Kenneth A. Johnson
Publikováno v:
Journal of Biological Chemistry. 289:5970-5985
Mutations in the human mitochondrial polymerase (polymerase-γ (Pol-γ)) are associated with various mitochondrial disorders, including mitochondrial DNA (mtDNA) depletion syndrome, Alpers syndrome, and progressive external opthamalplegia. To correla