Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Christopher M Nutting"'
Autor:
Marco Borri, Maria A Schmidt, Ceri Powell, Dow-Mu Koh, Angela M Riddell, Mike Partridge, Shreerang A Bhide, Christopher M Nutting, Kevin J Harrington, Katie L Newbold, Martin O Leach
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138545 (2015)
PURPOSE:To describe a methodology, based on cluster analysis, to partition multi-parametric functional imaging data into groups (or clusters) of similar functional characteristics, with the aim of characterizing functional heterogeneity within head a
Externí odkaz:
https://doaj.org/article/0188356f33854b9cb081b39028b4680d
Autor:
Shane Zaidi, Martin McLaughlin, Shreerang A Bhide, Suzanne A Eccles, Paul Workman, Christopher M Nutting, Robert A Huddart, Kevin J Harrington
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35436 (2012)
Heat shock protein 90 (HSP90) is a molecular chaperone responsible for the conformational maintenance of a number of client proteins that play key roles in cell cycle arrest, DNA damage repair and apoptosis following radiation. HSP90 inhibitors exhib
Externí odkaz:
https://doaj.org/article/08a586a1c76b454e94482aefa4f9bc63
Autor:
Kevin J. Harrington, Martin McLaughlin, Christopher M. Nutting, Kate L. Newbold, Shreerang A. Bhide, Hind Hafsi, Malin Pedersen, Holly E. Barker, Magnus T. Dillon
Supplementary figures 1-4, supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d33e773df37337cb3f3754278872ff2
https://doi.org/10.1158/1535-7163.22508769.v1
https://doi.org/10.1158/1535-7163.22508769.v1
Autor:
Kevin J. Harrington, Shreerang Bhide, Katie L. Newbold, Christopher M. Nutting, Shane Zaidi, Ulrike Schick, Martin McLaughlin, Radhika Patel, Holly E. Barker
Supplementary Table S1 and 6 Supplementary Figures, S1-6. Table S1 - Patient samples from the PredictR-HNC study. Figure S1 - CCT244747 and paclitaxel IC50 determination and analysis of CCT244747 combination therapies. Figure S2 - Investigation of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595fd4dd96faae508d1d29c38e422bfc
https://doi.org/10.1158/1535-7163.22503486.v1
https://doi.org/10.1158/1535-7163.22503486.v1
Autor:
Kevin J. Harrington, Georges Vassaux, Richard G. Vile, Alan A. Melcher, Hardev S. Pandha, Christopher M. Nutting, Martin E. Gore, Inge Peerlinck, Andrew Merron, Shane Zaidi, Christine L. White, Mohan Hingorani
Purpose: To assess the effects of external beam radiotherapy (EBRT) on adenoviral-mediated transgene expression in vitro and in vivo and to define an optimal strategy for combining sodium iodide symporter (NIS)–mediated 131I therapy with EBRT.Exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449ac83049bcec6287f6758d26dda7f3
https://doi.org/10.1158/1078-0432.c.6516979.v1
https://doi.org/10.1158/1078-0432.c.6516979.v1
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
T2*-weighted image (TE=4.9 ms) for a stage IV HNSCC patient (Pt No: 5). Marker lines represent image positions used in the assessment of motion correction. B: Time traces of nodal (LN) and primary (P) projections without (S(t)) and with motion correc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a0fc1cffd8aea96bd715427f0cf34b
https://doi.org/10.1158/1078-0432.22467875
https://doi.org/10.1158/1078-0432.22467875
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Scatter plots comparing individual MRI measurements (tumor volume, baseline R2* and percentage of fluctuating volume) against pathology (Hoechst 33342 uptake for perfusion, pimonidazole adduct formation for hypoxia) determined from the cohort of CALR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5643aca51f2f005b04bc89db1f4677
https://doi.org/10.1158/1078-0432.22467878
https://doi.org/10.1158/1078-0432.22467878
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Fluctuating volume percentages detected for HNSCC metastatic lymph node ROIs between two MR sessions 48 hours apart (solid lines - responders, dashed lines - non responders).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326904d68cc016e10569a6c3076ba96c
https://doi.org/10.1158/1078-0432.22467863
https://doi.org/10.1158/1078-0432.22467863
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Examples of Ktrans and R2* distributions for fluctuating and non-fluctuating parts of human HNSCC (Patient No 5, N2). The non-enhancing part of the tumor (Ktrans = 0) is indicated with an asterisk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a8b62ffcddd331f0a69c8105b7a2cd
https://doi.org/10.1158/1078-0432.22467866.v1
https://doi.org/10.1158/1078-0432.22467866.v1
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Supplementary Figure Captions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e3ee10ce1fa4105377b3497c65b7e2
https://doi.org/10.1158/1078-0432.22467860
https://doi.org/10.1158/1078-0432.22467860