Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Christopher M Hovens"'
Autor:
Lucy Vivash, Dennis Velakoulis, Patrick Carney, Patrick Kwan, Leonid Churilov, Terence J O’Brien, Christopher M Hovens, Nicholas Lawn, Piero Perucca, Sandy R Shultz, John-Paul Nicolo, Charles Malpas, Manori Wijayath, David Reutens, Hannah Johns, Sara MacPhail, Pablo Casillas-Espinosa, Chris Tailby, Lisa Gillinder
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Epilepsy is one of the most common neurological conditions worldwide. Despite many antiseizure medications (ASMs) being available, up to one-third of patients do not achieve seizure control. Preclinical studies have shown treatment with
Externí odkaz:
https://doaj.org/article/3fd64e9e8e8b4ff9b7e3d63e337655c5
Autor:
Chol-Hee Jung, Paul C Boutros, Daniel J Park, Niall M Corcoran, Bernard J Pope, Christopher M Hovens
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273783 (2022)
The question of whether it is appropriate to attribute authorship to deceased individuals of original studies in the biomedical literature is contentious. Authorship guidelines utilized by journals do not provide a clear consensus framework that is b
Externí odkaz:
https://doaj.org/article/6122502cc98e410ab988b4f29beea21e
Autor:
Lucy Vivash, Dennis Velakoulis, Terence J O’Brien, Charles B Malpas, Amy Brodtmann, Christopher M Hovens, Steven Collins, Stephen Macfarlane
Publikováno v:
BMJ Neurology Open, Vol 3, Iss 2 (2021)
Introduction Sodium selenate is a potential disease-modifying treatment for Alzheimer’s disease (AD) which reduces hyperphosphorylated tau through activation of the protein phosphatase 2A enzyme. We have shown sodium selenate to be safe and well to
Externí odkaz:
https://doaj.org/article/c635a5b7fee8411fa1aea2b913960bf3
Autor:
Stefano Mangiola, Ryan Stuchbery, Patrick McCoy, Ken Chow, Natalie Kurganovs, Michael Kerger, Anthony Papenfuss, Christopher M Hovens, Niall M Corcoran
Publikováno v:
Endocrine Connections, Vol 8, Iss 5, Pp 547-558 (2019)
Prostate cancer is a leading cause of morbidity and cancer-related death worldwide. Androgen deprivation therapy (ADT) is the cornerstone of management for advanced disease. The use of these therapies is associated with multiple side effects, includi
Externí odkaz:
https://doaj.org/article/1cdeccad257a49f6bf735622768dbe59
Autor:
Rebekah M Ahmed, Lucy Vivash, Dennis Velakoulis, Leonid Churilov, Olivier Piguet, David Darby, Charles B Malpas, Amy Brodtmann, Ashley I Bush, Christopher M Hovens, T Kalincik
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Introduction Behavioural variant frontotemporal dementia (bvFTD) is a neurodegenerative disorder often neuropathologically associated with the accumulation of abnormally hyperphosphorylated tau, for which there is currently no disease-modifying treat
Externí odkaz:
https://doaj.org/article/e73d7ab59c06481ea1a9081344c57033
Autor:
Nikhil Sapre, Matthew K H Hong, Geoff Macintyre, Heather Lewis, Adam Kowalczyk, Anthony J Costello, Niall M Corcoran, Christopher M Hovens
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e91729 (2014)
PurposeThe purpose of this study was to determine if microRNA profiling of urine and plasma at radical prostatectomy can distinguish potentially lethal from indolent prostate cancer.Materials and methodsA panel of microRNAs was profiled in the plasma
Externí odkaz:
https://doaj.org/article/fc3fb7597ee44c4986adddbe3b14bec3
Autor:
Patrick J. McCoy, Anthony J. Costello, Niall M. Corcoran, Christopher M. Hovens, Michael J. Clarkson
Publikováno v:
MethodsX, Vol 6, Iss , Pp 22-34 (2019)
DNA-fluorescence in situ hybridisation (DNA-FISH) allows visualisation of chromosome organisation and rearrangement. FISH probes are pools of short fluorescently labelled DNA fragments that are often produced from template plasmids that contain large
Externí odkaz:
https://doaj.org/article/315081ce01e54bff8ad9b9f56810a674
Autor:
Kathleen E Houlahan, Julie Livingstone, Natalie S Fox, Natalie Kurganovs, Helen Zhu, Jocelyn Sietsma Penington, Chol-Hee Jung, Takafumi N Yamaguchi, Lawrence E Heisler, Richard Jovelin, Anthony J Costello, Bernard J Pope, Amar U Kishan, Niall M Corcoran, Robert G Bristow, Sebastian M Waszak, Joachim Weischenfeldt, Housheng H He, Rayjean J Hung, Christopher M Hovens, Paul C Boutros
Publikováno v:
JNCI: Journal of the National Cancer Institute. 115:468-472
Prostate cancer is one of the most heritable cancers. Hundreds of germline polymorphisms have been linked to prostate cancer diagnosis and prognosis. Polygenic risk scores can predict genetic risk of a prostate cancer diagnosis. Although these scores
Phase 2 Study of Neoadjuvant FGFR Inhibition and Androgen Deprivation Therapy Prior to Prostatectomy
Autor:
Elizabeth Liow, Nicholas Howard, Chol-Hee Jung, Bernard Pope, Bethany K. Campbell, Anne Nguyen, Michael Kerger, Jonathan B. Ruddle, Angelyn Anton, Benjamin Thomas, Kevin Chu, Philip Dundee, Justin S. Peters, Anthony J. Costello, Andrew S. Ryan, Christopher M. Hovens, Ben Tran, Niall M. Corcoran
Publikováno v:
Clinical Genitourinary Cancer. 20:452-458
Disease recurrence is common following prostatectomy in patients with localised prostate cancer with high-risk features. Although androgen deprivation therapy increases the rates of organ-confined disease and negative surgical margins, there is no si
Autor:
Yangyi Zhang, Bethany K. Campbell, Stanley S. Stylli, Niall M. Corcoran, Christopher M. Hovens
Publikováno v:
Uro. 2:74-92
Advanced prostate cancers have a poor survival rate and a lack of effective treatment options. In order to broaden the available treatments, immunotherapies have been investigated. These include cancer vaccines, immune checkpoint inhibitors, chimeric