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Publikováno v: Virulence, Vol 12, Iss 1, Pp 1629-1646 (2021)

Influenza is a respiratory viral infection that causes significant morbidity and mortality worldwide. The innate immune cell response elicited during influenza A virus (IAV) infection forms the critical first line of defense, which typically is impai

Externí odkaz: https://doaj.org/article/571b4da6a54940f98084b3b7d17e1e0d

Unconventional T Cell Immunity in the Lungs of Young Children with Cystic Fibrosis

Autor: Rebecca McElroy, Ghazal Alipour Talesh, Christopher M. Harpur, Rosemary Carzino, Alexandra J. Corbett, Daniel G. Pellicci, Sarath Ranganathan, Philip Sutton

Publikováno v: Frontiers in Bioscience-Landmark, Vol 27, Iss 5, p 149 (2022)

Background: People with Cystic Fibrosis (CF) develop pulmonary inflammation, chronic infection and structural lung damage early in life, with these manifestations being prevalent among preschool children and infants. While early immune events are bel

Externí odkaz: https://doaj.org/article/e5509958a00a4c5186e5d058ea22db5d

Interleukin‐1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection

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Publikováno v: Immunology and Cell Biology

Hyperinflammatory responses including the production of NLRP3‐dependent interleukin (IL)‐1β is a characteristic feature of severe and fatal influenza A virus (IAV) infections. The NLRP3 inflammasome has been shown to play a temporal role during

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https://doi.org/10.1111/imcb.12459

Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d

Autor: Catriona V. Nguyen-Robertson, Spencer J. Williams, D. Branch Moody, Shihan Li, Dale I. Godfrey, Sidonia B G Eckle, Dylan G.M. Smith, Tan-Yun Cheng, Tram Nguyen, Scott J. J. Reddiex, Christopher M. Harpur, Jamie Rossjohn, Elena Batleska, Tamara Thelemann, Adam P Uldrich, Ildiko Van Rhijn, Daniel G. Pellicci, Catarina F. Almeida

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 118(34), 1. National Academy of Sciences
Proc Natl Acad Sci U S A

Natural killer T (NKT) cells detect lipids presented by CD1d. Most studies focus on type I NKT cells that express semi-invariant αβ T cell receptors (TCR) and recognize α-galactosylceramides. However, CD1d also presents structurally distinct lipid

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https://doi.org/10.1073/pnas.2104420118

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Levings, Susanne Melzer, Dinko Pavlinic, Christopher M. Harpur, Christina Stehle, A. Graham Pockley, Toshinori Nakayama, Attila Tárnok, Juhao Yang, Michael Lohoff, Paulo Vieira, Francisco Sala-de-Oyanguren, Christian Kurts, Anastasia Gangaev, Alfonso Blanco, Hans Scherer, Regine J. Dress, Bruno Silva-Santos, Kiyoshi Takeda, Bimba F. Hoyer, Ilenia Cammarata, Daryl Grummitt, Isabel Panse, Günnur Deniz, Bianka Baying, Friederike Ebner, Esther Schimisky, Leo Hansmann, Thomas Kamradt, Edwin van der Pol, Daniel Scott-Algara, Anna Iannone, Giorgia Alvisi, Sebastian R. Schulz, Francesco Liotta, Irmgard Förster, Beatriz Jávega, Hans-Peter Rahn, Caetano Reis e Sousa, Livius Penter, Xuetao Cao, David P. Sester, Keisuke Goda, Peter Wurst, Iain B. McInnes, Ricardo T. Gazzinelli, Federica Piancone, Gerald Willimsky, Yotam Raz, Pärt Peterson, Wolfgang Fritzsche, Yvonne Samstag, Martin Büscher, Thomas Schüler, Susanne Hartmann, Robert J. Wilkinson, Anna E. S. Brooks, Steven L. C. Ketelaars, Catherine Sautès-Fridman, Anna Rubartelli, Petra Bacher, Katja Kobow, Marco A. Cassatella, Andrea Hauser, Henrik E. Mei, Kilian Schober, Silvia Della Bella, Graham Anderson, Michael D. Ward, Garth Cameron, Sebastian Lunemann, Katharina Kriegsmann, Katarzyna M. Sitnik, Brice Gaudilliere, Chantip Dang-Heine, Marcello Pinti, Paul Klenerman, Frank A. Schildberg, Joana Barros-Martins, Laura G. Rico, Hanlin Zhang, Christian Münz, Thomas Dörner, Jakob Zimmermann, Andrea M. Cooper, Jonni S. Moore, Andreas Diefenbach, Yanling Liu, Wolfgang Bauer, Tobit Steinmetz, Katharina Pracht, Leonard Tan, Peter K. Jani, Alan M. Stall, Petra Hoffmann, Christine S. Falk, Jasmin Knopf, Simon Fillatreau, Hans-Dieter Volk, Luis E. Muñoz, David L. Haviland, William W. Agace, Jonathan Rebhahn, Ljiljana Cvetkovic, Mohamed Trebak, Jordi Petriz, Mario Clerici, Diether J. Recktenwald, Anders Ståhlberg, Tristan Holland, Helen M. McGuire, Sa A. Wang, Christian Kukat, Thomas Kroneis, Laura Cook, Wan Ting Kong, Xin M. Wang, Britta Engelhardt, Pierre Coulie, Genny Del Zotto, Sally A. Quataert, Kata Filkor, Gabriele Multhoff, Bartek Rajwa, Federica Calzetti, Hans Minderman, Cosima T. Baldari, Jens Geginat, Hervé Luche, Gert Van Isterdael, Linda Schadt, Sophia Urbanczyk, Giovanna Borsellino, Liping Yu, Dale I. Godfrey, Achille Anselmo, Rachael C. Walker, Andreas Grützkau, David W. Hedley, Birgit Sawitzki, Silvia Piconese, Maria Yazdanbakhsh, Burkhard Becher, Ramon Bellmas Sanz, Michael Delacher, Hyun-Dong Chang, Immanuel Andrä, Hans-Gustaf Ljunggren, José-Enrique O'Connor, Ahad Khalilnezhad, Sharon Sanderson, Federico Colombo, Götz R. A. Ehrhardt, Inga Sandrock, Enrico Lugli, Christian Bogdan, James B. Wing, Susann Müller, Tomohiro Kurosaki, Derek Davies, Ester B. M. Remmerswaal, Kylie M. Quinn, Christopher A. Hunter, Andreas Radbruch, Timothy P. Bushnell, Anna Erdei, Sabine Adam-Klages, Pascale Eede, Van Duc Dang, Rieke Winkelmann, Thomas Korn, Gemma A. Foulds, Dirk Baumjohann, Matthias Schiemann, Manfred Kopf, Jan Kisielow, Lisa Richter, Jochen Huehn, Gloria Martrus, Alexander Scheffold, Jessica G. Borger, Sidonia B G Eckle, John Bellamy Foster, Anna Katharina Simon, Alicia Wong, Mübeccel Akdis, Gisa Tiegs, Toralf Kaiser, James McCluskey, Anna Vittoria Mattioli, Aaron J. Marshall, Hui-Fern Koay, Eva Orlowski-Oliver, Anja E. Hauser, J. Paul Robinson, Jay K. Kolls, Luca Battistini, Mairi McGrath, Jane L. Grogan, Natalio Garbi, Timothy Tree, Kingston H. G. Mills, Stefan H. E. Kaufmann, Wolfgang Schuh, Ryan R. Brinkman, Tim R. Mosmann, Vincenzo Barnaba, Andreas Dolf, Lorenzo Cosmi, Bo Huang, Andreia C. Lino, Baerbel Keller, René A. W. van Lier, Alexandra J. Corbett, Paul S. Frenette, Pleun Hombrink, Helena Radbruch, Sofie Van Gassen, Olivier Lantz, Lorenzo Moretta, Désirée Kunkel, Kirsten A. Ward-Hartstonge, Armin Saalmüller, Leslie Y. T. Leung, Salvador Vento-Asturias, Paola Lanuti, Alicia Martínez-Romero, Sarah Warth, Zhiyong Poon, Diana Dudziak, Andrea Cossarizza, Kovit Pattanapanyasat, Konrad von Volkmann, Jessica P. Houston, Agnès Lehuen, Andrew Filby, Pratip K. Chattopadhyay, Stefano Casola, Annika Wiedemann, Hannes Stockinger, Jürgen Ruland, Arturo Zychlinsky, Claudia Waskow, Katrin Neumann, Ari Waisman, Lucienne Chatenoud, Sudipto Bari, Kamran Ghoreschi, David W. Galbraith, Yvan Saeys, Hamida Hammad, Andrea Gori, Miguel López-Botet, Gabriel Núñez, Sabine Ivison, Michael Hundemer, Dorothea Reimer, Mark C. Dessing, Günter J. Hämmerling, Rudolf A. Manz, Tomas Kalina, Jonas Hahn, Holden T. Maecker, Hendy Kristyanto, Martin S. Davey, Henning Ulrich, Michael L. Dustin, Takashi Saito, Yousuke Takahama, Milena Nasi, Johanna Huber, Jürgen Wienands, Paolo Dellabona, Andreas Schlitzer, Michael D. Leipold, Kerstin H. Mair, Christian Peth, Immo Prinz, Chiara Romagnani, José M. González-Navajas, Josephine Schlosser, Marina Saresella, Matthias Edinger, Dirk Brenner, Nicole Baumgarth, Rikard Holmdahl, Fang-Ping Huang, Guadalupe Herrera, Malte Paulsen, Gergely Toldi, Luka Cicin-Sain, Reiner Schulte, Christina E. Zielinski, Thomas Winkler, Christoph Goettlinger, Philip E. Boulais, Jennie H M Yang, Antonio Celada, Heike Kunze-Schumacher, Julia Tornack, Florian Ingelfinger, Jenny Mjösberg, Andy Riddell, Leonie Wegener, Thomas Höfer, Christoph Hess, James P. Di Santo, Anna E. Oja, J. Kühne, Willem van de Veen, Mary Bebawy, Alberto Mantovani, Bart Everts, Giovanna Lombardi, Laura Maggi, Anouk von Borstel, Pia Kvistborg, Elisabetta Traggiai, A Ochel, Nima Aghaeepour, Charles-Antoine Dutertre, Matthieu Allez, Thomas Höllt, Wenjun Ouyang, Regina Stark, Maries van den Broek, Shimon Sakaguchi, Paul K. Wallace, Silvano Sozzani, Francesca LaRosa, Annette Oxenius, Malgorzata J. Podolska, Ivana Marventano, Wilhelm Gerner, Oliver F. Wirz, Britta Frehse, Gevitha Ravichandran, Martin Herrmann, Carl S. Goodyear, Gary Warnes, Helen Ferry, Stefan Frischbutter, Tim R. Radstake, Salomé LeibundGut-Landmann, Yi Zhao, Axel Schulz, Angela Santoni, Pablo Engel, Daniela C. Hernández, Andreas Acs, Cristiano Scottà, Francesco Annunziato, Thomas Weisenburger, Wolfgang Beisker, Sue Chow, Fritz Melchers, Daniel E. Speiser, Immanuel Kwok, Florent Ginhoux, Dominic A. Boardman, Natalie Stanley, Carsten Watzl, Marie Follo, Erik Lubberts, Andreas Krueger, Susanne Ziegler, Göran K. Hansson, David Voehringer, Antonia Niedobitek, Eleni Christakou, Lai Guan Ng, Sabine Baumgart, Nicholas A Gherardin, Antonio Cosma, Orla Maguire, Jolene Bradford, Daniel Schraivogel, Linda Quatrini, Stephen D. Miller

Publikováno v: European Journal of Immunology, 49(10), 1457-1973. Wiley-VCH
European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2019, 49 (10), pp.1457-1973. ⟨10.1002/eji.201970107⟩
European Journal of Immunology, 2019, 49 (10), pp.1457-1973. ⟨10.1002/eji.201970107⟩
Eur J Immunol
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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European journal of immunology
European journal of immunology, Vol. 49, no.10, p. 1457-1973 (2019)
EUROPEAN JOURNAL OF IMMUNOLOGY
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Digital.CSIC. Repositorio Institucional del CSIC
Volume 49
Issue 10
European journal of immunology, 49(10), 1457-1973. Wiley-VCH Verlag
European Journal of Immunology, 49(10), 1457-1973
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
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Cossarizza, A, Chang, H-D, Radbruch, A, Acs, A, Adam, D, Adam-Klages, S, Agace, W W, Aghaeepour, N, Akdis, M, Allez, M, Almeida, L N, Alvisi, G, Anderson, G, Andrä, I, Annunziato, F, Anselmo, A, Bacher, P, Baldari, C T, Bari, S, Barnaba, V, Barros-Martins, J, Battistini, L, Bauer, W, Baumgart, S, Baumgarth, N, Baumjohann, D, Baying, B, Bebawy, M, Becher, B, Beisker, W, Benes, V, Beyaert, R, Blanco, A, Boardman, D A, Bogdan, C, Borger, J G, Borsellino, G, Boulais, P E, Bradford, J A, Brenner, D, Brinkman, R R, Brooks, A E S, Busch, D H, Büscher, M, Bushnell, T P, Calzetti, F, Cameron, G, Cammarata, I, Cao, X, Cardell, S L, Casola, S, Cassatella, M A, Cavani, A, Celada, A, Chatenoud, L, Chattopadhyay, P K, Chow, S, Christakou, E, Čičin-Šain, L, Clerici, M, Colombo, F S, Cook, L, Cooke, A, Cooper, A M, Corbett, A J, Cosma, A, Cosmi, L, Coulie, P G, Cumano, A, Cvetkovic, L, Dang, V D, Dang-Heine, C, Davey, M S, Davies, D, De Biasi, S, Del Zotto, G, Dela Cruz, G V, Delacher, M, Della Bella, S, Dellabona, P, Deniz, G, Dessing, M, Di Santo, J P, Diefenbach, A, Dieli, F, Dolf, A, Dörner, T, Dress, R J, Dudziak, D, Dustin, M, Dutertre, C-A, Ebner, F, Eckle, S B G, Edinger, M, Eede, P, Ehrhardt, G R A, Eich, M, Engel, P, Engelhardt, B, Erdei, A, Esser, C, Everts, B, Evrard, M, Falk, C S, Fehniger, T A, Felipo-Benavent, M, Ferry, H, Feuerer, M, Filby, A, Filkor, K, Fillatreau, S, Follo, M, Förster, I, Foster, J, Foulds, G A, Frehse, B, Frenette, P S, Frischbutter, S, Fritzsche, W, Galbraith, D W, Gangaev, A, Garbi, N, Gaudilliere, B, Gazzinelli, R T, Geginat, J, Gerner, W, Gherardin, N A, Ghoreschi, K, Gibellini, L, Ginhoux, F, Goda, K, Godfrey, D I, Goettlinger, C, González-Navajas, J M, Goodyear, C S, Gori, A, Grogan, J L, Grummitt, D, Grützkau, A, Haftmann, C, Hahn, J, Hammad, H, Hämmerling, G, Hansmann, L, Hansson, G, Harpur, C M, Hartmann, S, Hauser, A, Hauser, A E, Haviland, D L, Hedley, D, Hernández, D C, Herrera, G, Herrmann, M, Hess, C, Höfer, T, Hoffmann, P, Hogquist, K, Holland, T, Höllt, T, Holmdahl, R, Hombrink, P, Houston, J P, Hoyer, B F, Huang, B, Huang, F-P, Huber, J E, Huehn, J, Hundemer, M, Hunter, C A, Hwang, W Y K, Iannone, A, Ingelfinger, F, Ivison, S M, Jäck, H-M, Jani, P K, Jávega, B, Jonjic, S, Kaiser, T, Kalina, T, Kamradt, T, Kaufmann, S H E, Keller, B, Ketelaars, S L C, Khalilnezhad, A, Khan, S, Kisielow, J, Klenerman, P, Knopf, J, Koay, H-F, Kobow, K, Kolls, J K, Kong, W T, Kopf, M, Korn, T, Kriegsmann, K, Kristyanto, H, Kroneis, T, Krueger, A, Kühne, J, Kukat, C, Kunkel, D, Kunze-Schumacher, H, Kurosaki, T, Kurts, C, Kvistborg, P, Kwok, I, Landry, J, Lantz, O, Lanuti, P, LaRosa, F, Lehuen, A, LeibundGut-Landmann, S, Leipold, M D, Leung, L Y T, Levings, M K, Lino, A C, Liotta, F, Litwin, V, Liu, Y, Ljunggren, H-G, Lohoff, M, Lombardi, G, Lopez, L, López-Botet, M, Lovett-Racke, A E, Lubberts, E, Luche, H, Ludewig, B, Lugli, E, Lunemann, S, Maecker, H T, Maggi, L, Maguire, O, Mair, F, Mair, K H, Mantovani, A, Manz, R A, Marshall, A J, Martínez-Romero, A, Martrus, G, Marventano, I, Maslinski, W, Matarese, G, Mattioli, A V, Maueröder, C, Mazzoni, A, McCluskey, J, McGrath, M, McGuire, H M, McInnes, I B, Mei, H E, Melchers, F, Melzer, S, Mielenz, D, Miller, S D, Mills, K H G, Minderman, H, Mjösberg, J, Moore, J, Moran, B, Moretta, L, Mosmann, T R, Müller, S, Multhoff, G, Muñoz, L E, Münz, C, Nakayama, T, Nasi, M, Neumann, K, Ng, L G, Niedobitek, A, Nourshargh, S, Núñez, G, O'Connor, J-E, Ochel, A, Oja, A, Ordonez, D, Orfao, A, Orlowski-Oliver, E, Ouyang, W, Oxenius, A, Palankar, R, Panse, I, Pattanapanyasat, K, Paulsen, M, Pavlinic, D, Penter, L, Peterson, P, Peth, C, Petriz, J, Piancone, F, Pickl, W F, Piconese, S, Pinti, M, Pockley, A G, Podolska, M J, Poon, Z, Pracht, K, Prinz, I, Pucillo, C E M, Quataert, S A, Quatrini, L, Quinn, K M, Radbruch, H, Radstake, T R D J, Rahmig, S, Rahn, H-P, Rajwa, B, Ravichandran, G, Raz, Y, Rebhahn, J A, Recktenwald, D, Reimer, D, Reis E Sousa, C, Remmerswaal, E B M, Richter, L, Rico, L G, Riddell, A, Rieger, A M, Robinson, J P, Romagnani, C, Rubartelli, A, Ruland, J, Saalmüller, A, Saeys, Y, Saito, T, Sakaguchi, S, Sala-de-Oyanguren, F, Samstag, Y, Sanderson, S, Sandrock, I, Santoni, A, Sanz, R B, Saresella, M, Sautes-Fridman, C, Sawitzki, B, Schadt, L, Scheffold, A, Scherer, H U, Schiemann, M, Schildberg, F A, Schimisky, E, Schlitzer, A, Schlosser, J, Schmid, S, Schmitt, S, Schober, K, Schraivogel, D, Schuh, W, Schüler, T, Schulte, R, Schulz, A R, Schulz, S R, Scottá, C, Scott-Algara, D, Sester, D P, Shankey, T V, Silva-Santos, B, Simon, A K, Sitnik, K M, Sozzani, S, Speiser, D E, Spidlen, J, Stahlberg, A, Stall, A M, Stanley, N, Stark, R, Stehle, C, Steinmetz, T, Stockinger, H, Takahama, Y, Takeda, K, Tan, L, Tárnok, A, Tiegs, G, Toldi, G, Tornack, J, Traggiai, E, Trebak, M, Tree, T I M, Trotter, J, Trowsdale, J, Tsoumakidou, M, Ulrich, H, Urbanczyk, S, van de Veen, W, van den Broek, M, van der Pol, E, Van Gassen, S, Van Isterdael, G, van Lier, R A W, Veldhoen, M, Vento-Asturias, S, Vieira, P, Voehringer, D, Volk, H-D, von Borstel, A, von Volkmann, K, Waisman, A, Walker, R V, Wallace, P K, Wang, S A, Wang, X M, Ward, M D, Ward-Hartstonge, K A, Warnatz, K, Warnes, G, Warth, S, Waskow, C, Watson, J V, Watzl, C, Wegener, L, Weisenburger, T, Wiedemann, A, Wienands, J, Wilharm, A, Wilkinson, R J, Willimsky, G, Wing, J B, Winkelmann, R, Winkler, T H, Wirz, O F, Wong, A, Wurst, P, Yang, J H M, Yang, J, Yazdanbakhsh, M, Yu, L, Yue, A, Zhang, H, Zhao, Y, Ziegler, S M, Zielinski, C, Zimmermann, J & Zychlinsky, A 2019, ' Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) ', European Journal of Immunology, vol. 49, no. 10, pp. 1457-1973 . https://doi.org/10.1002/eji.201970107

All authors: Andrea Cossarizza Hyun‐Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam‐Klages William W. Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Fra

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