Výsledky vyhledávání - "Christopher M Haqq"

Akademický článek

Gene expression and biological pathways in tissue of men with prostate cancer in a randomized clinical trial of lycopene and fish oil supplementation.

Autor: Mark Jesus M Magbanua, Ritu Roy, Eduardo V Sosa, Vivian Weinberg, Scott Federman, Michael D Mattie, Millie Hughes-Fulford, Jeff Simko, Katsuto Shinohara, Christopher M Haqq, Peter R Carroll, June M Chan

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24004 (2011)

Studies suggest that micronutrients may modify the risk or delay progression of prostate cancer; however, the molecular mechanisms involved are poorly understood. We examined the effects of lycopene and fish oil on prostate gene expression in a doubl

Externí odkaz: https://doaj.org/article/ec6dade537a44548b820e607a36c0505

Zobrazit plný text záznamu

Akademický článek

Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates

Autor: Lochana M. Seenappa, Aniela Jakubowski, Martin P. Steinbuck, Erica Palmer, Christopher M. Haqq, Crystal Carter, Jane Fontenot, Francois Villinger, Lisa K. McNeil, Peter C. DeMuth

Publikováno v: npj Vaccines, Vol 7, Iss 1, Pp 1-16 (2022)

Abstract Despite the success of currently authorized vaccines for the reduction of severe COVID-19 disease risk, rapidly emerging viral variants continue to drive pandemic waves of infection, resulting in numerous global public health challenges. Pro

Externí odkaz: https://doaj.org/article/0e0c165500e944c68281b4df4a9887a4

Zobrazit plný text záznamu

Data from First-in-Human Phase I Study of the Activin A Inhibitor, STM 434, in Patients with Granulosa Cell Ovarian Cancer and Other Advanced Solid Tumors

Autor: David M. Hyman, Christopher M. Haqq, Willis H. Navarro, Drew W. Rasco, Joyce F. Liu, Karen A. Cadoo, Vicky Makker, Nicholas A. Cangemi, Jessica J. Tao

Purpose:STM 434 is a soluble receptor ligand trap targeting activin A, a protein in the TGFβ family that plays important roles in growth, differentiation, and cancer cachexia. This study evaluated the safety, antitumor activity, and metabolic effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d0c219c5c6e710835150abcc51ec4d
https://doi.org/10.1158/1078-0432.c.6527765

Zobrazit plný text záznamu

Lymph node-targeted vaccine boosting of TCR-T cell therapy enhances anti-tumor function and eradicates solid tumors

Autor: Dylan J. Drakes, Abdulraouf M. Abbas, Jacqueline Shields, Martin P. Steinbuck, Aniela Jakubowski, Lochana M. Seenappa, Christopher M. Haqq, Peter C. DeMuth

While T cell receptor (TCR)-modified T cell therapies have shown promise against solid tumors, overall therapeutic benefits in clinical practice have been modest due in part to suboptimal T cell persistence and activation in vivo, alongside the possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c75470b10dcf0ff3789539378b3fae3d
https://doi.org/10.1101/2022.05.05.490779

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání