Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Christopher M Evans"'
Publikováno v:
Allergology International, Vol 73, Iss 3, Pp 375-381 (2024)
Mucus provides a protective barrier that is crucial for host defense in the lungs. However, excessive or abnormal mucus can have pathophysiological consequences in many pulmonary diseases, including asthma. Patients with asthma are treated with agent
Externí odkaz:
https://doaj.org/article/ecf785d2746346daa0eed1ee37bf80ba
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Materials with tunable modulus, viscosity, and complex viscoelastic spectra are crucial in applications such as self-healing, additive manufacturing, and energy damping. It is still challenging to predictively design polymer networks with hi
Externí odkaz:
https://doaj.org/article/d10de223e1be403aa44d7bd7a92c673d
Publikováno v:
Frontiers in Soft Matter, Vol 3 (2023)
The kinetics of crystallization and crystal-crystal transformations in ethylene vitrimers are studied by time-domain NMR. These vitrimers previously exhibited polymorphic transition of crystal structures, which are shown here to be distinguishable by
Externí odkaz:
https://doaj.org/article/60ef4ce5fa964e03b61f29f20e8d0f1c
Autor:
Jingcheng Ma, Laura E. Porath, Md Farhadul Haque, Soumyadip Sett, Kazi Fazle Rabbi, SungWoo Nam, Nenad Miljkovic, Christopher M. Evans
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
By now a plethora of ultrathin hydrophobic coatings are available but their durability are not well developed. Here, the authors present a thin, durable and fluorine-free PDMS-based vitrimer coating that implements many desirable aspects like energy
Externí odkaz:
https://doaj.org/article/b8f36c41b20146018b4d25a2f09df596
Autor:
Leslie E. Morgan, Ana M. Jaramillo, Siddharth K. Shenoy, Dorota Raclawska, Nkechinyere A. Emezienna, Vanessa L. Richardson, Naoko Hara, Anna Q. Harder, James C. NeeDell, Corinne E. Hennessy, Hassan M. El-Batal, Chelsea M. Magin, Diane E. Grove Villalon, Gregg Duncan, Justin S. Hanes, Jung Soo Suk, David J. Thornton, Fernando Holguin, William J. Janssen, William R. Thelin, Christopher M. Evans
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
In asthma, mucus plugging is an important cause of airflow obstruction, but it is not targeted by widely used bronchodilator and anti-inflammatory drugs. Here the authors show that reduction of disulfide bonds that hold mucin polymers together revers
Externí odkaz:
https://doaj.org/article/2fb68d67a4a24797aac17403bb6726b1
Autor:
Aran Singanayagam, Joseph Footitt, Matthias Marczynski, Giorgia Radicioni, Michael T. Cross, Lydia J. Finney, Maria-Belen Trujillo-Torralbo, Maria Calderazzo, Jie Zhu, Julia Aniscenko, Thomas B. Clarke, Philip L. Molyneaux, Nathan W. Bartlett, Miriam F. Moffatt, William O. Cookson, Jadwiga Wedzicha, Christopher M. Evans, Richard C. Boucher, Mehmet Kesimer, Oliver Lieleg, Patrick Mallia, Sebastian L. Johnston
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
The respiratory tract surface is protected from inhaled pathogens by a secreted layer of mucus rich in mucin glycoproteins. Abnormal mucus accumulation is a cardinal feature of chronic respiratory diseases, but the relationship between mucus and path
Externí odkaz:
https://doaj.org/article/8bada2e2d7bf4317a4dc8b248c77d273
Autor:
Laura A. Hancock, Corinne E. Hennessy, George M. Solomon, Evgenia Dobrinskikh, Alani Estrella, Naoko Hara, David B. Hill, William J. Kissner, Matthew R. Markovetz, Diane E. Grove Villalon, Matthew E. Voss, Guillermo J. Tearney, Kate S. Carroll, Yunlong Shi, Marvin I. Schwarz, William R. Thelin, Steven M. Rowe, Ivana V. Yang, Christopher M. Evans, David A. Schwartz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The promoter variant rs35705950 confers a gain of function to the MUC5B gene and is the dominant risk factor for idiopathic pulmonary fibrosis. Here the authors show that mice overexpressing Muc5b in distal airspaces show impaired mucociliary clearan
Externí odkaz:
https://doaj.org/article/179e7c61d4b74fa68c0ec80470732ff6
Publikováno v:
Macromolecules. 56:3383-3392
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e387f3a8c7c9dbee2bed4a037080b1
https://doi.org/10.1021/acs.macromol.2c02388
https://doi.org/10.1021/acs.macromol.2c02388
Autor:
Tsukasa, Okamoto, Evgenia, Dobrinskikh, Corinne E, Hennessy, Naoko, Liu, Marvin I, Schwarz, Christopher M, Evans, Andrew P, Fontenot, Ivana V, Yang, David A, Schwartz
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(3)
Previously we have shown that a gain-of-function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7fe4d702be119352b7b0da1d8467897
https://pubmed.ncbi.nlm.nih.gov/35881171
https://pubmed.ncbi.nlm.nih.gov/35881171
Autor:
Baicheng Mei, Tsai-Wei Lin, Grant S. Sheridan, Christopher M. Evans, Charles E. Sing, Kenneth S. Schweizer
Publikováno v:
ACS Central Science. 9:508-518
The diffusion of molecules (penetrants) of variable size, shape, and chemistry through dense crosslinked polymer networks is a fundamental scientific problem that is broadly relevant in materials, polymer, physical and biological chemistry. Relevant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1307455cfa1e92db73dcbbc999f283
https://doi.org/10.1021/acscentsci.2c01373
https://doi.org/10.1021/acscentsci.2c01373