Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Christopher M, Weghorst"'
Publikováno v:
Toxins, Vol 14, Iss 7, p 484 (2022)
Exposure to cyanobacterial hepatotoxins has been linked to the promotion and increased incidence of liver cancer in pre-clinical and epidemiologic studies. The family of hepatotoxins, microcystins (MCs), are produced by over 40 cyanobacterial species
Externí odkaz:
https://doaj.org/article/85b6a12d596d480cb6bd707492a2a120
Autor:
Pengcheng Tu, Xiaoming Bian, Liang Chi, Bei Gao, Hongyu Ru, Thomas J. Knobloch, Christopher M. Weghorst, Kun Lu
Publikováno v:
ACS Omega, Vol 3, Iss 9, Pp 10927-10937 (2018)
Externí odkaz:
https://doaj.org/article/5ac764abdba3489d93f6b22f77088120
Autor:
Steve Oghumu, Bruce C. Casto, Jennifer Ahn-Jarvis, Logan C. Weghorst, Jim Maloney, Paul Geuy, Kyle Z. Horvath, Claire E. Bollinger, Blake M. Warner, Kurt F. Summersgill, Christopher M. Weghorst, Thomas J. Knobloch
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Oral cancer continues to be a significant public health problem worldwide. Recently conducted clinical trials demonstrate the ability of black raspberries (BRBs) to modulate biomarkers of molecular efficacy that supports a chemopreventive strategy ag
Externí odkaz:
https://doaj.org/article/9f5d33ee7daa44768045473022bfd3af
Autor:
Thomas J. Knobloch, Nathan M. Ryan, Lei Bruschweiler-Li, Cheng Wang, Matthew C. Bernier, Arpad Somogyi, Pearlly S. Yan, Jessica L. Cooperstone, Xiaokui Mo, Rafael P. Brüschweiler, Christopher M. Weghorst, Steve Oghumu
Publikováno v:
Metabolites, Vol 9, Iss 7, p 140 (2019)
Oral cancer is a public health problem with an incidence of almost 50,000 and a mortality of 10,000 each year in the USA alone. Black raspberries (BRBs) have been shown to inhibit oral carcinogenesis in several preclinical models, but our understandi
Externí odkaz:
https://doaj.org/article/35084e402d3c4843a44f232111d3f4cf
Publikováno v:
International Journal of Nanomedicine. 15:8217-8230
Purpose Black raspberries (BRBs) and their anthocyanin-rich hydrophilic fractions (BRB-H) have exhibited significant chemopreventative activity across aerodigestive cancers. Lutein, the primary component of the BRB lipophilic fraction (BRB-L), also d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7667ae86aaa0ef54daff3e7b90f06640
https://doi.org/10.2147/ijn.s259202
https://doi.org/10.2147/ijn.s259202
Autor:
Igor Mrdjen, Mark A. Morse, Randall J. Ruch, Thomas J. Knobloch, Shambhunath Choudhary, Christopher M. Weghorst, Jiyoung Lee
Publikováno v:
Toxins, Vol 10, Iss 11, p 435 (2018)
Microcystin (MC) exposure is an increasing concern because more geographical locations are covered with cyanobacterial blooms as eutrophication and bloom-favoring environmental factors become more prevalent worldwide. Acute MC exposure has been linke
Externí odkaz:
https://doaj.org/article/cf02d4806c344cc4834072c5011ad7af
Autor:
Yi Guo, Michael L. Pennell, Dennis K. Pearl, Thomas J. Knobloch, Soledad Fernandez, Christopher M. Weghorst
Publikováno v:
BioTechniques, Vol 55, Iss 4, Pp 207-209 (2013)
Quantitative polymerase chain reaction (qPCR), a highly sensitive method of measuring gene expression, is widely used in biomedical research. To produce reliable results, it is essential to use stably expressed reference genes (RGs) for data normaliz
Externí odkaz:
https://doaj.org/article/40051d6ab042423e9f07dbb5c24a8f90
Autor:
Marta T. Sears, Michael A. Schiano, Steve Oghumu, Erinn M. Hade, Electra D. Paskett, David E. Cohn, Jamie L. Lesnock, Logan C. Weghorst, Zhaoxia Zhang, Jondavid Pollock, Erin Strawser, Thomas J. Knobloch, William C. McBee, Mack T. Ruffin, Byron C. Calhoun, Cecilia R. DeGraffinreid, Holly H. Gallion, Blessing E. Ogbemudia, Joseph T. Perrault, Juan Peng, Christopher M. Weghorst, Bo Lu
Publikováno v:
Cancer Causes Control
PURPOSE: This study examined targeted genomic variants of transforming growth factor beta (TGFB) signaling in Appalachian women. Appalachian women with cervical cancer were compared to healthy Appalachian counterparts to determine whether these polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3693ef1a7cedc0fd8350af4572b991bf
https://doi.org/10.1007/s10552-019-01221-y
https://doi.org/10.1007/s10552-019-01221-y
Autor:
Steven J. Hughes, Mark A. Morse, Christopher M. Weghorst, Hyesook Kim, Paul B. Watkins, F. Peter Guengerich, Mark B. Orringer, David G. Beer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 2, Pp 145-153 (1999)
The expression of cytochromes P450 (CYP) in Barrett's esophagus and esophageal squamous mucosa was investigated. Esophagectomy specimens from 23 patients were examined for CYP expression of CYP1A2, CYP3A4, CYP2C9/10, and CYP2E1 by immunohistochemical
Externí odkaz:
https://doaj.org/article/296a291f73cd492bb63c437c02ed9e74
Publikováno v:
BioTechniques, Vol 22, Iss 4, Pp 608-612 (1997)
Externí odkaz:
https://doaj.org/article/74aa8768e35a460dada7453c3cabd2a9