Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christopher M, Mazzone"'
Autor:
Natale R. Sciolino, Madeline Hsiang, Christopher M. Mazzone, Leslie R. Wilson, Nicholas W. Plummer, Jaisal Amin, Kathleen G. Smith, Christopher A. McGee, Sydney A. Fry, Cindy X. Yang, Jeanne M. Powell, Michael R. Bruchas, Alexxai V. Kravitz, Jesse D. Cushman, Michael J. Krashes, Guohong Cui, Patricia Jensen
Publikováno v:
Science Advances. 8
Recent data demonstrate that noradrenergic neurons of the locus coeruleus (LC-NE) are required for fear-induced suppression of feeding, but the role of endogenous LC-NE activity in natural, homeostatic feeding remains unclear. Here, we found that LC-
Serotonin Modulates an Inhibitory Input to the Central Amygdala from the Ventral Periaqueductal Gray
Autor:
Olivia J. Hon, Jeffrey F. DiBerto, Christopher M. Mazzone, Jonathan Sugam, Daniel W. Bloodgood, J. Andrew Hardaway, Mariya Husain, Alexis Kendra, Nora M. McCall, Alberto J. Lopez, Thomas L. Kash, Emily G. Lowery-Gionta
Fear is an adaptive state that drives defensive behavioral responses to specific and imminent threats. The central nucleus of the amygdala (CeA) is a critical site of adaptations that are required for the acquisition and expression of fear, in part d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0a8baa407b324689d57d32ff9be7a2
https://doi.org/10.1101/2022.03.28.486055
https://doi.org/10.1101/2022.03.28.486055
Serotonin modulates an inhibitory input to the central amygdala from the ventral periaqueductal gray
Autor:
Olivia J, Hon, Jeffrey F, DiBerto, Christopher M, Mazzone, Jonathan, Sugam, Daniel W, Bloodgood, J Andrew, Hardaway, Mariya, Husain, Alexis, Kendra, Nora M, McCall, Alberto J, Lopez, Thomas L, Kash, Emily G, Lowery-Gionta
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(13)
Fear is an adaptive state that drives defensive behavioral responses to specific and imminent threats. The central nucleus of the amygdala (CeA) is a critical site of adaptations that are required for the acquisition and expression of fear, in part d
Autor:
Yulong Li, Christopher M. Mazzone, Deepa M Reddy, Montana H. Boone, Fangmiao Sun, Morgan Southern, Yajun Zhang, Isabel de Araujo Salgado, Jing Liang-Guallpa, Chia Li, Michael J. Krashes, Nora S Wolcott, Nicholas P Kobzar, Guohong Cui
Publikováno v:
Nature neuroscience
Summary Maintaining healthy body weight is increasingly difficult in our obesogenic environment. Dieting efforts are often overpowered by the internal drive to consume energy-dense foods. While the selection of calorically-rich substrates over health
Autor:
Natale R. Sciolino, Madeline Hsiang, Christopher M. Mazzone, Leslie R. Wilson, Nicholas W. Plummer, Jaisal Amin, Kathleen G. Smith, Christopher A. McGee, Sydney A. Fry, Cindy X. Yang, Jeanne M. Powell, Michael R. Bruchas, Alexxai V. Kravitz, Jesse D. Cushman, Michael J. Krashes, Guohong Cui, Patricia Jensen
Recent data suggest that LC-NE neurons play a role in fear-induced suppression of feeding, but their endogenous activity in naturally behaving animals has not been explored. We found that endogenous activity of LC-NE neurons was enhanced during food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873e7b79908ef3118f43d01214a6a5cc
Autor:
Christopher M. Mazzone, Kristen E. Pleil, Varun Gulati, Emily G. Lowery-Gionta, Montserrat Navarro, Thomas L. Kash, Jennifer A. Rinker, Todd E. Thiele, S. Alex Marshall
Publikováno v:
Biological Psychiatry. 81:930-940
Background Corticotropin-releasing factor (CRF) signaling at the CRF 1 receptor (CRF 1 R) in the ventral tegmental area (VTA) can modulate ethanol consumption in rodents. However, the effects of binge-like ethanol drinking on this system have not bee
Autor:
Jessica M. McKlveen, K Duffy, James H. Fox, Sayamwong E. Hammack, Dipanwita Pati, Jeffrey F. DiBerto, Thomas L. Kash, S T Magness, Gregory J. Tipton, Christopher M. Mazzone, Yasmin L. Hurd, Zoe A. McElligott, William A. Falls, Michael Michaelides, C Anderson, J A Hardaway
Publikováno v:
Molecular Psychiatry. 23:143-153
The bed nucleus of the stria terminalis (BNST) is a brain region important for regulating anxiety-related behavior in both humans and rodents. Here we used a chemogenetic strategy to investigate how engagement of G protein-coupled receptor (GPCR) sig
Autor:
Michelle J. Kim, J. Andrew Hardaway, Dipanwita Pati, Kristen M. Boyt, Christopher M. Mazzone, Andrew Holmes, Daniel W. Bloodgood, Michael P. Saddoris, Olivia J Hon, Cynthia M. Bulik, Garret D. Stuber, Michael R. Bruchas, Thomas L. Kash, Jennifer R. Jensen, Greg Tipton, Christina M. Stanhope, Sofia Neira, Thomas C. Jhou, Ava Erfani, Zoe A. McElligott, Ami Shiddapur, Jonathan A. Sugam, Jeffrey F. DiBerto, Lindsay R. Halladay
Publikováno v:
Neuron
Summary Food palatability is one of many factors that drives food consumption, and the hedonic drive to feed is a key contributor to obesity and binge eating. In this study, we identified a population of prepronociceptin-expressing cells in the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec4b76444449644e580c8fe963fa995
Publikováno v:
Brain structurefunction. 223(8)
Emotional behavioral responses related to anxiety and fear comprise the negative valence systems domain as defined by the Research Domain Criteria (RDoC) approach to categorizing related emotional behavioral constructs that are compromised in mental
Autor:
David P. Olson, Thomas L. Kash, Alexis M. Kendra, Jennifer A. Rinker, Bradford B. Lowell, Kristen E. Pleil, Emily G. Lowery-Gionta, Nora M. McCall, Todd E. Thiele, Kathleen A. Grant, Christopher M. Mazzone
Publikováno v:
Nature neuroscience
Summary paragraph Binge alcohol drinking is a tremendous public health problem because it leads to the development of numerous pathologies including alcohol abuse, and anxiety1–4. It is thought to do so by hijacking brain systems that regulate stre