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pro vyhledávání: '"Christopher Loewen"'
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Advances in sequencing technology have led to an explosion in the number of known genetic variants of human genes. A major challenge is to now determine which of these variants contribute to diseases as a result of their effect on gene function. Here
Externí odkaz:
https://doaj.org/article/0d7eed35730249099d13592cfce5a521
Autor:
Krystina L Ho, Lina Ma, Stephanie Cheung, Savrina Manhas, Nancy Fang, Kaiqian Wang, Barry Young, Christopher Loewen, Thibault Mayor, Vivien Measday
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005109 (2015)
Separase/Esp1 is a protease required at the onset of anaphase to cleave cohesin and thereby enable sister chromatid separation. Esp1 also promotes release of the Cdc14 phosphatase from the nucleolus to enable mitotic exit. To uncover other potential
Externí odkaz:
https://doaj.org/article/50eeefba8d2e4812857dd71182784c8d