Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher Liczner"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 908-931 (2021)
Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to t
Externí odkaz:
https://doaj.org/article/48482f334881480e8d600f8d47f6f6c8
Publikováno v:
Chemical Science. 13:410-420
A breadth of strategies are needed to efficiently modify oligonucleotides with peptides or lipids to capitalize on their therapeutic and diagnostic potential, including the modulation of in vivo chemical stability and for applications in cell-targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea562335eebcae1ecca6fcf5da67c13b
https://doi.org/10.1039/d1sc04937b
https://doi.org/10.1039/d1sc04937b
Autor:
Kieran Duke, Gabrielle A. Mandl, Christopher Liczner, John A. Capobianco, Christopher J. Wilds, Steven L. Maurizio
Publikováno v:
Materials Chemistry Frontiers. 5:4690-4699
Photo-mediated systems present a highly attractive route for controlling the intracellular delivery of their cargo. Of particular interest, oligonucleotides are a promising class of molecule that are highly versatile for intracellular applications, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff7ec0ffbc00fb1e3ae285d85be898b
https://doi.org/10.1039/d1qm00467k
https://doi.org/10.1039/d1qm00467k
Publikováno v:
Chemical Science
A breadth of strategies are needed to efficiently modify oligonucleotides with peptides or lipids to capitalize on their therapeutic and diagnostic potential, including the modulation of in vivo chemical stability and for applications in cell-targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::465a11346745e1c6cf56eb3f53b73ae8
https://pubmed.ncbi.nlm.nih.gov/35126973
https://pubmed.ncbi.nlm.nih.gov/35126973
Publikováno v:
Tetrahedron Letters. 59:38-41
We have synthesized and characterized a phosphoramidite derivative of 2’-deoxy-6-selenoinosine (d6SeI) and incorporated this modification into an oligonucleotide by solid-phase synthesis. During cleavage from the solid-support and deprotection, spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3dfabb3df26f53d87f7120a1836d74d
https://doi.org/10.1016/j.tetlet.2017.11.044
https://doi.org/10.1016/j.tetlet.2017.11.044
Autor:
Nozhat Safaee, Anne M. Noronha, Christopher Liczner, Kalle Gehring, William Copp, J. Xie, Christopher J. Wilds, Alexey Yu. Denisov
Publikováno v:
Nucleic Acids Research
Polyadenylate (poly(A)) has the ability to form a parallel duplex with Hoogsteen adenine:adenine base pairs at low pH or in the presence of ammonium ions. In order to evaluate the potential of this structural motif for nucleic acid-based nanodevices,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4aead204882d26678a9054fcb80c16
http://europepmc.org/articles/PMC5737284
http://europepmc.org/articles/PMC5737284