Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christopher L. Sorge"'
Autor:
Peter M. Grob, Janice R. Brickwood, Cheng-Kon Shih, Maryann Hoermann, Julian Adams, Racheline Schwartz, Daniel Pauletti, Eva David, David A. Erickson, Kevin Barringer, Charles L. Cywin, David Joseph, Susan E. Hattox, Janice M. Klunder, Christopher L. Sorge
Publikováno v:
Journal of Medicinal Chemistry. 41:2960-2971
Like other nonnucleoside inhibitors of HIV-1 reverse transcriptase, the dipyridodiazepinone nevirapine (Viramune, 1) selects for drug resistant variants of HIV-1, both in cell culture and in patients. In particular, the mutation of residue 181 from t
Autor:
George B. Corcoran, Judy L. Raucy, Sidhartha D. Ray, Christopher L. Sorge, Asadollah Tavacoli
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468458794
Much attention has fallen upon Ca2+ and the critical role it appears to play in the process of lethal cell injury (Schanne et al., 1979; Moore, 1980; Jewell et al., 1982). Ca2+ appears to serve as the principal intracellular messenger that conveys in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a18a7dab3b10e9ca7c795e0852a6f4e3
https://doi.org/10.1007/978-1-4684-5877-0_90
https://doi.org/10.1007/978-1-4684-5877-0_90
Publikováno v:
Biochemical and biophysical research communications. 157(1)
The obese overfed rat effectively models many of the pharmacological changes in human obesity. Recent data show that the obese rat is unusually susceptible to liver damage by several metabolically activated drugs that may be more toxic in obese human