Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christopher L. Sansam"'
Autor:
Maulin M. Patel, Amanda R. Behar, Robert Silasi, Girija Regmi, Christopher L. Sansam, Ravi S. Keshari, Florea Lupu, Cristina Lupu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 22 (2018)
Background The physiological function of ADTRP (androgen‐dependent tissue factor pathway inhibitor regulating protein) is unknown. We previously identified ADTRP as coregulating with and supporting the anticoagulant activity of tissue factor pathwa
Externí odkaz:
https://doaj.org/article/d9c6d72becd448488f6b53dd5124b376
Autor:
Emily A. Masser, Tyler D. Noble, Joseph C. Siefert, Duane Goins, Courtney G. Sansam, Christopher L. Sansam
Deregulated DNA replication causes human developmental disorders and cancer, but we know little about how DNA replication is coordinated with changes in transcription and chromatin structure. The initiation of replication forks follows a spatiotempor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752060fdae14d326319a30632943a2db
https://doi.org/10.1101/2022.10.21.512903
https://doi.org/10.1101/2022.10.21.512903
Publikováno v:
Genes; Volume 13; Issue 7; Pages: 1157
Induced pluripotent stem cells (iPSCs) hold great potential for regenerative medicine. By reprogramming a patient′s own cells, immunological rejection can be avoided during transplantation. For expansion and gene editing, iPSCs are grown in artific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bddc2503bb7d3fe1e43d877c2ae2a1
https://pubmed.ncbi.nlm.nih.gov/35885940
https://pubmed.ncbi.nlm.nih.gov/35885940
Publikováno v:
Nucleic Acids Research
A DNA replication program, which ensures that the genome is accurately and wholly replicated, is established during G1, before the onset of S phase. In G1, replication origins are licensed, and upon S phase entry, a subset of these will form active r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cee96092858cafb3c46b83b87fe37e0
https://pubmed.ncbi.nlm.nih.gov/34534348
https://pubmed.ncbi.nlm.nih.gov/34534348
Autor:
Clay A. Foster, Megan Malone-Perez, Arpan A. Sinha, Courtney G. Sansam, John Kimble Frazer, Pilar I. Andrade, Katie Foster, Christopher L. Sansam
Publikováno v:
Blood. 138:3315-3315
MYC is over-expressed by many cancers, yet its oncogenic mechanisms are incompletely understood. MYC is central to acute lymphoblastic leukemia (ALL) - the most common and second most lethal pediatric malignancy, and ALL afflicts even more adults. Mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0630b7dca434d16835f9189e97396a
https://doi.org/10.1182/blood-2021-153406
https://doi.org/10.1182/blood-2021-153406
Autor:
Eulália M. L. da Silva, Katarzyna M. Piekarz, Courtney G. Sansam, Susannah Rankin, Katherine McDonald, Jingrong Chen, Christopher L. Sansam, Reem M. Alomer
Publikováno v:
Proceedings of the National Academy of Sciences. 114:9906-9911
Sister chromatids are tethered together by the cohesin complex from the time they are made until their separation at anaphase. The ability of cohesin to tether sister chromatids together depends on acetylation of its Smc3 subunit by members of the Ec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5b24939cc072719e53ddc9ac82faa9
https://doi.org/10.1073/pnas.1708291114
https://doi.org/10.1073/pnas.1708291114
Publikováno v:
Genome Biology and Evolution
The DNA replication timing program is modulated throughout development and is also one of the main factors influencing the distribution of mutation rates across the genome. However, the relationship between the mutagenic influence of replication timi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef740ed617b9256d3d68b0bad9db2a8
https://pubmed.ncbi.nlm.nih.gov/31076752
https://pubmed.ncbi.nlm.nih.gov/31076752
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 178:8-15
The cell cycle is integrated with many aspects of embryonic development. Not only is proper control over the pace of cell proliferation important, but also the timing of cell cycle progression is coordinated with transcription, cell migration, and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ad3f4b7ab06f1fa6fca4b2c55919af
https://doi.org/10.1016/j.cbpc.2015.10.003
https://doi.org/10.1016/j.cbpc.2015.10.003
Autor:
Megan Malone-Perez, Christopher L. Sansam, Courtney G. Sansam, Arpan A. Sinha, J. Kimble Frazer, Pilar I. Andrade
Publikováno v:
Blood. 136:2-2
MYCis a key oncogene overexpressed by many cancers, however, its oncogenic mechanisms are poorly understood. MYC is also central to acute lymphoblastic leukemia (ALL), the most common and second most lethal pediatric malignancy. Much of MYC's oncogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dc0037f35b9cdfb74b268aa61592314
https://doi.org/10.1182/blood-2020-142890
https://doi.org/10.1182/blood-2020-142890
Autor:
Christopher L. Sansam, Robert Silasi, Girija Regmi, Amanda R. Behar, Cristina Lupu, Maulin M. Patel, Florea Lupu, Ravi S. Keshari
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The physiological function of ADTRP (androgen‐dependent tissue factor pathway inhibitor regulating protein) is unknown. We previously identified ADTRP as coregulating with and supporting the anticoagulant activity of tissue factor pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebdf5302cf9d71453ae072f856d9975
http://europepmc.org/articles/PMC6404433
http://europepmc.org/articles/PMC6404433