Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christopher L. Murriel"'
Autor:
Christopher L Murriel, Steven F. Dowdy
Publikováno v:
Expert Opinion on Drug Delivery. 3:739-746
As the plasma membrane and blood-brain barrier selectively restrict the entry of most compounds into cells to < 500 Da, delivering macromolecules into cells was, until recently, little more than a goal. However, with significant effort to capitalise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305c003380a326c4362b02a27ff4ca0d
https://doi.org/10.1517/17425247.3.6.739
https://doi.org/10.1517/17425247.3.6.739
Publikováno v:
Circulation Research. 97:78-85
Cardiac ischemia and reperfusion are associated with loss in the activity of the mitochondrial enzyme pyruvate dehydrogenase (PDH). Pharmacological stimulation of PDH activity improves recovery in contractile function during reperfusion. Signaling me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f76fc4ebdf31099b1b5e4c9499148f5
https://doi.org/10.1161/01.res.0000173896.32522.6e
https://doi.org/10.1161/01.res.0000173896.32522.6e
Autor:
Daria Mochly-Rosen, Eric N. Churchill, Koichi Inagaki, Luke I. Szweda, Christopher L. Murriel
Publikováno v:
Journal of Biological Chemistry. 279:47985-47991
Heart attacks caused by occlusion of coronary arteries are often treated by mechanical or enzymatic removal of the occlusion and reperfusion of the ischemic heart. It is now recognized that reperfusion per se contributes to myocardial damage, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0cc8adab57ce85b0c151c38add29d7
https://doi.org/10.1074/jbc.m405071200
https://doi.org/10.1074/jbc.m405071200
Publikováno v:
Archives of Biochemistry and Biophysics. 420:246-254
Heart attacks, or acute myocardial infarctions (AMI), affect more than one million people in the US every year. The damage that occurs to the heart by AMI is often permanent and as a result, the morbidity and mortality rates of patients that experien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742aa720f74c5f90758e7da44765efcd
https://doi.org/10.1016/j.abb.2003.08.038
https://doi.org/10.1016/j.abb.2003.08.038
Autor:
Christopher L, Murriel, Eric, Churchill, Koichi, Inagaki, Luke I, Szweda, Daria, Mochly-Rosen
Publikováno v:
The Journal of biological chemistry. 279(46)
Heart attacks caused by occlusion of coronary arteries are often treated by mechanical or enzymatic removal of the occlusion and reperfusion of the ischemic heart. It is now recognized that reperfusion per se contributes to myocardial damage, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e57def9581bba2e63fb6ca76910994ac
https://pubmed.ncbi.nlm.nih.gov/15339931
https://pubmed.ncbi.nlm.nih.gov/15339931
Autor:
Wenlin Yuan, Richard A.D. Carano, David Davis, Somasekar Seshagiri, Honglin Chen, Hani Bou-Reslan, Christopher L. Murriel, Denise M. Kenski, Leisa Johson, Yuxin Liang, Suzana S. Couto
Publikováno v:
Cancer Research. 70:LB-189
The Ras GTPase family controls numerous downstream signaling cascades in response to signals that regulate cellular processes including proliferation and survival. While Ras is one of the most prevalent targets for gain-of-function mutations in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e7a5b677163c136539409985cc0bd5
https://doi.org/10.1158/1538-7445.am10-lb-189
https://doi.org/10.1158/1538-7445.am10-lb-189
Autor:
Christopher L. Murriel, Denise Kenski, Wenlin Yuan, Honglin Chen, Georgia Hatzivassiliou, Klaus Hoeflich, Jeffrey Wallin, Marcia Belvin, Yuxin Liang, Somasekar Seshagiri, David P. Davis, Leisa Johnson
Publikováno v:
Cancer Research. 69:B31-B31
The Ras GTPase family controls numerous downstream signaling cascades in response to signals that regulate cellular processes including proliferation and survival. While Ras is one of the most prevalent targets for gain-of-function mutations in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0325879bd36422ad1ee91f53a087c8c1
https://doi.org/10.1158/0008-5472.fbcr09-b31
https://doi.org/10.1158/0008-5472.fbcr09-b31
Publikováno v:
Journal of Cardiac Failure. 9:S66
Background: Inhibiting δPKC translocation during ischemia and reperfusion protects the heart from cell death by affecting the progression of apoptosis. In the heart, δPKC is activated and translocates from the soluble to the particulate fraction du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6413a797b42fe37b600bd8997c604485
https://doi.org/10.1016/s1071-9164(03)00551-7
https://doi.org/10.1016/s1071-9164(03)00551-7