Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christopher L. Joannou"'
Publikováno v:
International Journal of Peptide Research and Therapeutics. 12:269-273
Microbes are increasingly developing defensive mechanisms against known drugs via mutations. There are signs of emergence of superbugs immune to most known antibiotics available. The need for a new class of drugs to counteract this problem is of para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24bceaa5082a99631aeec80eae23eace
https://doi.org/10.1007/s10989-006-9033-4
https://doi.org/10.1007/s10989-006-9033-4
Autor:
Giuliano Siligardi, Robert E. W. Hancock, Edward Odell, Robert W. Evans, Rohanah Hussain, Daniel S. Chapple, Christopher L. Joannou
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2190-2198
An 11-amino-acid amphipathic synthetic peptide homologous to a helical region on helix 1 of human lactoferrin HLP-2 exhibited bactericidal activity against Escherichia coli serotype O111, whereas an analogue synthesized with Pro substituted for Met,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125b197faff0361809560e9bddea0794
https://doi.org/10.1128/aac.48.6.2190-2198.2004
https://doi.org/10.1128/aac.48.6.2190-2198.2004
Autor:
Robert W. Evans, Henry K. Bayele, S. Kaila S. Srai, C.E. Naylor, Alpesh Patel, Nick Beaumont, Christopher L. Joannou, Basharut A. Syed, Peter S. N. Rowe
Publikováno v:
Protein Engineering, Design and Selection. 15:205-214
Hephaestin was implicated in mammalian iron homeostasis following its identification as the defective gene in murine sex-linked anaemia. It is a member of the family of copper oxidases that includes mammalian ceruloplasmin, factors V and VIII, yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe18408f60f9938089448a6c92f21f1
https://doi.org/10.1093/protein/15.3.205
https://doi.org/10.1093/protein/15.3.205
Autor:
Ian C. Boulton, Christopher L. Joannou, Beatrice Gorinsky, Mark D. Retzer, Anthony B. Schryvers, Robert W. Evans, Andrew Gorringe
Publikováno v:
Biochemical Journal. 339:143-149
Neisseria meningitidis, grown in iron-limited conditions, produces two transferrin-binding proteins (TbpA and TbpB) that independently and specifically bind human serum transferrin (hTF) but not bovine serum transferrin (bTF). We have used surface pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1f6db3bc532aa100da051964365a87b
https://doi.org/10.1042/bj3390143
https://doi.org/10.1042/bj3390143
Autor:
Claudia L. Torres Martinez, Ney V. Vugman, Nicola J. Rogers, Xiao-Yuan Cui, Martin N. Hughes, Christopher L. Joannou, Natasha Vielotte, Richard Cammack
Publikováno v:
Applied and Environmental Microbiology. 64:3195-3201
The potent bactericidal activity of sodium nitroprusside {SNP; Na 2 [Fe(CN) 5 (NO)]} towards Clostridium sporogenes has been investigated. SNP inhibited cell growth in the concentration range of 10 to 40 μM. Concentrations above 80 μM caused irreve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0b134641db1b6b9d6e70cc19ac924b
https://doi.org/10.1128/aem.64.9.3195-3201.1998
https://doi.org/10.1128/aem.64.9.3195-3201.1998
Publikováno v:
Infection and Immunity. 66:3591-3596
Staphylococcus aureus and Staphylococcus epidermidis both recognize and bind the human iron-transporting glycoprotein, transferrin, via a 42-kDa cell surface protein receptor. In an iron-deficient medium, staphylococcal growth can be promoted by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34362f865b474487f72863fef98f650f
https://doi.org/10.1128/iai.66.8.3591-3596.1998
https://doi.org/10.1128/iai.66.8.3591-3596.1998
Autor:
Kenneth N. White, Christine K. M. Suen, Natasha Choudhury, Mineza Rafiq, Christopher L. Joannou, Robert W. Evans
Publikováno v:
FEBS Letters. 407:132-136
We report the successful expression of recombinant human ceruloplasmin which was made possible by inclusion of splicing signals in the expression vector. Ceruloplasmin cDNA expressed from the vector pNUT in baby hamster kidney cells gave protein yiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cda1c5771d0c8b501a4ad2d3a4685e
https://doi.org/10.1016/s0014-5793(97)00325-6
https://doi.org/10.1016/s0014-5793(97)00325-6
Publikováno v:
Biochemistry. 34:16533-16542
One- and two-dimensional (1D and 2D) electron spin-echo envelope modulation (ESEEM) spectroscopy has been used to investigate the ligand environment of the [2Fe-2S] cluster from the terminal dioxygenase (ISPBED) of the Pseudomonas putida benzene diox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f01f234a759da324dbb03ec2459097
https://doi.org/10.1021/bi00051a001
https://doi.org/10.1021/bi00051a001
Publikováno v:
Pediatric Infectious Disease Journal. 22:284-286
Staphylococcal scalded skin syndrome is usually diagnosed clinically, and isolating Staphylococcus aureus from skin lesions is considered to support the diagnosis. However, polymerase chain reaction and Western blot analysis on 54 isolates from suspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5c45d9709e79781f2fd6b7bd9c4fbc8
https://doi.org/10.1097/01.inf.0000054023.19812.87
https://doi.org/10.1097/01.inf.0000054023.19812.87
Autor:
Russell H. Stokes, Jonathan S. Oakhill, Christopher L. Joannou, Andrew Gorringe, Robert W. Evans
Publikováno v:
Infection and immunity. 73(2)
Neisseria meningitidis , a causative agent of bacterial meningitis and septicemia, obtains transferrin-bound iron by expressing two outer membrane-located transferrin-binding proteins, TbpA and TbpB. A novel system was developed to investigate the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618fa55d2dc8c140fe9379550ba92e39
https://pubmed.ncbi.nlm.nih.gov/15664936
https://pubmed.ncbi.nlm.nih.gov/15664936