Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Christopher L D McMillan"'
Autor:
Cecy R Xi, Arianna Di Fazio, Naveed Ahmed Nadvi, Karishma Patel, Michelle Sui Wen Xiang, Hui Emma Zhang, Chandrika Deshpande, Jason K K Low, Xiaonan Trixie Wang, Yiqian Chen, Christopher L D McMillan, Ariel Isaacs, Brenna Osborne, Ana Júlia Vieira de Ribeiro, Geoffrey W McCaughan, Joel P Mackay, W Bret Church, Mark D Gorrell
Publikováno v:
Molecules, Vol 25, Iss 22, p 5392 (2020)
Proteases catalyse irreversible posttranslational modifications that often alter a biological function of the substrate. The protease dipeptidyl peptidase 4 (DPP4) is a pharmacological target in type 2 diabetes therapy primarily because it inactivate
Externí odkaz:
https://doaj.org/article/fa9dcf2606954561b940299e84274b4d
Publikováno v:
Expert Review of Vaccines, Vol 0, Iss 0 (2023)
Introduction Microneedles are emerging as a promising technology for vaccine delivery, with numerous advantages over traditional needle and syringe methods. Preclinical studies have demonstrated the effectiveness of MAPs in inducing robust immune res
Externí odkaz:
https://doaj.org/article/4ecb781fea1a40208370ae0a080e5da2
Autor:
Andrew Young, Ariel Isaacs, Connor A. P. Scott, Naphak Modhiran, Christopher L. D. McMillan, Stacey T. M. Cheung, Jennifer Barr, Glenn Marsh, Nazia Thakur, Dalan Bailey, Kenneth S. M. Li, Hayes K. H. Luk, Kin-Hang Kok, Susanna K. P. Lau, Patrick C. Y. Woo, Wakako Furuyama, Andrea Marzi, Paul R. Young, Keith J. Chappell, Daniel Watterson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The COVID-19 pandemic response has shown how vaccine platform technologies can be used to rapidly and effectively counteract a novel emerging infectious disease. The speed of development for mRNA and vector-based vaccines outpaced those of subunit va
Externí odkaz:
https://doaj.org/article/8e789c5618974f6bb15905f04f170ac6
Autor:
Mahali S. Morgan, Kexin Yan, Thuy T. Le, Ryan A. Johnston, Alberto A. Amarilla, David A. Muller, Christopher L. D. McMillan, Naphak Modhiran, Daniel Watterson, James R. Potter, Julian D.J. Sng, Mary Lor, Devina Paramitha, Ariel Isaacs, Alexander A. Khromykh, Roy A. Hall, Andreas Suhrbier, Daniel J. Rawle, Jody Hobson-Peters
Publikováno v:
Viruses, Vol 15, Iss 1, p 139 (2022)
The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned an ongoing demand for new research reagents and interventions. Herein we describe a panel of monoclonal ant
Externí odkaz:
https://doaj.org/article/82d6e8999d344525a4e59c50bacc8174
Autor:
Alberto A. Amarilla, Naphak Modhiran, Yin Xiang Setoh, Nias Y. G. Peng, Julian D. J. Sng, Benjamin Liang, Christopher L. D. McMillan, Morgan E. Freney, Stacey T. M. Cheung, Keith J. Chappell, Alexander A. Khromykh, Paul R. Young, Daniel Watterson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been identified as the causative agent of coronavirus disease 2019 and is capable of human-to-human transmission and rapid global spread. The rapid emergence and global spread of SARS-C
Externí odkaz:
https://doaj.org/article/b9bd3e7b12d24353a530ca72de242d89
Autor:
Christopher L. D. McMillan, Armira Azuar, Jovin J. Y. Choo, Naphak Modhiran, Alberto A. Amarilla, Ariel Isaacs, Kate E. Honeyman, Stacey T. M. Cheung, Benjamin Liang, Maria J. Wurm, Paco Pino, Joeri Kint, Germain J. P. Fernando, Michael J. Landsberg, Alexander A. Khromykh, Jody Hobson-Peters, Daniel Watterson, Paul R. Young, David A. Muller
Publikováno v:
Vaccines, Vol 10, Iss 4, p 578 (2022)
The ongoing coronavirus disease 2019 (COVID-19) pandemic continues to disrupt essential health services in 90 percent of countries today. The spike (S) protein found on the surface of the causative agent, the SARS-CoV-2 virus, has been the prime targ
Externí odkaz:
https://doaj.org/article/047b2bd3483b4cd9b6da0a66f2543ada
Autor:
Camille F. de Oliveira, Walter F. F. Neto, Carla P. da Silva, Ana Claudia S. Ribeiro, Lívia C. Martins, Alana W. de Sousa, Maria N. O. Freitas, Jannifer O. Chiang, Franko A. Silva, Eder B. dos Santos, Daniele B. A. Medeiros, Gleiciane S. Pinheiro, Gleiciane F. Brandão, Valéria L. Carvalho, Raimunda S. S. Azevedo, Pedro F. C. Vasconcelos, Igor B. Costa, Iran B. Costa, Mirleide C. dos Santos, Luana S. Soares, Rayssa L. S. Bedran, James L. Ferreira, Alberto A. Amarilla, Naphak Modhiran, Christopher L. D. McMillan, Morgan E. Freney, David A. Muller, Daniel Watterson, Lívia M. N. Casseb, Daniele F. Henriques
Publikováno v:
Vaccines, Vol 10, Iss 5, p 690 (2022)
The COVID-19 pandemic is the biggest public health threat facing the world today. Multiple vaccines have been approved; however, the emergence of viral variants such as the recent Omicron raises the possibility of booster doses to achieve adequate pr
Externí odkaz:
https://doaj.org/article/f36dceca88a541f389a561d2864afa40
Autor:
Jovin J. Y. Choo, Christopher L. D. McMillan, Germain J. P. Fernando, Roy A. Hall, Paul R. Young, Jody Hobson-Peters, David A. Muller
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1301 (2021)
Alternative delivery systems such as the high-density microarray patch (HD-MAP) are being widely explored due to the variety of benefits they offer over traditional vaccine delivery methods. As vaccines are dry coated onto the HD-MAP, there is a need
Externí odkaz:
https://doaj.org/article/c3781db295914ec3b1fdb0bb6b7d13c9
Autor:
Ariel Isaacs, Zheyi Li, Stacey T. M. Cheung, Danushka K. Wijesundara, Christopher L. D. McMillan, Naphak Modhiran, Paul R. Young, Charani Ranasinghe, Daniel Watterson, Keith J. Chappell
Publikováno v:
Vaccines, Vol 9, Iss 2, p 71 (2021)
Subunit vaccines exhibit favorable safety and immunogenicity profiles and can be designed to mimic native antigen structures. However, pairing with an appropriate adjuvant is imperative in order to elicit effective humoral and cellular immune respons
Externí odkaz:
https://doaj.org/article/3494df92d5ce414d98639c9f8230e28f
Autor:
Ariel Isaacs, Alberto A. Amarilla, Julio Aguado, Naphak Modhiran, Eduardo A. Albornoz, Alireza A. Baradar, Christopher L. D. McMillan, Jovin J. Y. Choo, Adi Idris, Aroon Supramaniam, Nigel A. J. McMillan, David A. Muller, Paul R. Young, Trent M. Woodruff, Ernst J. Wolvetang, Keith J. Chappell, Daniel Watterson
Publikováno v:
Frontiers in Immunology. 13
Since the start of the COVID-19 pandemic, multiple waves of SARS-CoV-2 variants have emerged. Of particular concern is the omicron variant, which harbors 28 mutations in the spike glycoprotein receptor binding and N-terminal domains relative to the a