Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Christopher L Brett"'
Autor:
Daniel Lockshon, Carissa Perez Olsen, Christopher L Brett, Andrei Chertov, Alexey J Merz, Daniel A Lorenz, Marc R Van Gilst, Brian K Kennedy
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45049 (2012)
Preservation of both the integrity and fluidity of biological membranes is a critical cellular homeostatic function. Signaling pathways that govern lipid bilayer fluidity have long been known in bacteria, yet no such pathways have been identified in
Externí odkaz:
https://doaj.org/article/6d006fe966ef4ab49fc12a2321c444c0
Autor:
Christopher L Brett, Laura Kallay, Zhaolin Hua, Richard Green, Anthony Chyou, Yongqiang Zhang, Todd R Graham, Mark Donowitz, Rajini Rao
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17619 (2011)
Protons, the smallest and most ubiquitous of ions, are central to physiological processes. Transmembrane proton gradients drive ATP synthesis, metabolite transport, receptor recycling and vesicle trafficking, while compartmental pH controls enzyme fu
Externí odkaz:
https://doaj.org/article/4c4a7e183a0740b890c3fc5bd8256877
Publikováno v:
Journal of Radiation Oncology. 9:185-189
For patients presenting with recurrent, inoperable, or metastatic sarcoma, treatment options are limited. The inherent low radiosensitivity of many sarcoma histologies can limit effectiveness of palliative radiation for these patients. Stereotactic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2c635366aa08a2141e35a7abb432a94
https://doi.org/10.1007/s13566-020-00438-8
https://doi.org/10.1007/s13566-020-00438-8
A single-institution study of intraoperative radiation therapy (IORT) using electronic brachytherapy
Autor:
Raeshell S. Sweeting, Benjin D. Facer, Ana M. Grau, Christopher L. Brett, Ingrid M. Meszoely, A. Bapsi Chakravarthy, Manuel Morales-Paliza
Publikováno v:
Journal of Radiation Oncology. 9:59-65
Two prospective randomized trials, TARGIT-A and ELIOT, have shown intraoperative radiation (IORT) to be safe and well-tolerated in low-risk patients. Electronic IORT with the Xoft Axxent system has few long-term reported results. A total of 100 patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d345a688971f69dc123cdd843a876775
https://doi.org/10.1007/s13566-020-00418-y
https://doi.org/10.1007/s13566-020-00418-y
Autor:
Rutilio A. Fratti, Logan R. Hurst, Christopher L. Brett, Chi Zhang, David A. Rivera-Kohr, Tom Kazmirchuk
The role of sphingolipids in controlling the endolysosomal membrane trafficking remains unclear. Here, we show that inSaccharomyces cerevisiaesphingolipids containing very long-chain fatty-acids (VLCAs) promote homotypic vacuolar fusion. Yeast that l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77426a4acc93078dd1f9275f2dc4026b
https://doi.org/10.1101/2020.02.17.953331
https://doi.org/10.1101/2020.02.17.953331
Autor:
Christopher L. Brett, William G. Stevenson, Asad A. Aboud, Rashed Karim, Eric T. Shinohara, Jason Cook
Publikováno v:
Practical radiation oncology. 11(1)
Purpose A recent clinical trial has demonstrated that noninvasive radioablation (NIRA) has the potential to reduce recurrent ventricular tachycardia (VT) that is refractory to drugs and standard catheter ablation. Electroanatomic mapping (EAM) that w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4494e019451bd0fa86d18301ea02944c
https://pubmed.ncbi.nlm.nih.gov/32416269
https://pubmed.ncbi.nlm.nih.gov/32416269
Autor:
Andrew M. Harrison, Cammi Bowman, Andree Koop, Gaja F. Shaughnessy, Jordan Ray, M. Caroline Burton, Lauren F. Cornell, Christopher L. Brett, Scott A Helgeson
Publikováno v:
Southern Medical Journal. 111:87-92
Objectives The use of continuous pulse oximetry (CPOX) is ubiquitous among hospitalized patients, despite limited evidence that it improves clinical outcomes. The objective of this study was to reduce the use of CPOX among hospitalized patients in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379fa5f30de293f14b54a7c89c1caf36
https://doi.org/10.14423/smj.0000000000000766
https://doi.org/10.14423/smj.0000000000000766
Publikováno v:
Molecular Biology of the Cell
Endosomal Na+(K+)/H+ exchangers (NHEs) are important for endocytosis but it is unclear how they contribute. A cell-free assay was used to show that the yeast NHE Nhx1 regulates multivesicular body–lysosome fusion, the last step of endocytosis, demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece090424d450c479f8a208235bcedea
http://europepmc.org/articles/PMC5996954
http://europepmc.org/articles/PMC5996954
Publikováno v:
Traffic. 19:138-149
When marked for degradation, surface receptor and transporter proteins are internalized and delivered to endosomes where they are packaged into intralumenal vesicles (ILVs). Many rounds of ILV formation create multivesicular bodies (MVBs) that fuse w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b11adfb58ba9dbf5b4ef9f69b021205
https://doi.org/10.1111/tra.12543
https://doi.org/10.1111/tra.12543
Publikováno v:
Molecular Biology of the Cell
When vacuolar lysosomes fuse, an intralumenal membrane fragment is produced and degraded by hydrolyses. How or why this fragment forms is not entirely understood. We show that the fusion machinery regulates stalk expansion during lipid bilayer fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696e0c078e4a22714d0315b816a43df7
http://europepmc.org/articles/PMC5231899
http://europepmc.org/articles/PMC5231899