Zobrazeno 1 - 10
of 846
pro vyhledávání: '"Christopher L, Wolfgang"'
Autor:
Ankit Chhoda, Anup Sharma, Bethsebie Sailo, Haoyu Tang, Nensi Ruzgar, Wan Ying Tan, Lee Ying, Rishabh Khatri, Anand Narayanan, Shrikant Mane, Bony De Kumar, Laura D. Wood, Christine Iacobuzio-Donahue, Christopher L. Wolfgang, John W. Kunstman, Ronald R. Salem, James J. Farrell, Nita Ahuja
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-8 (2023)
Abstract Background Intraductal papillary mucinous neoplasms (IPMNs), a type of cystic pancreatic cancer (PC) precursors, are increasingly identified on cross-sectional imaging and present a significant diagnostic challenge. While surgical resection
Externí odkaz:
https://doaj.org/article/546ba8af962b49deaa4afd35f88e5578
Publikováno v:
Cancers, Vol 16, Iss 3, p 489 (2024)
Pancreatic ductal adenocarcinoma (PDAC) remains associated with poor outcomes with a 5-year survival of 12% across all stages of the disease. These poor outcomes are driven by a delay in diagnosis and an early propensity for systemic dissemination of
Externí odkaz:
https://doaj.org/article/b4ae280b68be46ffa1b9ac7bcd297510
Autor:
Logan R. McNeil, BA, Alex B. Blair, MD, Robert W. Krell, MD, Chunmeng Zhang, MD, Aslam Ejaz, MD, MPH, Vincent P. Groot, MD, PhD, Georgios Gemenetzis, MD, James C. Padussis, MD, Massimo Falconi, MD, Christopher L. Wolfgang, MD, PhD, Matthew J. Weiss, MD, Chandrakanth Are, MD, MBA, Jin He, MD, PhD, Bradley N. Reames, MD, MS
Publikováno v:
Surgery Open Science, Vol 10, Iss , Pp 97-105 (2022)
Background: Recent literature suggests wide variations exist in the international management of locally advanced pancreatic cancer. This study sought to evaluate how geography contributes to variations in management of locally advanced pancreatic can
Externí odkaz:
https://doaj.org/article/411b220dbef84f7aaf33c5c02f42df44
Autor:
Georgios Antonios Margonis, Nikolaos Andreatos, Jane Wang, Matthew J. Weiss, Christopher L. Wolfgang
Publikováno v:
Journal of Pancreatology, Vol 5, Iss 1, Pp 36-40 (2022)
Abstract. Although the natural history of recurrence/progression in patients with intraductal papillary mucinous neoplasms (IPMN) of the pancreas has not been studied thoroughly, the three principal mechanisms have been identified: (a) presence of re
Externí odkaz:
https://doaj.org/article/7cd3b31b09404d0b9f02ffac0fcf5c57
Autor:
Tao Xia, Keyu Li, Nan Niu, Yingkuan Shao, Ding Ding, Dwayne L. Thomas, Hao Jing, Kenji Fujiwara, Haijie Hu, Arsen Osipov, Chunhui Yuan, Christopher L. Wolfgang, Elizabeth D. Thompson, Robert A. Anders, Jin He, Yiping Mou, Adrian G. Murphy, Lei Zheng
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-20 (2022)
Abstract Background Immunotherapy has demonstrated a limited clinical efficacy in approximately 5% of cholangiocarcinoma. The main challenges for an effective immunotherapy response in cholangiocarcinoma arise from the tumor microenvironment, which i
Externí odkaz:
https://doaj.org/article/0811bea100fd47df96bb43572ac97480
Autor:
Kacey Chae, MD, Jordan Perlman, MD, Ryan B. Fransman, MD, Christopher L. Wolfgang, MD, PhD, Ana De Jesus-Acosta, MD, Nestoras Mathioudakis, MD
Publikováno v:
AACE Clinical Case Reports, Vol 7, Iss 6, Pp 379-382 (2021)
Objective: We describe a rare case of profound subcutaneous insulin resistance (SIR) presumed due to a paraneoplastic process caused by pancreatic adenocarcinoma that improved with intravenous insulin and tumor resection. Methods: An 80-year-old man
Externí odkaz:
https://doaj.org/article/6f8d0a8eb44945a6a5ece0113c149824
Autor:
Arsen Osipov, Alex B. Blair, Juliane Liberto, Jianxin Wang, Keyu Li, Brian Herbst, Yao Xu, Shiqi Li, Nan Niu, Rufiaat Rashid, Ding Ding, Yanan Liu, Zaiqi Wang, Christopher L. Wolfgang, Richard A. Burkhart, Daniel Laheru, Lei Zheng
Publikováno v:
Cancer Biology & Medicine, Vol 18, Iss 1, Pp 206-214 (2021)
Objective: Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy, due in large part to its resistance to conventional therapies, including radiotherapy (RT). Despite RT exerting a modest antitumor response, it has also been shown to promote
Externí odkaz:
https://doaj.org/article/39e6bd391a9843878fe8179f827b11f3
Autor:
Katsunori Imai, MD, PhD, FACS, Georgios A. Margonis, MD, PhD, Jaeyun Wang, MD, Christopher L. Wolfgang, MD, PhD, Hideo Baba, MD, PhD, FACS, Matthew J. Weiss, MD, FACS
Publikováno v:
Journal of Pancreatology, Vol 3, Iss 2, Pp 81-85 (2020)
Abstract. Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive malignancies, and the majority of patients with PDAC present with metastatic disease, mainly in the liver, at the time of diagnosis. Surgical resection is the onl
Externí odkaz:
https://doaj.org/article/c8154d8c6d5f4bb39176ea8fd678fe64
Publikováno v:
Surgery Open Science, Vol 1, Iss 2, Pp 49-55 (2019)
Pancreatic cancer is a lethal disease in a large part due to the systemic nature at the time of diagnosis. In those patients who undergo a potentially curative resection of pancreatic cancer, the overwhelming majority will have systemic relapse. Circ
Externí odkaz:
https://doaj.org/article/f69e2c30d7e4475eb19fcd6290289345
Autor:
Ling Li, Gilad Halpert, Michael G. Lerner, Haijie Hu, Peter Dimitrion, Matthew J. Weiss, Jin He, Benjamin Philosophe, Richard Burkhart, William R. Burns, Russell N. Wesson, Andrew MacGregor Cameron, Christopher L. Wolfgang, Christos Georgiades, Satomi Kawamoto, Nilofer S. Azad, Mark Yarchoan, Stephen J. Meltzer, Kiyoko Oshima, Laura M. Ensign, Joel S. Bader, Florin M. Selaru
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Hepatocellular carcinoma (HCC) is the sixth most common and the fourth most deadly cancer worldwide. The development cost of new therapeutics is a major limitation in patient outcomes. Importantly, there is a paucity of preclinical HCC models in whic
Externí odkaz:
https://doaj.org/article/f683fedaae0d4fbb8bdd07f74ee54fb0