Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christopher Kirkham"'
Autor:
Susanne Paukner, Sandra Kimber, Charlotte Cumper, Tina Rea-Davies, Lorena Sueiro Ballesteros, Christopher Kirkham, Adam Hargreaves, Steven P. Gelone, Claire Richards, Wolfgang W. Wicha
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5401 (2024)
Lefamulin is a first-in-class systemic pleuromutilin antimicrobial and potent inhibitor of bacterial translation, and the most recent novel antimicrobial approved for the treatment of community-acquired pneumonia (CAP). It exhibits potent antibacteri
Externí odkaz:
https://doaj.org/article/465c8dafc02148c7bdc3396a19a8661a
Autor:
Russell Garland, Christopher Kirkham, Michelle Yap, Louise Brackenbury, Tommaso Iannitti, Robert Nunan, S Jenkinson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/531c9872398740619950be86a2829914
Autor:
Wolfgang W Wicha, Sandy Kimber, Charlotte Cumper, Hon S Lam, Lorena S Ballesteros, Christopher Kirkham, Claire Richards, Steven P Gelone, Susanne Paukner
Publikováno v:
Open Forum Infectious Diseases. 9
Background Lefamulin (LEF) is a pleuromutilin antibiotic approved by the United States (US) FDA for the treatment of community-acquired bacterial pneumonia in adults. In addition to the potent antibacterial activity, LEF has demonstrated anti-inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc199bba27f724b533b73268cc32c25
https://doi.org/10.1093/ofid/ofac492.1808
https://doi.org/10.1093/ofid/ofac492.1808
Autor:
Lauren Kelsey, Karin Latta, Joey Kolb, Bincy John, Ilona Aylott, Daniel Rocca, Alexandru Bacita, Christopher Kirkham, Patrick Walters, Charlotte Humphery, Lorena Sueiro Ballesteros, Jezrom Self-Fordham, Louise Brackenbury, Chassidy Hall, Harris David, Julia Schueler, Robert Nunan
Publikováno v:
Cancer Research. 83:4097-4097
Chimeric Antigen Receptor (CAR)-T cell therapy has achieved great success in treating a variety of liquid tumors, in particular CD19+ lymphomas. CAR technology is advancing rapidly, with notable improvements in efficacy, safety and complexity as huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51a89f5fb6184aade91288ca0c18f921
https://doi.org/10.1158/1538-7445.am2023-4097
https://doi.org/10.1158/1538-7445.am2023-4097
Autor:
Tommaso Iannitti, Michelle Yap, Christopher Kirkham, Russell Garland, Louise Brackenbury, S Jenkinson, Robert Nunan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Lack of efficacy is a common cause of failure in Phase I and Phase II clinical trials. Pharmacodynamic (PD) biomarker assays can demonstrate target engagement and proof of mechanism; both key components to improve trial success. Biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea03b1312e0145eaf0a194368778b9b
https://doi.org/10.1136/jitc-2020-sitc2020.0006
https://doi.org/10.1136/jitc-2020-sitc2020.0006
Autor:
Christopher Kirkham
Information on the seismic data, calibration and dating of the stratigraphy, as well as additional seismic and well figures that highlight the tie of well La52 to the seismic welds between the base of the mud canopy and pre-salt, interdigitating lens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396161727582d3bff99667ee90532e15
https://doi.org/10.1130/geol.26213s.12221921
https://doi.org/10.1130/geol.26213s.12221921
Autor:
Koichi Murata, Shuhei Yagi, Takashi Kanazawa, Satoshi Tsubomatsu, Christopher Kirkham, Koh-ichi Nittoh, David R Bowler, Kazushi Miki
Publikováno v:
Nano Futures. 5:045005
Conventional doping processes are no longer viable for realizing extreme structures, such as a δ-doped layer with multiple elements, such as the heavy Bi, within the silicon crystal. Here, we demonstrate the formation of (Bi + Er)-δ-doped layer bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae090d5062d78ea3efd44ac1250dc15
https://doi.org/10.1088/2399-1984/ac421d
https://doi.org/10.1088/2399-1984/ac421d
Autor:
Christopher Kirkham, Tomoya Ono
Publikováno v:
Materials Science Forum. 858:457-460
We investigated the effect of SiC stacking on the 4H-SiC/SiO2 interface via first principles calculations. Interlayer states are observed along the SiC conduction band edge, and are affected by the local structure at the interface. The location of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec2d6f85b37cba15b3af294685664f5
https://doi.org/10.4028/www.scientific.net/msf.858.457
https://doi.org/10.4028/www.scientific.net/msf.858.457
Autor:
Renan Villarreal, Alessandro Scarfato, David R. Bowler, Christoph Renner, Christopher Kirkham
Publikováno v:
Journal of Applied Physics, Vol. 125, No 18 (2019) P. 184301
The surface diffusion potential landscape plays an essential role in a number of physical and chemical processes such as self-assembly and catalysis. Diffusion energy barriers can be calculated theoretically for simple systems, but there is currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20c8405cc30e70ee360a1d64acdc288
Autor:
Ch. Renner, S. A. Köster, Maria Longobardi, Christopher Kirkham, Renan Villarreal, David R. Bowler
Publikováno v:
Physical Review. B, Condensed Matter, Vol. 96, No 23 (2017) P. 235421
Atomic nanolines are one dimensional systems realized by assembling many atoms on a substrate into long arrays. The electronic properties of the nanolines depend on those of the substrate. Here, we demonstrate that to fully understand the electronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81079190f43ca717f8fcbb3559c9812
https://doi.org/10.1103/physrevb.96.235421
https://doi.org/10.1103/physrevb.96.235421