Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Christopher K. W. Chan"'
Publikováno v:
The Journal of Organic Chemistry
Synthesis of partially 2'/3'-O-acetylated oligoribonucleotides has been accomplished by using a 2'/3'-O-acetyl orthogonal protecting group strategy in which non-nucleophilic strong-base (DBU) labile nucleobase protecting groups and a UV-light cleavab
Autor:
John D. Sutherland, Saidul Islam, Christopher K. W. Chan, Jianfeng Xu, Colm D. Duffy, Béatrice Gerland, Matthew W. Powner, Frank R. Bowler
Publikováno v:
Nature Chemistry. 5:383-389
The recent synthesis of pyrimidine ribonucleoside-2',3'-cyclic phosphates under prebiotically plausible conditions has strengthened the case for the involvement of ribonucleic acid (RNA) at an early stage in the origin of life. However, a prebiotic c