Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Christopher K. Garcia"'
Autor:
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel-Hakeem, Kito Nzingha, Zhen Zhang, Hua Huang, Makoto Kurachi, Yuki Muroyama, Yinghui Jane Huang, Leon L Su, Lora Picton, Helene Decaluwe, Alexander C Huang, Shelley L Berger, Christopher K Garcia, E. John Wherry
Publikováno v:
The Journal of Immunology. 206:14.13-14.13
Exhaustion gradually establishes in chronically stimulated CD8s and this process is not reverted by current therapeutic approaches due to establishment of a stable epigenetic program. Recent advances have informed on the developmental process of exha
Autor:
Eleonora Trotta, Paul H. Bessette, Stephanie L. Silveria, Lauren K. Ely, Kevin Jude, Charles R. Holst, Anthony Coyle, Christopher K. Garcia, Natasha K. Crellin, Isaac J. Rondon, Jeffrey A. Bluestone
Publikováno v:
The Journal of Immunology. 200:176.4-176.4
Interleukin-2 (IL-2) has been shown to suppress immune pathologies by preferentially expanding regulatory T cells (Treg). However, this therapy has been limited by off-target complications due to pathogenic cell expansion. Recent efforts have been fo