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pro vyhledávání: '"Christopher K. Crowell"'
Autor:
Rene Kupfer, Cheryll Williams-Skipp, Yunxia Tao, Steven Sain, Robert I. Scheinman, Benjamin J. Stewart, Dhavalkumar D. Patel, Christopher K. Crowell
Publikováno v:
Molecular Immunology. 43:335-345
Thymic selection requires that diverse self antigens be presented to developing thymocytes by stromal cells. Consistent with this function, medullary thymic epithelial cells have been shown to express a large number of genes, many of which are tissue
Autor:
Qiang Qin, Christopher K. Crowell, Gustavo Grampp, Richard A. Radcliffe, Robert I. Scheinman, Gary Rogers
Publikováno v:
Biotechnology and bioengineering. 99(1)
Recombinant human erythropoietin (rHuEPO) produced in a human kidney fibrosarcoma cell line, HT1080, was used as a model to study the effects of sodium butyrate (SB) on protein glycosylation. Treatment with 2 mM SB resulted in complex changes with re
Publikováno v:
Biotechnology and bioengineering. 96(3)
The manufacture of secreted proteins is complicated by the need for both high levels of expression and appropriate processing of the nascent polypeptide. For glycoproteins, such as erythropoietin (EPO), posttranslational processing involves the addit